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CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). Additionally we are shipping CD2 Antibodies (858) and CD2 Kits (14) and many more products for this protein.
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Ptpn22 (show PTPN22 Proteins) and Cd2 (show CCND2 Proteins) Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes
CD2 (show CCND2 Proteins) stimuli were mandatory for Treg cell survival with reduced Bim (show BCL2L11 Proteins) expression, but CD2 (show CCND2 Proteins) may not function as a direct receptor for molecules on stromal cells.
CD2 (show CCND2 Proteins) is important for the efficient development of CD4 (show CD4 Proteins) single-positive thymocytes and TCR-dependent activation of mature CD4 (show CD4 Proteins) lymph node T cells, but does not direct a particular helper T cell subset polarity.
molecular mechanism of heterophilic adhesion between the murine T-cell adhesion glycoprotein (show CD226 Proteins) CD2 (show CCND2 Proteins) and its ligand CD48 (show CD48 Proteins)
Despite normal T cell numbers, mice deficient in the costimulatory molecules CD2 (show CCND2 Proteins) and CD28 (show CD28 Proteins) spontaneously develop Pneumocystis carinii pneumonia.
autoimmunity may be mediated by a combination of genes in the SLAM (show SLAMF1 Proteins)/CD2 (show CCND2 Proteins) family cluster
Analysis of the ligand-receptor pairs involved in induction of germline transcripts (Igamma2a) necessary for switch recombination revealed that expression of CD48 (show CD48 Proteins) on B cells and ligands CD2 (show CCND2 Proteins) and CD244 (show CD244 Proteins) on NK cells are able to stimulate Igamma2a
CD2 (show CCND2 Proteins) deficient mice are more resistant to T. gondii infection than wild type mice
nanoscale increases in CD2 (show CCND2 Proteins)-CD48 (show CD48 Proteins)-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse
CD244 (show CD244 Proteins) inhibition and activation depends on CD2 (show CCND2 Proteins) and phospholipase C (show PLC Proteins)-gamma1
These results reveal an unexpected redundancy in the human NK cell response to human cytomegalovirus and suggest that CD2 provides "signal 2" in antibody-driven adaptive NK cell responses.
Establish CD2 as a new susceptibility factor for systemic sclerosis in a European Caucasian population.
the fundamental mechanism of glycosylation of human CD2 is to promote CD2-CD58 (show CD58 Proteins) binding by conformational adjustment of CD2
CD58 (show CD58 Proteins)/CD2 is the primary costimulatory pathway in human CD28 (show CD28 Proteins)-CD8 (show CD8A Proteins)+ T cells.
Both the mRNA expression levels and protein expression levels of HSP27 (show HSPB1 Proteins) were increased in astrocytes from POAG patients compared with those from normal control, suggesting that mutation in CD2 might pose a risk for POAG in Chinese population.
Although sMCs displayed immunoreactivity for one of the neoplastic antigens in the majority of SM patients, the aberrant CD2 and/or CD25 (show IL2RA Proteins) expression on sMCs is not as indicative of SM as the BMMC immunophenotype.
ERGdel may be a pure surrogate of CD2-positivity--which has been suggested to be a good prognositc marker in childhood ALL
Altogether, these results show that a high CD2 expression level is a hallmark of latently infected resting memory CD4 (show CD4 Proteins)(+) T cells in vivo.
Aberrant CD2 expression appears to further determine a shorter progression free survival
CD2-CD58 (show CD58 Proteins)/48 receptor-ligand interaction promotes and is required for nanotube formation in human natural killer cells.
CD2- gammadelta T cells showed CD2 de novo expression after ConA/IL-2 (show IL2 Proteins)/IL-12 (show IL12A Proteins)/IL-18 (show IL18 Proteins) stimulation.
Porcine gamma-delta T lymphocytes can be categorized into two functionally and developmentally distinct subsets according to expression of CD2 and level of TCR.
CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986
CD2 antigen (p50), sheep red blood cell receptor
, T-cell surface antigen CD2
, cluster of differentiation 2
, CD2 antigen
, CD2 molecule
, LFA-3 receptor
, T-cell surface antigen T11/Leu-5
, lymphocyte antigen 37
, erythrocyte receptor
, lymphocyte-function antigen-2
, rosette receptor
, OX-34 antigen
, OX-45 surface antigen homolog to human T lymphocyte CD2 antigen
, T-lymphocyte surface antigen precursor CD2