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CCR4-NOT Transcription Complex, Subunit 7 Proteins (CNOT7)

The protein encoded by CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Additionally we are shipping CNOT7 Antibodies (37) and CNOT7 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNOT7 29883 Q9UIV1
CNOT7 18983 Q60809
Rat CNOT7 CNOT7 306492  
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Top CNOT7 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,750.00
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,750.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,750.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,750.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CNOT7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced CNOT7 Proteins

  1. Mouse (Murine) CNOT7 Protein expressed in Escherichia coli (E. coli) - ABIN667528 : Draper, Salvadore, Denis: Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex. in Molecular and cellular biology 1995 (PubMed)
    Show all 2 references for ABIN667528

More Proteins for CCR4-NOT Transcription Complex, Subunit 7 (CNOT7) Interaction Partners

Human CCR4-NOT Transcription Complex, Subunit 7 (CNOT7) interaction partners

  1. MEX3C (show MEX3C Proteins) associates with the cytoplasmic deadenylation complexes and ubiquitinates CNOT7.

  2. CNOT7/hCAF1 (show CNOT8 Proteins) is involved in ICAM-1 (show ICAM1 Proteins) and IL-8 (show IL8 Proteins) regulation by TTP (show ADAMTS13 Proteins) in HPMEC.

  3. CNOT7 is an antimicrobial protein and a regulator of the innate immune response.

  4. The anti-proliferative activity of BTG/TOB (show TDO2 Proteins) proteins is mediated via the Caf1a (show CHAF1B Proteins) (CNOT7) and Caf1b (show CHAF1A Proteins) (CNOT8 (show CNOT8 Proteins)) deadenylase subunits of the Ccr4 (show CCR4 Proteins)-not complex.

  5. CNOT7 is not the target tumor suppressor gene in the 8p22-23.1 colorectal cancer suppressor (show DCC Proteins) region.

  6. CAF1 (show CHAF1B Proteins) is a new regulator of PRMT1 (show PRMT1 Proteins)-dependent arginine methylation.

  7. antiproliferative region of human Tob (show TDO2 Proteins) (residues 1-138) and intact hCaf1 (show CNOT8 Proteins) were co-expressed in Escherichia coli, purified and successfully cocrystallized

  8. Data show that Ccr4 (show CCR4 Proteins)-Not function in RNA splicing and nuclear export, and that CNOT7 binds strongly with CNOT6 (show CNOT6 Proteins).

  9. Data show that efficient cell proliferation requires both CNOT7 and CNOT8 (show CNOT8 Proteins), although combined knockdown of both subunits further reduces cell proliferation indicating partial redundancy between these proteins.

Mouse (Murine) CCR4-NOT Transcription Complex, Subunit 7 (CNOT7) interaction partners

  1. Cnot7, a key component of deadenylation machinery, are also dormant maternal mRNAs that are recruited during oocyte maturation

  2. Collectively, our data support a model of CNOT7, TOB1, CNOT1, and RNA-binding proteins collectively exerting post-transcriptional control on a metastasis suppressive transcriptional program to drive tumor cell metastasis

  3. MK2 (show KCNA2 Proteins) phosphorylation reduces the ability of TTP (show ZFP36 Proteins) to promote deadenylation by inhibiting the recruitment of CAF1 deadenylase in a mechanism that does not involve sequestration of TTP (show ZFP36 Proteins) by 14-3-3 (show YWHAQ Proteins).

  4. mCAF1-deficient mouse phenotype could be linked to a defect(s) in germ cells and/or to inadequate Sertoli cell function, leading to seminiferous tubule disorganization and finally to a total disappearance of germ cells

  5. Gene deletion of Cnot7 caused abnormal sperm morphology in Sertoli cells from knockout mice.

  6. Cnot7 is expressed in osteoblasts and is associated with mineralization.

  7. Cnot7 is an endogenous suppressor of bone mass in adult mice and inhibits bone mass phenotype actions

  8. Show that a let-7 miRNA-loaded RNA-induced silencing complex interacts with the poly(A)-binding protein and the CAF1 and CCR4 (show CCR4 Proteins) deadenylases for miRNA mediated deadenylation.

CNOT7 Protein Profile

Protein Summary

The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Gene names and symbols associated with CNOT7

  • CCR4-NOT transcription complex, subunit 7 (CNOT7)
  • ccr4-not transcription complex, subunit 7 (CNL04550)
  • CCR4-NOT transcription complex, subunit 7 (GL50803_10606)
  • CCR4-NOT transcription complex, subunit 7 (GL50803_8209)
  • ccr4-not transcription complex, subunit 7 (CGB_D2510C)
  • CCR4-NOT transcription complex, subunit 7 (cnot7)
  • CCR4-NOT transcription complex, subunit 7 (Cnot7)
  • AU022737 protein
  • CAF-1 protein
  • Caf1 protein
  • Caf1a protein
  • CNOT7 protein
  • fd59c07 protein
  • fj07d05 protein
  • hCAF-1 protein
  • Pop2 protein
  • wu:fd59c07 protein
  • wu:fj07d05 protein
  • zgc:153168 protein

Protein level used designations for CNOT7

CCR4-NOT transcription complex, subunit 7 , CCR4-NOT transcription complex subunit 7 , ccr4-not transcription complex, subunit 7 , CAF-1 , CCR4-associated factor 1 , BTG1 binding factor 1 , BTG1-binding factor 1 , carbon catabolite repressor protein (CCR4)-associative factor 1 , POP2 homolog , catabolite repressor protein (CCR4)-associative factor 1

GENE ID SPECIES
464006 Pan troglodytes
702192 Macaca mulatta
3254820 Cryptococcus neoformans var. neoformans JEC21
5698745 Giardia lamblia ATCC 50803
100154442 Sus scrofa
5697031 Giardia lamblia ATCC 50803
10191122 Cryptococcus gattii WM276
768119 Danio rerio
734751 Xenopus laevis
422733 Gallus gallus
29883 Homo sapiens
482895 Canis lupus familiaris
508055 Bos taurus
18983 Mus musculus
306492 Rattus norvegicus
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