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Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Additionally we are shipping PD-L1 Proteins (76) and PD-L1 Kits (42) and many more products for this protein.
Showing 10 out of 339 products:
Human Monoclonal PD-L1 Primary Antibody for FACS, IHC (p) - ABIN1449244
Mandavilli: Hormone in the hot seat. in Nature medicine 2006
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Human Polyclonal PD-L1 Primary Antibody for IF, IHC (p) - ABIN500467
Chentoufi, Kritzer, Tran, Dasgupta, Lim, Yu, Afifi, Jiang, Carpenter, Osorio, Hsiang, Nesburn, Wechsler, BenMohamed: The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism. in Journal of virology 2011
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Human Polyclonal PD-L1 Primary Antibody for EIA, WB - ABIN401427
Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004
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Mouse (Murine) Monoclonal PD-L1 Primary Antibody for FACS - ABIN317020
Kanai, Totsuka, Uraushihara, Makita, Nakamura, Koganei, Fukushima, Akiba, Yagita, Okumura, Machida, Iwai, Azuma, Chen, Watanabe: Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2003
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Human Monoclonal PD-L1 Primary Antibody for FACS - ABIN2853592
del Rio, Rodriguez-Barbosa, Kremmer, Förster: CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells. in Journal of immunology (Baltimore, Md. : 1950) 2007
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Human Monoclonal PD-L1 Primary Antibody for FACS - ABIN1449174
Iwai, Okazaki, Nishimura, Kawasaki, Yagita, Honjo: Microanatomical localization of PD-1 in human tonsils. in Immunology letters 2002
Show all 2 references for ABIN1449174
Human Monoclonal PD-L1 Primary Antibody for FACS, IHC - ABIN4899390
Rojas, Krishnan: IFN-gamma generates maturation-arrested dendritic cells that induce T cell hyporesponsiveness independent of Foxp3+ T-regulatory cell generation. in Immunology letters 2010
Human Monoclonal PD-L1 Primary Antibody for FACS - ABIN4896033
Nicolazzo, Raimondi, Mancini, Caponnetto, Gradilone, Gandini, Mastromartino, Del Bene, Prete, Longo, Cortesi, Gazzaniga: Monitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab. in Scientific reports 2016
PD-1 (show PDCD1 Antibodies)/PD-L1 plays a crucial role in maintaining immune tolerance induced by UVB-iDCs, as well as in actively controlling effector T cells specific to alloantigens.
Data show that Qiyusanlong decoction (QYSL) can moderately inhibit the growth of the transplanted tumor by decreasing programmed death 1 (show PDCD1 Antibodies) and programmed death ligand 1 (PD-1 (show PDCD1 Antibodies)/PD-L1) level.
Expression of PD-L1 is correlated with the severity of periodontitis in the mouse model of experimental periodontitis.
Blockade of TGFbeta (show TGFB1 Antibodies) downregulated PD-1 (show PDCD1 Antibodies) and PD-L1 expression and precipitated graft rejection.
Loss of Cdk5 (show CDK5 Antibodies) results in persistent expression of the PD-L1 transcriptional repressors, the interferon (show IFNA Antibodies) regulatory factors IRF2 (show IRF2 Antibodies) and IRF2BP2 (show IRF2BP2 Antibodies), which likely leads to reduced PD-L1 expression on tumors.
The endogenous PD-1 (show PDCD1 Antibodies)/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.
addition to inhibiting T cells, hepatic stellate cells (HSCs) concurrently inhibit B cells via PD-L1; this direct B cell-inhibitory activity of HSCs should contribute to the mechanism by which HSCs maintain the liver's immune homeostasis
The results demonstrated that blockade of PD-1 (show PDCD1 Antibodies)/B7H1 pathway could promote mouse NK cells to kill the GL261GSCs, and the PD-1 (show PDCD1 Antibodies)-inhibited NK cells could be a feasible immune therapeutic approach against Glioblastoma multiforme.
These findings provide evidence for a novel immune escape mechanism during acute retroviral infection based on PD-L1 expression levels on virus infected target cells
These results suggest a novel and specific role for PspA (show SFTPA1 Antibodies) in modulating immune responses against S. pneumoniae by regulating PD-L1 expression.
PD-L1 IHC 22C3 pharmDx is a sensitive, precise, and robust companion diagnostic assay, which will facilitate safe and effective use for pembrolizumab in cancer patients
The interaction of programmed death-1 (PD-1 (show PDCD1 Antibodies)) with its ligand, programmed death ligand-1 (PD-L1), has been considered to play a key role in the negative regulation of immune responses. Patients with diffuse cutaneous systemic sclerosis (SSc (show CYP11A1 Antibodies)) had higher levels of soluble PD-1 (show PDCD1 Antibodies) (sPD (show HOXD13 Antibodies)-1) than those with limited cutaneous SSc (show CYP11A1 Antibodies) and healthy individuals.
identify PDL1 and MUM1 (show IRF4 Antibodies) as prognostic biomarkers for high-risk disease in primary mediastinal large B-cell lymphoma
VZV downregulates PD-L1 expression in infected brain, lung and neural cells, which, together with the noted VZV-mediated downregulation of MHC-I, might foster persistent inflammation in vessels, leading to pathological vascular remodeling during VZV vasculopathy and persistent inflammation in infected lungs.
findings demonstrate that elevated levels of PD-1 (show PDCD1 Antibodies)/PD-L1, TGF-beta (show TGFB1 Antibodies), and IL-10 (show IL10 Antibodies) in peripheral blood of cervical cancer patients may negatively regulate immune response against cervical cancer cells and contribute to the progression of cervical cancer.
PD-L1 expression is positively correlated with c-Met expression in esophageal squamous cell carcinoma
Results show that Sox2 (show SOX2 Antibodies) and PD-L1 expression are significantly higher in hepatocellular carcinoma tissues (HCC (show FAM126A Antibodies)) and that Sox2 (show SOX2 Antibodies) transactivates PD-L1 through its promoter providing a novel insight into the function and the interplay of Sox2 (show SOX2 Antibodies) and PD-L1 in HCC (show FAM126A Antibodies).
overexpressed PD-L1 was positively correlated with HPV16E7 in cervical cancer cells, which itself may have been responsible for lymphocyte dysfunction.
Data found high expression level of PD-L1 in clear cell renal cell carcinoma (show MOK Antibodies) which seems to be associated with non-inactivated VHL (show VHL Antibodies) tumors, and poor prognosis.
PD-L1 is primarily expressed by macrophages in ovarian cancer and is strongly associated with both cytolytic and regulatory TIL (show TLR1 Antibodies) subsets, resulting in a net positive association with survival.
role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development
These data suggest that overexpression of PD-L1 and PD-L2 (show PDCD1LG2 Antibodies) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.
Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.
A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.
This study provides novel information for the understanding of signalling through PD-L1.
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
, CD274 antigen
, programmed cell death 1 ligand 1
, programmed cell death ligand 1
, B7 homolog 1
, PDCD1 ligand 1
, programmed death ligand 1