anti-CD274 Molecule (CD274) Antibodies

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Additionally we are shipping PD-L1 Proteins (83) and PD-L1 Kits (47) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD274 60533 Q9EP73
CD274 29126 Q9NZQ7
CD274 499342  
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Top anti-PD-L1 Antibodies at antibodies-online.com

Showing 10 out of 360 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, FACS, ICC, IF, IHC, IHC (p), WB Flow Cytometry: B7-H1/PD-L1/CD274 Antibody [NBP1-76769] - Analysis of A-20 cells using B7-H1/PD-L1/CD274 antibody at 0.5 ug/ml. Green: Isotype control. Red : B7-H1/PD-L1/CD274 antibody. Immunohistochemistry: B7-H1/PD-L1/CD274 Antibody [NBP1-76769] - Staining of human heart tissue with antibody at 2.5 ug/mL. 0.1 mg Log in to see 7 to 9 Days
$538.13
Details
Human Mouse Un-conjugated FACS, IHC (p) 0.1 mg Log in to see 6 to 8 Days
$368.50
Details
Human Mouse FITC FACS 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Mouse Rat FITC FACS 0.1 mg Log in to see 6 to 8 Days
$434.50
Details
Human Mouse Un-conjugated CyTOF, FACS, IHC Detection of B7-H1/PD-L1 in Jurkat Human Cell Line by Flow Cytometry. B7-H1/PD-L1 in Human Colon Cancer. 100 μg Log in to see 8 to 9 Days
$285.60
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Immunohistochemistry-Paraffin: B7-H1/PD-L1/CD274 Antibody [ABIN268676] - B7-H1/PD-L1/CD274 (4ug/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. Immunohistochemistry: B7-H1/PD-L1/CD274 Antibody [ABIN268676] - Staining of Human Skeletal Muscle. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Mouse Goat Un-conjugated CyTOF, FACS, IHC, WB Detection of Mouse B7-H1/PD-L1 by Western Blot. Western blot shows lysates of RAW 264.7 mouse monocyte/macrophage cell line untreated (-) or treated (+) with 10 ug/mL LPS for 4 hours. PVDF membrane was probed with 0.5 ug/mL of Goat Anti-Mouse B7-H1/PD-L1 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. Detection of B7-H1/PD-L1 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line either treated with LPS overnight (filled histogram) or untreated (open histogram) was stained with Goat Anti-Mouse B7-H1/PD-L1 Antigen Affinity-purified Polyclonal Antibody. 100 μg Log in to see 8 to 9 Days
$388.50
Details
Human Rabbit Un-conjugated WB Anti-PD-L1 Picoband antibody,  All lanes: Anti PDL1  at 0.5ug/ml WB: HEPG2 Whole Cell Lysate at 40ug Predicted bind size: 33KD Observed bind size: 33KD Anti-PD-L1 Picoband antibody,  All lanes: Anti PDL1  at 0.5ug/ml WB: Recombinant Human PDL1 Protein 0.5ng Predicted bind size: 38KD Observed bind size: 38KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse PE FACS 50 Tests Log in to see 6 to 8 Days
$368.50
Details

