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Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. Additionally we are shipping CD164 Molecule, Sialomucin Antibodies (57) and CD164 Molecule, Sialomucin Kits (3) and many more products for this protein.
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Endolyn is identified as an important gene for zebrafish pronephric kidney function.[Endolyn]
the deletion of the mssp gene results in both the growth defect in the embryo and the hormonal defect in adult female mouse.
MSSP is an important mediator for Fas (show FAS Proteins)-induced apoptosis in vivo and in vitro.
CD164 is a regulator of myoblast motility
CD164 expression may have affected the proliferation and apoptosis of human glioma cells via the PTEN/phosphoinositide 3-kinase/AKT (show AKT1 Proteins) pathway.
The expression of Sezary signature genes: FCRL3 (show FCRL3 Proteins), Tox (show TOX Proteins), and miR (show MLXIP Proteins)-214, was significantly higher in samples from Sezary syndrome patients with CD164 expressing CD4 (show CD4 Proteins)(+) T cells.
In a cohort of patients with Sezary syndrome, CD164 expression on total CD4 (show CD4 Proteins)+ lymphocytes was significantly upregulated compared with healthy controls. CD164 expression was in most cases limited to CD4 (show CD4 Proteins)+CD26 (show DPP4 Proteins)- malignant T lymphocytes.
This paper identified a new Deafness, Autosomal Dominant locus located on chromosome 6q15-21 and implicated CD164 as a novel gene for hearing impairment.
miR (show MLXIP Proteins)-219 inhibits the proliferation, migration and invasion of medulloblastoma cells by targeting CD164.
Increased expression of CD164 is involved in ovarian cancer progression via the SDF-1alpha/CXCR4 (show CXCR4 Proteins) axis.
CD164 is highly expressed in the colon cancer sites, and it promotes HCT116 colon cancer cell proliferation and metastasis both in vitro and in vivo
C-jun (show JUN Proteins) and HIF-1alpha (show HIF1A Proteins) bound to the CD164 promoter region and activated the CD164 expression.
Conclude that assessment of allergen-induced basophil CD164 upregulation is a very useful method for in vitro determination of allergy to grass pollens.
Review article on structure and function of CD164.
Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (Watt et al., 1998
CD164 antigen, sialomucin
, multi-glycosylated core protein 24
, sialomucin core protein 24
, MGC-24 protein
, CD164 molecule, sialomucin
, CD164 sialomucin-like 2
, CD164 antigen
, c-Myc binding protein