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CCR4-NOT Transcription Complex, Subunit 8 Proteins (CNOT8)

Ubiquitous transcription factor required for a diverse set of processes. Additionally we are shipping CNOT8 Antibodies (88) and CNOT8 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CNOT8 CNOT8 363603  
CNOT8 9337 Q9UFF9
CNOT8 69125 Q9D8X5
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Top CNOT8 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$498.21
Details

CNOT8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for CCR4-NOT Transcription Complex, Subunit 8 (CNOT8) Interaction Partners

Zebrafish CCR4-NOT Transcription Complex, Subunit 8 (CNOT8) interaction partners

  1. Pharmacological inhibition of FGF signaling or a mutation in the fgf3 (show FGF3 Proteins) gene can compensate the gain of caudal hypothalamic dopaminergic neurons in cnot8m1061 mutants, indicating a role for Fgf3 (show FGF3 Proteins) in control of development of this dopaminergic population

Human CCR4-NOT Transcription Complex, Subunit 8 (CNOT8) interaction partners

  1. These results indicate that Caf1 (show CHAF1B Proteins) and Ccr4 (show CCR4 Proteins) cooperate in mRNA deadenylation and suggest that the enzyme activities of Caf1 (show CHAF1B Proteins) and Ccr4 (show CCR4 Proteins) are regulated via allosteric interactions within the nuclease (show DCLRE1C Proteins) module.

  2. CNOT7 (show CNOT7 Proteins)/hCAF1 is involved in ICAM-1 (show ICAM1 Proteins) and IL-8 (show IL8 Proteins) regulation by TTP (show ADAMTS13 Proteins) in HPMEC.

  3. show that SMG7 binds directly to POP2, a catalytic subunit of the CCR4 (show CCR4 Proteins)-NOT deadenylase complex, and elicits deadenylation-dependent decapping and 5'-to-3' decay of NMD targets

  4. The anti-proliferative activity of BTG/TOB (show TDO2 Proteins) proteins is mediated via the Caf1a (show CHAF1B Proteins) (CNOT7 (show CNOT7 Proteins)) and Caf1b (show CHAF1A Proteins) (CNOT8) deadenylase subunits of the Ccr4 (show CCR4 Proteins)-not complex.

  5. The NOT1 MIF4G domain binds CAF1 through a pre-formed interface and leaves the CAF1 catalytic site fully accessible to RNA substrates.

  6. N-terminus played a role in modulating hCaf1 activity, stability and aggregation

  7. Together, these results indicate that Tob (show TDO2 Proteins) mediates the recruitment of Caf1 (show CHAF1B Proteins) to the target of CPEB3 (show CPEB3 Proteins) and elicits deadenylation and decay of the mRNA.

  8. MK2 (show KCNA2 Proteins) phosphorylation reduces the ability of TTP (show ADAMTS13 Proteins) to promote deadenylation by inhibiting the recruitment of CAF1 (show CHAF1B Proteins) deadenylase in a mechanism that does not involve sequestration of TTP (show ADAMTS13 Proteins) by 14-3-3 (show YWHAQ Proteins).

  9. Tob (show TDO2 Proteins) interactions with Caf1 (show CHAF1B Proteins) and a C-terminal domain of PABPC1 (show PABPC1 Proteins)

  10. CCR4 (show CCR4 Proteins)-NOT is the deadenylase that removes poly(A) from messages destabilized by miRNAs in human cells.

CNOT8 Protein Profile

Protein Summary

Ubiquitous transcription factor required for a diverse set of processes. The CCR4-NOT complex functions as general transcription regulation complex (By similarity).

Gene names and symbols associated with CNOT8

  • CCR4-NOT transcription complex, subunit 8 (Cnot8)
  • CCR4-NOT transcription complex, subunit 8 (CNOT8)
  • CCR4-NOT transcription complex, subunit 8 (cnot8)
  • CCR4-NOT transcription complex subunit 8 (PAAG_04884)
  • CCR4-NOT transcription complex subunit 8 (VDBG_08730)
  • 1500015I04Rik protein
  • 1810022F04Rik protein
  • AA536816 protein
  • AU015770 protein
  • AU043059 protein
  • CAF1 protein
  • Caf1b protein
  • CALIF protein
  • hCAF1 protein
  • POP2 protein
  • wu:fe49a05 protein
  • zgc:63844 protein

Protein level used designations for CNOT8

CCR4-NOT transcription complex subunit 8 , CCR4-NOT transcription complex, subunit 8 , ccr4-not transcription complex subunit 8 , CAF1-like protein , CAF2 , CALIFp , CCR4-associated factor 8 , PGK promoter directed over production

GENE ID SPECIES
363603 Rattus norvegicus
416255 Gallus gallus
379811 Xenopus laevis
406788 Danio rerio
549332 Xenopus (Silurana) tropicalis
100528541 Ictalurus punctatus
533443 Bos taurus
9096558 Paracoccidioides sp. 'lutzii' Pb01
9534322 Verticillium alfalfae VaMs.102
9337 Homo sapiens
69125 Mus musculus
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