anti-CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) Antibodies

CD244 encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. Additionally we are shipping CD244 Proteins (27) and CD244 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD244 51744 Q9BZW8
CD244 64025 Q9JLM2
CD244 18106 Q07763
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Top anti-CD244 Antibodies at antibodies-online.com

Showing 10 out of 128 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p) A549 cells probed with Rabbit Anti-CD244 Polyclonal Antibody (ABIN740730) at 1:50 for 60 minutes followed by incubation with Goat Anti-Rabbit IgG FITC conjugated secondary at 1:100 (green) for 40 minutes compared to control cells (blue). Paraformaldehyde-fixed, paraffin embedded human kidney, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-CD244 Polyclonal Antibody, Unconjugated  at 1:200 overnight at 4°C, followed by a conjugated secondary for 90 minutes and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Mouse Un-conjugated FACS, IP Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD244: LOW ENDOTOXIN(ABIN120311). 0.5 mg Log in to see 6 to 8 Days
$632.50
Details
Human Mouse PE FACS   100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Goat PE FACS Detection of 2B4/CD244/SLAMF4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$267.75
Details
Mouse Goat Un-conjugated CyTOF, FACS, IHC, WB   100 μg Log in to see 8 to 9 Days
$372.75
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- CD244 antibody, IHC(P) IHC(P): Human Tonsil Tissue Anti- CD244 antibody, Western blotting All lanes: Anti CD244  at 0.5ug/ml Lane 1: MCF-7 Whole Cell Lysate at 40ug Lane 2: HELA Whole Cell Lysate at 40ug Predicted bind size: 42KD Observed bind size: 42KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Goat Un-conjugated EIA, IP, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Mouse Un-conjugated FACS, IP Flow Cytometry: 2B4/CD244/SLAMF4 Antibody (2B4.69) [ABIN2603879] - Staining of human peripheral blood lymphocytes with Mouse anti Human CD244. Flow Cytometry: 2B4/CD244/SLAMF4 Antibody (2B4.69) [ABIN2603879] - Staining of human peripheral blood lymphocytes with Mouse anti Human CD244: Low Endotoxin 0.1 mg Log in to see 7 to 9 Days
$408.19
Details

CD244 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CD244 Antibodies

  1. Human Monoclonal CD244 Primary Antibody for FACS - ABIN2689111 : Mathew, Garni-Wagner, Land, Takashima, Stoneman, Bennett, Kumar: Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells. in Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal CD244 Primary Antibody for FACS - ABIN2479428 : Gluckman, Jolivet, Scrobohaci, Devergie, Traineau, Bourdeau-Esperou, Lehn, Faure, Drouet: Use of prostaglandin E1 for prevention of liver veno-occlusive disease in leukaemic patients treated by allogeneic bone marrow transplantation. in British journal of haematology 1990 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal CD244 Primary Antibody for FACS, IP - ABIN2479426 : Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CD244 Primary Antibody for FACS, IP - ABIN2479430 : Raziorrouh, Schraut, Gerlach, Nowack, Grüner, Ulsenheimer, Zachoval, Wächtler, Spannagl, Haas, Diepolder, Jung: The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function. in Hepatology (Baltimore, Md.) 2010 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal CD244 Primary Antibody for FACS - ABIN2479431 : Bengsch, Martin, Thimme: Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation. in Journal of hepatology 2014 (PubMed)
    Show all 4 Pubmed References

  6. Mouse (Murine) Polyclonal CD244 Primary Antibody for FACS, IHC - ABIN4898999 : Cao, Wagers, Karsunky, Zhao, Reeves, Wong, Stevenson, Weissman, Contag: Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors. in Blood 2008 (PubMed)

  7. Human Polyclonal CD244 Primary Antibody for FACS - ABIN4895306 : Mattiola, Pesant, Tentorio, Molgora, Marcenaro, Lugli, Locati, Mavilio: Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

  8. Mouse (Murine) Polyclonal CD244 Primary Antibody for CyTOF, FACS - ABIN4899297 : Wahle, Paraiso, Kendig, Lawrence, Chen, Wu, Kerr: Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)

  9. Human Polyclonal CD244 Primary Antibody for IHC (p) - ABIN740730 : Peiffer, Wang, Zimmerman, Ransom, Carmella, Kuo, Chen, Oshima, Huang, Hecht, Stoner: Dietary Consumption of Black Raspberries or Their Anthocyanin Constituents Alters Innate Immune Cell Trafficking in Esophageal Cancer. in Cancer immunology research 2016 (PubMed)

More Antibodies against CD244 Interaction Partners

Human CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) interaction partners

  1. 2B4 expression is increased on CD4 (show CD4 Antibodies)+ T cells in septic patients

  2. Self-iNKR(-) NK cells in X-linked lymphoproliferative disease 1 patients are functional even in resting conditions, suggesting a role of the inhibitory 2B4/CD48 (show CD48 Antibodies) pathway in the education process during NK-cell maturation.

  3. our results provide strong evidence that CD244 co-operates with c-Kit (show KIT Antibodies) to regulate leukemogenesis through SHP-2 (show PTPN11 Antibodies)/p27 (show PAK2 Antibodies) signaling.

