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CD2BP2 encodes a bi-functional protein. Additionally we are shipping CD2 (Cytoplasmic Tail) Binding Protein 2 Antibodies (44) and and many more products for this protein.
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CD2BP2 is the ligand of the membrane-proximal proline-rich tandem repeat of CD2 (show CD2 Proteins) in detergent-soluble membrane compartments.
there is a function of the GYF domain of CD2BP2 in mediating protein-protein interactions within the spliceosome
interaction of CD2BP2 with a tri (show VANGL2 Proteins)-snRNP (show LSM2 Proteins) bridging protein (Prp6 (show PRPF6 Proteins)), coupled with CD2BP2's absence from the tri (show VANGL2 Proteins)-snRNP (show LSM2 Proteins), suggests it might function in tri (show VANGL2 Proteins)-snRNP (show LSM2 Proteins) assembly
findings indicate that CD2BP2 is not a constitutive binding partner or key regulator of CD2 (show CD2 Proteins)-mediated signaling events
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
CD2 antigen (cytoplasmic tail) binding protein 2
, CD2 antigen cytoplasmic tail-binding protein 2
, CD2 cytoplasmic domain-binding protein 2
, U5 snRNP 52K protein
, protein phosphatase 1, regulatory subunit 59
, CD2 tail-binding protein 2