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CD1d Molecule Proteins (CD1D)

CD1D encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. Additionally we are shipping CD1d Antibodies (192) and CD1d Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD1D 912 P15813
CD1D 12479 P11609
CD1D 25109 Q63493
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Top CD1d Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$841.50
Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Sylvilagus floridanus His tag   1 mg Log in to see 56 to 66 Days
$2,718.83
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,740.83
Details

CD1D Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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More Proteins for CD1d Molecule (CD1D) Interaction Partners

Cow (Bovine) CD1d Molecule (CD1D) interaction partners

  1. Data indicate that bovine CD1d is able to bind glycosphingolipids (GSLs) with fatty acid chain lengths of C18 (show BBS9 Proteins), while GSLs with fatty acids of C24 do not bind.

Rhesus Monkey CD1d Molecule (CD1D) interaction partners

  1. The expression profile of CD1d mRNA in Rhesus macaque is in accordance with the tissue distribution and the functions of NKT (show SLC22A6 Proteins) cells in other species.

Human CD1d Molecule (CD1D) interaction partners

  1. Data suggest that CD1d antigen-restricted B lymphocytes (Bc) presentation of NGcGM3 drives effective invariant natural killer T cells (iNKT) activation.

  2. the spatiotemporal distribution of CD1d molecules on the surface of antigen-presenting cells (APCs (show APCS Proteins)) modulates activation of Invariant natural killer T cells.

  3. both membrane-bound (V4) and soluble (V5) isoforms of CD1d were over-expressed in gastric tumor tissues, suggesting that they are involved in anti-tumor immune responses.

  4. This suggests that CD1D is more polymorphic than previously assumed

  5. by controlling a fundamental step in CD1d-mediated lipid antigen presentation, STAT3 (show STAT3 Proteins) signalling promotes innate immune responses driven by CD1d

  6. CD1d acts as a cell surface receptor that recognizes and binds oxysterols and initializes a pathway connecting oxysterol binding to PPARgamma (show PPARG Proteins) activation

  7. Using diffraction-based dotReadytrade mark immunoassays, the present study showed that staphylococcal enterotoxin B directly and specifically conjugated to CD1d.

  8. High CD1d expression is associated with medulloblastomas.

  9. our results demonstrate that both Ets1 (show ETS1 Proteins) and miR (show MLXIP Proteins)-155 can directly regulate the expression of CD1d on B-cells

  10. Ablation of this phosphorylation abolished herpes simplex virus 1 US3-mediated downregulation of CD1d expression, suggesting that phosphorylation of KIF3A (show KIF3A Proteins) is the primary mechanism of viral suppression of CD1d expression.

Mouse (Murine) CD1d Molecule (CD1D) interaction partners

  1. regulatory and protective role of CD1d-dependent natural killer T cells in contact hypersensitivity, at least in part via regulation of IL-10 (show IL10 Proteins) producing B(regs)

  2. The findings support a model in which low endosomal pH controls stability and lipid raft localization of CD1d-glycolipid complexes to regulate the outcome of iNKT cell mediated responses.

  3. affects iNKT cell activation by mast cells and release of both IFN-gamma (show IFNG Proteins) and IL-13 (show IL13 Proteins)

  4. CD1d acts as a cell surface receptor that recognizes and binds oxysterols and initializes a pathway connecting oxysterol binding to PPARgamma (show PPARG Proteins) activation

  5. Our results indicate that genetically controlled physiological variation of CD1d expression levels modulates iNKT-cell development.

  6. our results demonstrate that both Ets1 (show ETS1 Proteins) and miR (show MLXIP Proteins)-155 can directly regulate the expression of CD1d on B-cells

  7. We report a novel dichotomous role of beta2m and CD1d, whereby these molecules differently regulate autoimmunity against phospholipid versus non-phospholipid autoantigens.

  8. CD1d is up-regulated in early adipogenesis, and is transcriptionally controlled by CCAAT/enhancer-binding protein (C/EBP)-beta (show CEBPB Proteins) and -delta.

  9. these results suggest that the canonical TGF-beta (show TGFB1 Proteins)/Smad (show SMAD1 Proteins) pathway negatively regulates an important arm of the host's innate immune responses - CD1d-mediated lipid antigen presentation to NKT (show CTSL1 Proteins) cells.

  10. These results demonstrate that Bcl-xL (show BCL2L1 Proteins) regulates CD1d-mediated Ag processing and presentation to NKT (show CTSL1 Proteins) cells by altering the late endosomal compartment and changing the intracellular localization of CD1d.

CD1d (CD1D) Protein Profile

Protein Summary

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.

Gene names and symbols associated with CD1d Molecule Proteins (CD1D)

  • CD1d molecule (CD1D)
  • CD1c molecule (CD1C)
  • CD1D antigen, d polypeptide (CD1D)
  • CD1d1 antigen (Cd1d1)
  • CD1d1 molecule (Cd1d1)
  • AI747460 protein
  • Cd1 protein
  • CD1.1 protein
  • CD1.2 protein
  • Cd1a protein
  • Cd1d protein
  • CD1D1 protein
  • Ly-38 protein
  • R3 protein

Protein level used designations for CD1d Molecule Proteins (CD1D)

antigen-presenting glycoprotein CD1d , CD1-1 antigen , CD1D antigen, d polypeptide , CD1d molecule , d polypeptide , HMC class I antigen-like glycoprotein CD1D , R3G1 , T-cell surface glycoprotein CD1d , differentiation antigen CD1-alpha-3 , thymocyte antigen CD1D , T-cell surface glycoprotein CD1d1 , antigen-presenting glycoprotein CD1d1 , CD1D antigen , CD1d1 antigen

GENE ID SPECIES
100301530 Oryctolagus cuniculus
425801 Gallus gallus
516046 Bos taurus
613268 Macaca mulatta
912 Homo sapiens
100144424 Ovis aries
469524 Pan troglodytes
12479 Mus musculus
25109 Rattus norvegicus
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