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CD1B encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. Additionally we are shipping CD1b Proteins (10) and CD1b Kits (1) and many more products for this protein.
Showing 10 out of 191 products:
Human Monoclonal CD1b Primary Antibody for IHC (fro), IF - ABIN1106010
Khalili-Shirazi, Gregson, Londei, Summers, Hughes: The distribution of CD1 molecules in inflammatory neuropathy. in Journal of the neurological sciences 1998
Show all 5 references for ABIN1106010
Human Monoclonal CD1b Primary Antibody for FACS, CyTOF - ABIN2664351
Hayes, Knight: Group 1 CD1 genes in rabbit. in Journal of immunology (Baltimore, Md. : 1950) 2001
The crystal structure of CD1b3 has been determined in complex with endogenous ligands, identified as a mixture of phosphatidylcholine (show SGMS1 Antibodies) and phosphatidylethanolamine, and the ability of the protein to bind mycobacterial glycolipids has been analyzed.
These results underscore substantial conservation of the group 1 CD1 system between humans and rhesus macaque monkeys.
the development of polyvalent complexes of CD1b proteins and carbohydrate backbones (dextramers) and their use in identifying CD1b autoreactive T cells from human donors.
[review] Humans express both Group 1 (CD1a (show CD1A Antibodies), CD1b and CD1c (show CD1C Antibodies)) and Group 2 (CD1d) CD1 (show KY Antibodies) molecules with nonredundant functions in response to the presentation of endogenous lipids.
for isoforms CD1b through CD1e (show CD1e Antibodies), our simulations show the near-complete collapse of the hydrophobic cavities in the absence of the antigen. This event results from the spontaneous closure of the binding domain entrance, flanked by two alpha-helices.
Dysregulated CD1 (show CD1A Antibodies) profile in myeloid dendritic cells in CVID (show TNFRSF13B Antibodies) is normalized by IVIg treatment.
Molecular mechanisms by which CD1b captures distinct classes of self- and mycobacterial antigens are reviewed. Review.
Deciphering the role of CD1e (show CD1e Antibodies) protein in mycobacterial phosphatidyl-myo (show SYNPO2 Antibodies)-inositol mannosides (PIM (show PIM1 Antibodies)) processing for presentation by CD1b to T lymphocytes
CD1b has a mechanism for presenting either two small or one large lipid, allowing presentation of antigens with an unusually broad range of chain lengths.
a cognate mechanism whereby CD1b-glycolipid complexes bind to TCRs.
The DC-SIGNlow/CD86high population is characterized by a reduced CD1b expression that correlates with a reduced iMtb-specific lymphocyte proliferation together with an enhanced mixed leukocyte reaction.
gammadelta T cells recognize lipid A (LA) in a CD1b- or CD1c (show CD1C Antibodies)-restricted manner in first response against Gram-bacteria, while the interaction between TLR4 (show TLR4 Antibodies) on gammadelta T cells and LA might strengthen the subsequent response of gammadelta T cells.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
, CD1b molecule
, T-cell surface glycoprotein CD1b-3
, T-cell surface glycoprotein CD1c
, T-cell surface glycoprotein CD1b
, CD1b antigen
, CD1B antigen, b polypeptide
, cortical thymocyte antigen CD1B
, differentiation antigen CD1-alpha-3