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CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) ELISA Kits

CD244 encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. Additionally we are shipping CD244 Antibodies (127) and CD244 Proteins (23) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CD244 51744 Q9BZW8
CD244 64025 Q9JLM2
CD244 18106 Q07763
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Top CD244 ELISA Kits at antibodies-online.com

Showing 3 out of 8 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 10pg/mL 62.5-4000 pg/mL Human CD244/2B4 PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$369.00
Details
Mouse 7.81 pg/ml 2000-31.25 pg/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details
Rat 7.81 pg/ml 2000-31.25 pg/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details

Top referenced CD244 ELISA Kits

  1. Human CD244 ELISA Kit for Sandwich ELISA - ABIN1672841 : Benoit, Wang, Pabst, Dutz, Tan: Defective NK cell activation in X-linked lymphoproliferative disease. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 3 references for ABIN1672841

More ELISA Kits for CD244 Interaction Partners

Human CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) interaction partners

  1. SLAMF4 gene and surface protein expression was down-regulated in CD8 (show CD8A ELISA Kits)+ T cells from SLE patients compared with that in cells obtained from healthy donors. SLAMF4+ effector memory cells produced more granzyme B (show Gzmb ELISA Kits) and perforin (show PRF1 ELISA Kits) than SLAMF4- cells.

  2. GSK-3 undergoes inhibitory phosphorylation at regulatory serine residues by the engagement of NKG2D (show KLRK1 ELISA Kits) and 2B4, either individually or in combination.

  3. Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8 (show CD8A ELISA Kits)+ T Cell Hyporesponsiveness to Alloantigen

  4. CD8 (show CD8A ELISA Kits)(+) T cells require 2B4 for Epstein-Barr virus-specific immune control, because 2B4 blockade after CD8 (show CD8A ELISA Kits)(+) T-cell depletion did not further aggravate symptoms of the infection.

  5. CD244 expression/signaling in tuberculosis correlates with high levels of a long noncoding RNA (lncRNA)-BC050410 [named as lncRNA-AS-GSTT1(1 (show GSTT1 ELISA Kits)-72) or lncRNA-CD244] in the CD244(+)CD8 (show CD8A ELISA Kits)(+) T-cell subpopulation.

  6. show that in addition to NKG2D (show KLRK1 ELISA Kits), human CEACAM1 (show CEACAM1 ELISA Kits) can inhibit NK-cell activation via NKp30 (show NCR3 ELISA Kits) or 2B4

  7. this study investigates the structural requirements for the recruitment of the human-activating NK-cell receptors NKG2D (show KLRK1 ELISA Kits) and 2B4 to detergent-resistant membrane fractions in the murine BA/F3 cell line and in the human NK-cell line NKL (show GLIS2 ELISA Kits).

  8. Study of SAP (show APCS ELISA Kits) expression is specific but may have insufficient sensitivity for screening XLP1 as a single tool; however, combination with 2B4 functional assay allows identification of all cases

  9. Blockade of 2B4/CD48 (show CD48 ELISA Kits) interaction resulted in improvement in function via perforin (show PRF1 ELISA Kits) expression and degranulation as measured by CD107a (show LAMP1 ELISA Kits) surface mobilization on HTLV-1 specific CD8 (show CD8A ELISA Kits)+ T cells.

  10. In patients suffering from X-linked lymphoproliferative disease (XLP1), SAP (show APCS ELISA Kits) is nonfunctional, not only abolishing the activating function of 2B4, but rendering this receptor inhibitory.

Mouse (Murine) CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) interaction partners

  1. 2B4 dampens T-independent B cell responses.

  2. DCs from CD244(-/-) mice elicited increased NK cell activation in vitro. These data add CD244 to a growing list of immuno-modulatory receptors found on DCs.

  3. Data show that enforced expression of inhibitor of differentiation protein Id3 (show ID3 ELISA Kits) specifically increased the persistence of Cd244 protein 2B4(+) virus-specific CD8 (show CD8A ELISA Kits)(+) T cells.

  4. Molecular dynamic simulation explains unbinding and unfolding of CD48 (show CD48 ELISA Kits)-2B4 protein complexes.

  5. Signaling via SLAMF4 controls expansion of cytotoxic CD8alphabeta(+) IELs, which regulate the reversible depletion of lamina propria phagocytes and inflammation in the small intestine.

  6. CD244 (2B4) has a regulatory effect on mast cells and eosinophils in murine allergic inflammation.

  7. NKG2D (show KLRK1 ELISA Kits) ligation relieves 2B4-mediated NK-cell self-tolerance in mice.

  8. blockade of CD28 (show CD28 ELISA Kits) signals in the presence of preserved CTLA-4 (show CTLA4 ELISA Kits) signals results in the unique up-regulation of 2B4 on primary CD8 (show CD8A ELISA Kits)(+) effectors, and that this 2B4 expression plays a critical functional role in controlling antigen-specific T8 cell responses

  9. In the absence of SAP (show APCS ELISA Kits), signaling through the SLAM (show SLAMF1 ELISA Kits) family members Ly108 (show SLAMF6 ELISA Kits) and 2B4 resulted in increased recruitment of the SHP-1 (show PTPN6 ELISA Kits) phosphatase, associated with altered SHP-1 (show PTPN6 ELISA Kits) localization and decreased activation of Src (show SRC ELISA Kits) kinases at the synapse.

  10. Ox-LDL significantly promoted the interaction of natural killer cells and dendritic cells via CD48 (show CD48 ELISA Kits)-2B4 contact-dependent mechanisms.

CD244 Antigen Profile

Antigen Summary

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD244

  • CD244 molecule, natural killer cell receptor 2B4 (CD244) antibody
  • Cd244 molecule, natural killer cell receptor 2B4 (Cd244) antibody
  • CD244 natural killer cell receptor 2B4 (Cd244) antibody
  • 2B4 antibody
  • C9.1 antibody
  • CD244 antibody
  • F730046O15Rik antibody
  • Ly90 antibody
  • NAIL antibody
  • NKR2B4 antibody
  • Nmrk antibody
  • SLAMF4 antibody

Protein level used designations for CD244

CD244 molecule, natural killer cell receptor 2B4 , natural killer cell receptor 2B4 , NK cell activation inducing ligand NAIL , NK cell activation-inducing ligand , NK cell type I receptor protein 2B4 , SLAM family member 4 , h2B4 , signaling lymphocytic activation molecule 4 , CD244 natural killer cell receptor 2B4 , NKR2B4 , non MHC restricted killing associated , non-MHC restricted killing associated , transmembrane NK cell receptor 2B4 , NK cell receptor 2B4

GENE ID SPECIES
488644 Canis lupus familiaris
513468 Bos taurus
100594419 Nomascus leucogenys
51744 Homo sapiens
64025 Rattus norvegicus
18106 Mus musculus
Selected quality suppliers for CD244 (CD244) ELISA Kits
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