CD274 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PD-L1 Antibodies

  1. Mouse (Murine) Polyclonal PD-L1 Primary Antibody for CyTOF, FACS - ABIN4899388 : Wang, Yoshida, Nakaki, Hiai, Okazaki, Honjo: Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal PD-L1 Primary Antibody for FACS, IHC (p) - ABIN1449244 : Mandavilli: Hormone in the hot seat. in Nature medicine 2006 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal PD-L1 Primary Antibody for IHC (p), ELISA - ABIN1995635 : Soliman, Khalil, Antonia: PD-L1 expression is increased in a subset of basal type breast cancer cells. in PLoS ONE 2014 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal PD-L1 Primary Antibody for IHC (p), WB - ABIN2479616 : Ishida, Agata, Shibahara, Honjo: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. in The EMBO journal 1992 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal PD-L1 Primary Antibody for IHC, ELISA - ABIN1002984 : Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal PD-L1 Primary Antibody for ELISA, FACS - ABIN4282770 : Aguilar, Shirley, Chung, Marsh, Walker, Coyle, Marx, Bekaii-Saab, Lesinski, Swanson, Sanchez, Manzanera, Aguilar-Cordova, Bloomston: Gene-mediated cytotoxic immunotherapy as adjuvant to surgery or chemoradiation for pancreatic adenocarcinoma. in Cancer immunology, immunotherapy : CII 2015 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal PD-L1 Primary Antibody for IHC, ELISA - ABIN185339 : Thompson, Gillett, Cheville, Lohse, Dong, Webster, Krejci, Lobo, Sengupta, Chen, Zincke, Blute, Strome, Leibovich, Kwon: Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal PD-L1 Primary Antibody for FACS - ABIN2479611 : Kanai, Totsuka, Uraushihara, Makita, Nakamura, Koganei, Fukushima, Akiba, Yagita, Okumura, Machida, Iwai, Azuma, Chen, Watanabe: Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)

More Antibodies against PD-L1 Interaction Partners

Mouse (Murine) CD274 Molecule (CD274) interaction partners

  1. It was concluded that down-regulated expression of miR (show MLXIP Antibodies)-143 and up-regulation of its direct target B7H1 may indicate a novel therapeutic method for radiation-induced thymic lymphoma by increased expression of miR (show MLXIP Antibodies)-143 or inhibition of B7H1.

  2. HDAC6 inhibition reduces tu (show HDAC6 Antibodies)mor growth and PD-L1 production in vivo.

  3. findings indicate that the PerC (show PPARGC1B Antibodies) B cells, including PD-L1/PD-L2 (show PDCD1LG2 Antibodies) B-1a cells, may suppress T cells responding to allostimulation, and thus may be optimal for donor lymphocyte injection

  4. PD-L1 selectively enhances T cell-mediated immune responses, driving graft-versus-host disease lethality and suggesting a context-dependent function of the PD-1 (show PDCD1 Antibodies)/PD-L1 axis

  5. Mesenteric lymph node CD11b (show ITGAM Antibodies)(-) CD103 (show ITGAE Antibodies)(+) PD-L1(High) dendritic cell subset probably takes up luminal antigens in the intestine, migrates to MLNs, and highly induces regulatory T cells through TGF-beta (show TGFB1 Antibodies) activation.

  6. These results indicate that the outcome of PD-L1-mediated signaling in CD8 (show CD8A Antibodies)+ T cells depends on the presence or absence of CD4 (show CD4 Antibodies)+ T cells, the nature of the interacting receptor expressed by CD8 (show CD8A Antibodies)+ T cells, and the tissue environment in which the signaling occurs.

  7. CD169 (show SIGLEC1 Antibodies)(+) macrophages are important contributors to the IFN-I response and thereby influence antiviral activity, CD8 (show CD8A Antibodies)(+) T-cell exhaustion and immunopathology.

  8. findings identify a previously unrecognized role of PD-L1 as an endogenous pain inhibitor and a neuromodulator.

  9. reduced cytotoxicity as a key mechanism by which tumor PD-L1 suppresses antitumor immunity and demonstrate that tumor PD-L1 is not just a marker of suppressed antitumor immunity.

  10. Apigenin inhibits IFN-gamma-induced (show SAMHD1 Antibodies) PD-L1 expression by breast cancer cells, potentially rendering BC cells that lack constitutive PD-L1 expression more susceptible to T cellmediated anti-tumor immune responses.

Human CD274 Molecule (CD274) interaction partners

  1. PD-L1 protein expression was significantly higher in smoking-associated adenocarcinoma and in EGFR (show EGFR Antibodies) mutation-negative adenocarcinoma. PD-L1 protein expression was associated with poor survival in patients with lung adenocarcinoma.

