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CD2-Associated Protein Proteins (Cd2ap)

Cd2ap encodes a scaffolding molecule that regulates the actin cytoskeleton. Additionally we are shipping CD2-Associated Protein Antibodies (40) and CD2-Associated Protein Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Cd2ap 23607 Q9Y5K6
Cd2ap 12488 Q9JLQ0
Cd2ap 316258  
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Top CD2-Associated Protein Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$795.30
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

Cd2ap Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for CD2-Associated Protein (Cd2ap) Interaction Partners

Human CD2-Associated Protein (Cd2ap) interaction partners

  1. Study found a novel association of CD2AP with plasma homocysteine in participants with African ancestry and found a new variant in the candidate gene CBS (show CBS Proteins) associated with homocysteine

  2. CD2AP rs9349407 polymorphism contributes to Alzheimer's disease susceptibility.

  3. discovered novel interaction candidates for CD2AP and characterized subtle yet significant differences in the recognition preferences of its three SH3 domains for c-CBL (show CBL Proteins), ALIX (show PDCD6IP Proteins), and RIN3 (show RIN3 Proteins)

  4. we present the first demonstration that the purified SH3 domains of the CD2AP/Cin85 (show SH3KBP1 Proteins) protein family are able to directly bind the p53 (show TP53 Proteins) protein, and to discriminate between the two polymorphic variants P72R

  5. CD2-Associated Protein affects Abeta (show APP Proteins) levels and Abeta42/Abeta40 ratio in vitro

  6. CD2AP gene variants may contribute to susceptibility to end-stage renal disease in patients with type 1 diabetes.

  7. FSGS3/CD2AP has a role of barbed-end capping in junctional actin dynamics.

  8. an FRS2beta (show FRS3 Proteins)-CIN85 (show SH3KBP1 Proteins)/CD2AP-Cbl (show CBL Proteins) axis for downregulation of ErbB2 (show ERBB2 Proteins) may regulate ErbB2 (show ERBB2 Proteins) protein levels in physiological and pathological settings

  9. E2F1 (show E2F1 Proteins) up-regulates the human CD2AP promoter.

  10. CD2AP is highly expressed in human plasmacytoid dendritic cells (DC) and positively regulates blood DC antigen 2 (BDCA2)/Fc fragment of IgE high affinity I receptor (FcepsilonR1gamma) signaling.

Mouse (Murine) CD2-Associated Protein (Cd2ap) interaction partners

  1. CD2AP forms a complex with GGA2 (show GGA2 Proteins), a clathrin adaptor, which sorts Glut4 (show SLC2A4 Proteins) to GSVs, suggesting a role for CD2AP in this process.

  2. CD2AP is the first signaling molecule associated with adult sensory axonal collateral sprouting

  3. CD2AP has role in mediating blood-brain barrier integrity and cerebrovascular roles of CD2AP could contribute to its effects on Alzheimer's disease risk.

  4. CD2-Associated Protein affects Abeta (show APP Proteins) levels and Abeta42/Abeta40 ratio in vitro

  5. only the SH3 domains of CD2AP are necessary to enhance the E3 ligase activity of Cbl-3 (show CBLC Proteins)/c toward Ret51 (show RET Proteins)

  6. CD2AP is not involved in the regulation of type I IFNs in plasmacytoid dendritic cells. Its major function is on the actin cytoskeleton, affecting migration to local lymph nodes under conditions of inflammation.

  7. CD2AP deficiency results in the excretion of intact albumin (show ALB Proteins) in knockout mice.

  8. the formation of lamellipodia is mediated by a complex of cortactin (show CTTN Proteins), CD2AP, and actin capping protein (show TMOD4 Proteins)

  9. These data descrived the importance of concomitant decreases in podocin, CD2AP and tensin2 during septic acute renal failure-associated proteinuria.

  10. Sh3kbp1 (show SH3KBP1 Proteins) is SUMOylated by SUMO-1 (show SUMO1 Proteins), -2, and -3 and that SUMOylation is enhanced in the presence of Cd2ap.

CD2-Associated Protein (Cd2ap) Protein Profile

Protein Summary

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Gene names and symbols associated with CD2-Associated Protein Proteins (Cd2ap)

  • CD2-associated protein (cd2ap)
  • CD2-associated protein (CD2AP)
  • CD2-associated protein (Cd2ap)
  • AL024079 protein
  • C78928 protein
  • cd2apl protein
  • CMS protein
  • DKFZp469E061 protein
  • fj51c01 protein
  • im:7153970 protein
  • METS-1 protein
  • Mets1 protein
  • si:ch211-207n9.1 protein
  • wu:fj51c01 protein
  • zgc:103705 protein

Protein level used designations for CD2-Associated Protein Proteins (Cd2ap)

CD2-associated protein , Cas ligand with multiple Src homology 3 (SH3) domains , adapter protein CMS , cas ligand with multiple SH3 domains , hypothetical protein , SH3 domain-containing adapter protein , SH3 domain-containing adaptor protein METS-1 , mesenchyme to epithelium transition protein, SH3 domains , mesenchyme-to-epithelium transition protein with SH3 domains 1

GENE ID SPECIES
445851 Xenopus laevis
472241 Pan troglodytes
494040 Danio rerio
705221 Macaca mulatta
100014892 Monodelphis domestica
100158527 Xenopus (Silurana) tropicalis
100172673 Pongo abelii
100341696 Oryctolagus cuniculus
100386627 Callithrix jacchus
100466982 Ailuropoda melanoleuca
100554210 Anolis carolinensis
100600076 Nomascus leucogenys
23607 Homo sapiens
771715 Gallus gallus
474928 Canis lupus familiaris
533188 Bos taurus
12488 Mus musculus
316258 Rattus norvegicus
100731393 Cavia porcellus
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