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Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Additionally we are shipping PD-L1 Proteins (61) and PD-L1 Kits (28) and many more products for this protein.
Showing 10 out of 263 products:
Human Monoclonal PD-L1 Primary Antibody for FACS, IHC (p) - ABIN1449244
Mandavilli: Hormone in the hot seat. in Nature medicine 2006
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Human Polyclonal PD-L1 Primary Antibody for IF, IHC (p) - ABIN500467
Chentoufi, Kritzer, Tran, Dasgupta, Lim, Yu, Afifi, Jiang, Carpenter, Osorio, Hsiang, Nesburn, Wechsler, BenMohamed: The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism. in Journal of virology 2011
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Human Polyclonal PD-L1 Primary Antibody for EIA, WB - ABIN401427
Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004
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Human Monoclonal PD-L1 Primary Antibody for IHC (p), ELISA - ABIN1995635
Soliman, Khalil, Antonia: PD-L1 expression is increased in a subset of basal type breast cancer cells. in PLoS ONE 2014
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Human Polyclonal PD-L1 Primary Antibody for IHC, ELISA - ABIN185339
Thompson, Gillett, Cheville, Lohse, Dong, Webster, Krejci, Lobo, Sengupta, Chen, Zincke, Blute, Strome, Leibovich, Kwon: Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. in Proceedings of the National Academy of Sciences of the United States of America 2004
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Human Monoclonal PD-L1 Primary Antibody for FACS - ABIN2853592
del Rio, Rodriguez-Barbosa, Kremmer, Förster: CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells. in Journal of immunology (Baltimore, Md. : 1950) 2007
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Mouse (Murine) Monoclonal PD-L1 Primary Antibody for FACS - ABIN317020
Kanai, Totsuka, Uraushihara, Makita, Nakamura, Koganei, Fukushima, Akiba, Yagita, Okumura, Machida, Iwai, Azuma, Chen, Watanabe: Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2003
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Human Monoclonal PD-L1 Primary Antibody for FACS - ABIN1449174
Iwai, Okazaki, Nishimura, Kawasaki, Yagita, Honjo: Microanatomical localization of PD-1 in human tonsils. in Immunology letters 2002
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Blockade of TGFbeta (show TGFB1 Antibodies) downregulated PD-1 (show PDCD1 Antibodies) and PD-L1 expression and precipitated graft rejection.
Loss of Cdk5 (show CDK5 Antibodies) results in persistent expression of the PD-L1 transcriptional repressors, the interferon (show IFNA Antibodies) regulatory factors IRF2 (show IRF2 Antibodies) and IRF2BP2 (show IRF2BP2 Antibodies), which likely leads to reduced PD-L1 expression on tumors.
The endogenous PD-1 (show PDCD1 Antibodies)/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.
addition to inhibiting T cells, hepatic stellate cells (HSCs) concurrently inhibit B cells via PD-L1; this direct B cell-inhibitory activity of HSCs should contribute to the mechanism by which HSCs maintain the liver's immune homeostasis
The results demonstrated that blockade of PD-1 (show PDCD1 Antibodies)/B7H1 pathway could promote mouse NK cells to kill the GL261GSCs, and the PD-1 (show PDCD1 Antibodies)-inhibited NK cells could be a feasible immune therapeutic approach against Glioblastoma multiforme.
These findings provide evidence for a novel immune escape mechanism during acute retroviral infection based on PD-L1 expression levels on virus infected target cells
These results suggest a novel and specific role for PspA (show SFTPA1 Antibodies) in modulating immune responses against S. pneumoniae by regulating PD-L1 expression.
Upregulation of PD-1 (show PDCD1 Antibodies) and PD-L1 was associated with marked increases in GADD153 (show DDIT3 Antibodies) during myocardial ischemic reperfusion injury.
Breg cells can suppress through the PD-1 (show PDCD1 Antibodies)/PD-L1 pathway in limiting the differentiation and function of TFH cells
Programmed death 1 (show PDCD1 Antibodies)/programmed death ligand 1 pathway likely plays a crucial role in the mechanisms underlying spontaneous tolerization of B cells responding to ABO (show ABO Antibodies)-blood group (show DARC Antibodies) antigens in liver transplantation.
PD-L1 expression and HLA class I antigen (show MICA Antibodies) expression by ICC cells was observed in 8 and 11, respectively, of the 27 tumors analyzed.
Higher CD8 (show CD8A Antibodies)+ lymphocyte infiltration was related to lower PD-L1 expression and higher FOXP3 (show FOXP3 Antibodies)+ tumor-infiltrating lymphocyte infiltration in breast cancer
Genetic amplification of the PD-L1 gene was correlated with Non-Small Cell Lung Cancer.
High CD274 expression is correlated with glioblastoma.
IL-27 (show IL27 Antibodies) induced IDO (show IDO1 Antibodies) or PD-L1 expression in monocytes and in human PC3 (show PCSK1 Antibodies) prostate and A549 lung cancer cells
PD-L1 expression in neutrophils is elevated in patients with systemic lupus erythematosus.
Immune checkpoint inhibitors, particularly those targeting PD-1 (show PDCD1 Antibodies) and PD-L1 are clinically active for the treatment of lung cancer and represent an exciting step forward in lung cancer therapy.
Data show that the serum soluble programmed death-ligand 1 (sPD (show HOXD13 Antibodies)-L1) level is a valuable biomarker for predicting treatment response and an independent prognostic factor for progression free survival (PFS).
PD-L1 copy number gain is present in approximately five percent of non-small cell lung cancer with a slight preference to squamous cell carcinoma.
PD-L1 expression is frequently discordant between surgical resected and matched biopsy specimens and thus may be potentially misleading in defining the sensitivity to treatment with PD-L1 targeted therapy.
role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development
These data suggest that overexpression of PD-L1 and PD-L2 (show PDCD1LG2 Antibodies) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.
Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.
A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.
This study provides novel information for the understanding of signalling through PD-L1.
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
, CD274 antigen
, programmed cell death 1 ligand 1
, programmed cell death ligand 1
, B7 homolog 1
, PDCD1 ligand 1
, programmed death ligand 1