  2. Low PD-L1 expression is associated with pediatric solid tumors.

  3. Increased BAG-1 (show BAG1 Antibodies) by PD-L1 confers resistance to tyrosine kinase (show TXK Antibodies) inhibitor in non-small cell lung cancer via persistent activation of ERK (show EPHB2 Antibodies) signaling.

  4. PD-L1 expression is an important prognostic factor in patients with pancreatic ductal adenocarcinoma who underwent surgical resection.

  5. PD-L1 detection in cancer cells and immune cells varied by antibody clone.

  6. A meta-analysis indicates that circulating sPD (show HOXD13 Antibodies)-L1 changes may serve as a useful biomarker for cancer prognosis, and higher level of sPD (show HOXD13 Antibodies)-L1 may also be associated with poor outcomes in patients with cancer. Review.

  7. Expression of PD-L1 in Hodgkin Lymphoma patients is positively correlated with microvessel density.

  8. Activation of GPR81 (show GPR81 Antibodies) decreases intracellular cAMP levels and inhibits PKA activity, leading to activation of TAZ (show TAZ Antibodies) and upregulation of PD-L1. This study reveals a critical role for lactate in the immune checkpoint pathway and an unexpected function of TAZ (show TAZ Antibodies) in tumor evasion of the T-cell-mediated immune response.

  9. PD-L1 expression is not a prognostic factor in surgically resected lung adenocarcinoma patients.

  10. In gastric cancer (GC), tumour-derived GM-CSF (show CSF2 Antibodies) activated neutrophils and induced neutrophil PD-L1 expression via Janus kinase (JAK (show JAK3 Antibodies))-signal transducer and activator of transcription 3 (STAT3 (show STAT3 Antibodies)) signalling pathway. The activated PD-L1(+) neutrophils effectively suppressed normal T-cell immunity in vitro and contributed to the growth and progression of human GC in vivo.

Pig (Porcine) CD274 Molecule (CD274) interaction partners

  1. These results suggest that the soluble recombinant proteins may be used to prepare monoclonal antibodies to block the PD-1 (show PDCD1 Antibodies)/PD-L1 pathway.

  2. role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development

  3. These data suggest that overexpression of PD-L1 and PD-L2 (show PDCD1LG2 Antibodies) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.

  4. Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.

  5. A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.

Cow (Bovine) CD274 Molecule (CD274) interaction partners

  1. This study provides novel information for the understanding of signalling through PD-L1.

PD-L1 (CD274) Antigen Profile

Protein Summary

Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Gene names and symbols associated with anti-CD274 Molecule (CD274) Antibodies

  • CD274 molecule (CD274) antibody
  • CD274 molecule (LOC100357106) antibody
  • CD274 antigen (Cd274) antibody
  • CD274 molecule (Cd274) antibody
  • programmed cell death 1 ligand 2 (PDCD1LG2) antibody
  • A530045L16Rik antibody
  • B7-H antibody
  • B7H1 antibody
  • PD-L1 antibody
  • PDCD1L1 antibody
  • PDCD1LG1 antibody
  • PDL1 antibody
  • RGD1566211 antibody

Protein level used designations for anti-CD274 Molecule (CD274) Antibodies

CD274 molecule , CD274 antigen , programmed cell death 1 ligand 1 , programmed cell death ligand 1 , B7 homolog 1 , PDCD1 ligand 1 , programmed death ligand 1

GENE ID SPECIES
427224 Gallus gallus
464981 Pan troglodytes
716043 Macaca mulatta
100126721 Papio anubis
100357106 Oryctolagus cuniculus
60533 Mus musculus
29126 Homo sapiens
499342 Rattus norvegicus
100722088 Cavia porcellus
574058 Sus scrofa
484186 Canis lupus familiaris
533834 Bos taurus
427225 Gallus gallus
Selected quality suppliers for anti-PD-L1 (CD274) Antibodies
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