  4. SLAMF4 gene and surface protein expression was down-regulated in CD8 (show CD8A Antibodies)+ T cells from SLE patients compared with that in cells obtained from healthy donors. SLAMF4+ effector memory cells produced more granzyme B (show Gzmb Antibodies) and perforin (show PRF1 Antibodies) than SLAMF4- cells.

  5. GSK-3 (show GSK3b Antibodies) undergoes inhibitory phosphorylation at regulatory serine residues by the engagement of NKG2D (show KLRK1 Antibodies) and 2B4, either individually or in combination.

  6. Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8 (show CD8A Antibodies)+ T Cell Hyporesponsiveness to Alloantigen

  7. CD8 (show CD8A Antibodies)(+) T cells require 2B4 for Epstein-Barr virus-specific immune control, because 2B4 blockade after CD8 (show CD8A Antibodies)(+) T-cell depletion did not further aggravate symptoms of the infection.

  8. CD244 expression/signaling in tuberculosis correlates with high levels of a long noncoding RNA (lncRNA)-BC050410 [named as lncRNA-AS-GSTT1(1 (show GSTT1 Antibodies)-72) or lncRNA-CD244] in the CD244(+)CD8 (show CD8A Antibodies)(+) T-cell subpopulation.

  9. show that in addition to NKG2D (show KLRK1 Antibodies), human CEACAM1 (show CEACAM1 Antibodies) can inhibit NK-cell activation via NKp30 (show NCR3 Antibodies) or 2B4

  10. this study investigates the structural requirements for the recruitment of the human-activating NK-cell receptors NKG2D (show KLRK1 Antibodies) and 2B4 to detergent-resistant membrane fractions in the murine BA/F3 cell line and in the human NK-cell line NKL (show GLIS2 Antibodies).

Mouse (Murine) CD244 Molecule, Natural Killer Cell Receptor 2B4 (CD244) interaction partners

  1. 2B4 expression is increased on CD4 (show CD4 Antibodies)+ T cells in septic animals

  2. 2B4 dampens T-independent B cell responses.

  3. DCs from CD244(-/-) mice elicited increased NK cell activation in vitro. These data add CD244 to a growing list of immuno-modulatory receptors found on DCs.

  4. Data show that enforced expression of inhibitor of differentiation protein Id3 (show ID3 Antibodies) specifically increased the persistence of Cd244 protein 2B4(+) virus-specific CD8 (show CD8A Antibodies)(+) T cells.

  5. Molecular dynamic simulation explains unbinding and unfolding of CD48 (show CD48 Antibodies)-2B4 protein complexes.

  6. Signaling via SLAMF4 controls expansion of cytotoxic CD8alphabeta(+) IELs, which regulate the reversible depletion of lamina propria phagocytes and inflammation in the small intestine.

  7. CD244 (2B4) has a regulatory effect on mast cells and eosinophils in murine allergic inflammation.

  8. NKG2D (show KLRK1 Antibodies) ligation relieves 2B4-mediated NK-cell self-tolerance in mice.

  9. blockade of CD28 (show CD28 Antibodies) signals in the presence of preserved CTLA-4 (show CTLA4 Antibodies) signals results in the unique up-regulation of 2B4 on primary CD8 (show CD8A Antibodies)(+) effectors, and that this 2B4 expression plays a critical functional role in controlling antigen-specific T8 cell responses

  10. In the absence of SAP (show APCS Antibodies), signaling through the SLAM (show SLAMF1 Antibodies) family members Ly108 (show SLAMF6 Antibodies) and 2B4 resulted in increased recruitment of the SHP-1 (show PTPN6 Antibodies) phosphatase, associated with altered SHP-1 (show PTPN6 Antibodies) localization and decreased activation of Src (show SRC Antibodies) kinases at the synapse.

CD244 Antigen Profile

Protein Summary

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD244

  • CD244 molecule, natural killer cell receptor 2B4 (CD244) antibody
  • Cd244 molecule, natural killer cell receptor 2B4 (Cd244) antibody
  • CD244 natural killer cell receptor 2B4 (Cd244) antibody
  • 2B4 antibody
  • C9.1 antibody
  • CD244 antibody
  • F730046O15Rik antibody
  • Ly90 antibody
  • NAIL antibody
  • NKR2B4 antibody
  • Nmrk antibody
  • SLAMF4 antibody

Protein level used designations for CD244

CD244 molecule, natural killer cell receptor 2B4 , natural killer cell receptor 2B4 , NK cell activation inducing ligand NAIL , NK cell activation-inducing ligand , NK cell type I receptor protein 2B4 , SLAM family member 4 , h2B4 , signaling lymphocytic activation molecule 4 , CD244 natural killer cell receptor 2B4 , NKR2B4 , non MHC restricted killing associated , non-MHC restricted killing associated , transmembrane NK cell receptor 2B4 , NK cell receptor 2B4

GENE ID SPECIES
488644 Canis lupus familiaris
513468 Bos taurus
100594419 Nomascus leucogenys
51744 Homo sapiens
64025 Rattus norvegicus
18106 Mus musculus
Selected quality suppliers for anti-CD244 (CD244) Antibodies
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