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The protein encoded by CNOT6 is a subunit of the CCR4-NOT core transcriptional regulation complex. Additionally we are shipping CNOT6 Proteins (4) and many more products for this protein.
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The CNOT6 rs2453176 Single Nucleotide Polymorphism may be a new functional susceptible locus for lung cancer risk.
miR (show MLXIP Antibodies)-29c-3p promotes the senescence of Mesenchymal stem cells by targeting CNOT6 through p53 (show TP53 Antibodies)-p21 (show CDKN1A Antibodies) and p16 (show CDKN2A Antibodies)-pRB (show RB1 Antibodies) pathways.
These results indicate that Caf1 (show CHAF1B Antibodies) and Ccr4 (show CCR4 Antibodies) cooperate in mRNA deadenylation and suggest that the enzyme activities of Caf1 (show CHAF1B Antibodies) and Ccr4 (show CCR4 Antibodies) are regulated via allosteric interactions within the nuclease (show DCLRE1C Antibodies) module.
Results identified CNOT6/CNOT6L (show CNOT6L Antibodies) as a key regulator of insulin-like growth factor-binding protein 5 (show IGFBP5 Antibodies), which mediates cell cycle arrest and senescence via a p53 (show TP53 Antibodies)-dependent pathway.
CCR4 (show CCR4 Antibodies) and BTG2 (show BTG2 Antibodies) interact and have a role in cell-cycle regulation
CCR4 (show CCR4 Antibodies) plays a role in the regulation of certain endogenous RARalpha (show RARA Antibodies) target genes and RCD1 (show RQCD1 Antibodies) and CCR4 (show CCR4 Antibodies) might mediate their function through their interaction with NIF-1 (show ZNF335 Antibodies)
hCCR4/cNOT6 targets DNA-damage response proteins
Data show that Ccr4 (show CCR4 Antibodies)-Not function in RNA splicing and nuclear export, and that CNOT6 binds CNOT8 (show CNOT8 Antibodies) in yeast two-hybrid assays.
The protein encoded by this gene is a subunit of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substates.
CCR4-NOT transcription complex subunit 6
, CCR4-NOT transcription complex, subunit 6
, Cytoplasmic deadenylase
, carbon catabolite repression 4 protein
, carbon catabolite repressor protein 4 homolog
, cytoplasmic deadenylase