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CD1b Molecule Proteins (CD1B)

CD1B encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. Additionally we are shipping CD1b Antibodies (191) and CD1b Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD1B 910 P29016
CD1B 100037709  
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Top CD1b Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,146.83
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CD1B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,
Rabbit

Top referenced CD1b Proteins

  1. Human CD1b Protein expressed in Escherichia coli (E. coli) - ABIN1098219 : Shamshiev, Donda, Prigozy, Mori, Chigorno, Benedict, Kappos, Sonnino, Kronenberg, De Libero: The alphabeta T cell response to self-glycolipids shows a novel mechanism of CD1b loading and a requirement for complex oligosaccharides. in Immunity 2000 (PubMed)
    Show all 2 references for ABIN1098219

  2. Human CD1b Protein expressed in Human Cells - ABIN2004815 : Kereiakes, Topol, George, Abbottsmith, Stack, Candela, ONeill, Martin, Califf: Emergency coronary artery bypass surgery preserves global and regional left ventricular function after intravenous tissue plasminogen activator therapy for acute myocardial infarction. in Journal of the American College of Cardiology 1988 (PubMed)
    Show all 2 references for ABIN2004815

More Proteins for CD1b Molecule (CD1B) Interaction Partners

Cow (Bovine) CD1b Molecule (CD1B) interaction partners

  1. The crystal structure of CD1b3 has been determined in complex with endogenous ligands, identified as a mixture of phosphatidylcholine (show SGMS1 Proteins) and phosphatidylethanolamine, and the ability of the protein to bind mycobacterial glycolipids has been analyzed.

Rhesus Monkey CD1b Molecule (CD1B) interaction partners

  1. These results underscore substantial conservation of the group 1 CD1 system between humans and rhesus macaque monkeys.

Human CD1b Molecule (CD1B) interaction partners

  1. the development of polyvalent complexes of CD1b proteins and carbohydrate backbones (dextramers) and their use in identifying CD1b autoreactive T cells from human donors.

  2. [review] Humans express both Group 1 (CD1a, CD1b and CD1c) and Group 2 (CD1d) CD1 molecules with nonredundant functions in response to the presentation of endogenous lipids.

  3. for isoforms CD1b through CD1e (show CD1e Proteins), our simulations show the near-complete collapse of the hydrophobic cavities in the absence of the antigen. This event results from the spontaneous closure of the binding domain entrance, flanked by two alpha-helices.

  4. Dysregulated CD1 (show CD1A Proteins) profile in myeloid dendritic cells in CVID (show TNFRSF13B Proteins) is normalized by IVIg treatment.

  5. Molecular mechanisms by which CD1b captures distinct classes of self- and mycobacterial antigens are reviewed. Review.

  6. Deciphering the role of CD1e (show CD1e Proteins) protein in mycobacterial phosphatidyl-myo-inositol mannosides (PIM (show PIM1 Proteins)) processing for presentation by CD1b to T lymphocytes

  7. CD1b has a mechanism for presenting either two small or one large lipid, allowing presentation of antigens with an unusually broad range of chain lengths.

  8. a cognate mechanism whereby CD1b-glycolipid complexes bind to TCRs.

  9. The DC-SIGNlow/CD86high population is characterized by a reduced CD1b expression that correlates with a reduced iMtb-specific lymphocyte proliferation together with an enhanced mixed leukocyte reaction.

  10. gammadelta T cells recognize lipid A (LA) in a CD1b- or CD1c (show CD1C Proteins)-restricted manner in first response against Gram-bacteria, while the interaction between TLR4 (show TLR4 Proteins) on gammadelta T cells and LA might strengthen the subsequent response of gammadelta T cells.

CD1b (CD1B) Protein Profile

Protein Summary

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

Gene names and symbols associated with CD1b Molecule Proteins (CD1B)

  • CD1b molecule (CD1B)
  • CD1c molecule (CD1C)
  • T-cell surface glycoprotein CD1b1-like (LOC100720602)
  • CD1 protein
  • CD1-b protein
  • CD1A protein
  • CD1B protein
  • CD1B3 protein
  • R1 protein

Protein level used designations for CD1b Molecule Proteins (CD1B)

CD1b3 , CD1b molecule , T-cell surface glycoprotein CD1b-3 , T-cell surface glycoprotein CD1c , T-cell surface glycoprotein CD1b , CD1b antigen , CD1B antigen, b polypeptide , cortical thymocyte antigen CD1B , differentiation antigen CD1-alpha-3

GENE ID SPECIES
509004 Bos taurus
443423 Ovis aries
457420 Pan troglodytes
488609 Canis lupus familiaris
718955 Macaca mulatta
100034038 Equus caballus
100174779 Canis lupus familiaris
100599192 Nomascus leucogenys
910 Homo sapiens
100037709 Oryctolagus cuniculus
100720602 Cavia porcellus
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