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The protein encoded by CNOT6 is a subunit of the CCR4-NOT core transcriptional regulation complex. Additionally we are shipping CNOT6 Antibodies (34) and CNOT6 Proteins (4) and many more products for this protein.
The CNOT6 rs2453176 Single Nucleotide Polymorphism may be a new functional susceptible locus for lung cancer risk.
miR (show MLXIP ELISA Kits)-29c-3p promotes the senescence of Mesenchymal stem cells by targeting CNOT6 through p53 (show TP53 ELISA Kits)-p21 (show CDKN1A ELISA Kits) and p16-pRB (show RB1 ELISA Kits) pathways.
These results indicate that Caf1 (show CHAF1B ELISA Kits) and Ccr4 (show CCR4 ELISA Kits) cooperate in mRNA deadenylation and suggest that the enzyme activities of Caf1 (show CHAF1B ELISA Kits) and Ccr4 (show CCR4 ELISA Kits) are regulated via allosteric interactions within the nuclease (show DCLRE1C ELISA Kits) module.
Results identified CNOT6/CNOT6L (show CNOT6L ELISA Kits) as a key regulator of insulin-like growth factor-binding protein 5 (show IGFBP5 ELISA Kits), which mediates cell cycle arrest and senescence via a p53 (show TP53 ELISA Kits)-dependent pathway.
CCR4 (show CCR4 ELISA Kits) and BTG2 (show BTG2 ELISA Kits) interact and have a role in cell-cycle regulation
CCR4 (show CCR4 ELISA Kits) plays a role in the regulation of certain endogenous RARalpha (show RARA ELISA Kits) target genes and RCD1 (show RQCD1 ELISA Kits) and CCR4 (show CCR4 ELISA Kits) might mediate their function through their interaction with NIF-1 (show ZNF335 ELISA Kits)
hCCR4/cNOT6 targets DNA-damage response proteins
Data show that Ccr4 (show CCR4 ELISA Kits)-Not function in RNA splicing and nuclear export, and that CNOT6 binds CNOT8 (show CNOT8 ELISA Kits) in yeast two-hybrid assays.
The protein encoded by this gene is a subunit of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substates.
CCR4-NOT transcription complex subunit 6
, CCR4-NOT transcription complex, subunit 6
, Cytoplasmic deadenylase
, carbon catabolite repression 4 protein
, carbon catabolite repressor protein 4 homolog
, cytoplasmic deadenylase