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CD207 Molecule, Langerin Proteins (CD207)

The protein encoded by CD207 is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. Additionally we are shipping CD207 Antibodies (110) and CD207 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD207 246278 Q8VBX4
CD207 50489 Q9UJ71
Rat CD207 CD207 502852  
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Top CD207 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Human Cells Cynomolgus Fc Tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CD207 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, ,

More Proteins for CD207 Molecule, Langerin (CD207) Interaction Partners

Mouse (Murine) CD207 Molecule, Langerin (CD207) interaction partners

  1. Data show that Candida albicans and Candida tropicalis preferentially localized in (and persisted within) a sub- population of Peyer's patch Langerin-positive dendritic cells.

  2. Langerin is expressed by the XCR1(+) "DC1" populat (show CD1C Proteins)ion of mice.

  3. Langerin+ dermal dendritic cells appear to be site- and strain-specific

  4. TLR7 (show TLR7 Proteins)-activated langerin(neg) dendritic cells trigger psoriatic plaque formation via IL-23 (show IL23A Proteins)-mediated activation of innate IL-17 (show IL17A Proteins)/IL-22 (show IL22 Proteins)-producing lymphocytes, independently of IFN-I.

  5. model of epicutaneous ovalbumin (show OVA Proteins) sensitization inducing an inflammatory skin resembling atopic dermatitis (AD) to explore the role of CD207 in the pathogenesis of AD

  6. Langerin-positive dendritic cells appear to be the predominant, though not exclusive, population responsible for in vivo transport of anti-DEC-205 (show LY75 Proteins) antibodies from the skin to the draining lymph nodes in steady state and inflammation.

  7. Data demonstrated that CD207(+) CD8alpha(+) thymic DCs do not share a common origin with T cells but originate from intrathymic precursors.

  8. The normal corneal epithelium is endowed with CD11c (show ITGAX Proteins)(+) Langerin+ cells that are LCs, whereas the stroma is endowed with a separate population of (non-LC) Langerin+ DCs.

  9. Comparable T helper 1 (Th1 (show HAND1 Proteins)) and CD8 (show CD8A Proteins) T-cell immunity by targeting HIV gag p24 to CD8 (show CD8A Proteins) dendritic cells within antibodies to Langerin, DEC205 (show LY75 Proteins), and Clec9A (show CLEC9A Proteins).

  10. Langerhan cells and (Langerin(+)) dermal dendritic cells thus seem to have a redundant function in regulating contact hypersensitivity

Human CD207 Molecule, Langerin (CD207) interaction partners

  1. This study shows that mutations in the Langerin gene are present in the analysed populations at different genotypic and allelic frequencies and further studies should be conducted to verify the role of these mutations in HIV-1 susceptibility.

  2. This study is the first to demonstrate that langerin represents an authentic receptor that binds and internalizes influenza A virus to facilitate infection.

  3. Data suggest that Langerin (CD207)-mediated binding of Yersinia pestis to antigen-presenting cells (APCs (show APCS Proteins)) may promote its dissemination and infection.

  4. Langerin binds heparin (HEP)-like oligosaccharides in two different binding sites depending on the ligand size.

  5. The authors not only show that langerin and caveolin-1 (show CAV1 Proteins) co-localize at the cell membrane and in vesicles but that caveolin-1 (show CAV1 Proteins) mediated HIV-1 uptake is an intrinsic restriction mechanism present in human Langerhans cells that prevents HIV-1 infection.

  6. The impact of two carbohydrate recognition domains mutations, W264R and F241L, on langerin structure, function, and Birbeck granules assembly.

  7. Langerin is not expressed by freshly isolated CD1c (show CD1C Proteins)(+) blood DCs but is rapidly induced on CD1c (show CD1C Proteins)(+) DCs by serum or TGF-beta (show TGFB1 Proteins) via an ALK-3 (show BMPR1A Proteins)-dependent pathway.

  8. Cell-sorting experiments demonstrated that IDO1 (show IDO1 Proteins) expression is found in a subset of CD1a (show CD1A Proteins)(+)CD14 (show NDUFA2 Proteins)(-)langerin(+) cells, expressing CD103 (show ITGAE Proteins)

  9. However, the superoxide dismutase (show SOD1 Proteins) C (SodC (show SOD1 Proteins)) protein of the Mycobacterium leprae cell wall was identified as a langerin-reactive ligand.

  10. Both phases of HIV transfer from eLCs to T cells were inhibited when eLCs were pretreated with a mAb to langerin CRD (show CRX Proteins) or when HIV was pretreated with a soluble langerin trimeric extracellular domain or by a CRD (show CRX Proteins) homolog.

CD207 Protein Profile

Protein Summary

The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.

Gene names and symbols associated with CD207

  • CD207 molecule, langerin (CD207)
  • CD207 antigen (Cd207)
  • CD207 molecule, langerin (Cd207)
  • CD207 protein
  • CLEC4K protein
  • RGD1565913 protein

Protein level used designations for CD207

CD207 molecule, langerin , CD207 antigen, langerin , C-type lectin domain family 4 member K , Langerhans cell specific c-type lectin , langerin , C-type lectin domain family 4, member K , CD 207 antigen

GENE ID SPECIES
511000 Bos taurus
703420 Macaca mulatta
737419 Pan troglodytes
100580491 Nomascus leucogenys
246278 Mus musculus
50489 Homo sapiens
100037935 Sus scrofa
502852 Rattus norvegicus
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