CD2-Associated Protein (Cd2ap) ELISA Kits

Cd2ap encodes a scaffolding molecule that regulates the actin cytoskeleton. Additionally we are shipping CD2-Associated Protein Antibodies (43) and CD2-Associated Protein Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Cd2ap 23607 Q9Y5K6
Cd2ap 12488 Q9JLQ0
Anti-Rat Cd2ap Cd2ap 316258  
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 4.7 pg/mL 18.75-1200 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
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More ELISA Kits for CD2-Associated Protein Interaction Partners

Human CD2-Associated Protein (Cd2ap) interaction partners

  1. CD2AP expression in renal tubules may histologically associate with tissue hypoxia and reflected recovery from CsA-mediated renal injury in nephrotic syndrome patients.

  2. data thus reveal a Golgi-traversing pathway for exosomal release of the cargo protein GPRC5B (show GPRC5B ELISA Kits) in which CD2AP facilitates the entry and LMAN2 (show LMAN2 ELISA Kits) impedes the exit of the flux, respectively.

  3. Silencing Cindr in nephrocytes led to dramatic nephrocyte functional impairment and shortened life span, as well as collapse of nephrocyte lacunar channels and effacement of nephrocyte slit diaphragms. These phenotypes could be rescued by expression of a wild-type human CD2AP gene, but not a mutant allele derived from a patient with CD2AP-associated NS.

  4. Study found a novel association of CD2AP with plasma homocysteine in participants with African ancestry and found a new variant in the candidate gene CBS (show CBS ELISA Kits) associated with homocysteine

  5. CD2AP rs9349407 polymorphism contributes to Alzheimer's disease susceptibility.

  6. discovered novel interaction candidates for CD2AP and characterized subtle yet significant differences in the recognition preferences of its three SH3 domains for c-CBL (show CBL ELISA Kits), ALIX (show PDCD6IP ELISA Kits), and RIN3 (show RIN3 ELISA Kits)

  7. we present the first demonstration that the purified SH3 domains of the CD2AP/Cin85 (show SH3KBP1 ELISA Kits) protein family are able to directly bind the p53 (show TP53 ELISA Kits) protein, and to discriminate between the two polymorphic variants P72R

  8. CD2-Associated Protein affects Abeta (show APP ELISA Kits) levels and Abeta42/Abeta40 ratio in vitro

  9. CD2AP gene variants may contribute to susceptibility to end-stage renal disease in patients with type 1 diabetes.

  10. FSGS3/CD2AP has a role of barbed-end capping in junctional actin dynamics.

Mouse (Murine) CD2-Associated Protein (Cd2ap) interaction partners

  1. Bin1 (show BIN1 ELISA Kits) and CD2AP keep APP (show APP ELISA Kits) and BACE1 (show BACE ELISA Kits) apart in early endosomes by distinct mechanisms in axon and dendrites. Individuals carrying variants of either factor would slowly accumulate Abeta (show APP ELISA Kits) in neurons increasing the risk for late-onset AD.

  2. CD2AP forms a complex with GGA2 (show GGA2 ELISA Kits), a clathrin adaptor, which sorts Glut4 (show SLC2A4 ELISA Kits) to GSVs, suggesting a role for CD2AP in this process.

  3. CD2AP is the first signaling molecule associated with adult sensory axonal collateral sprouting

  4. CD2AP has role in mediating blood-brain barrier integrity and cerebrovascular roles of CD2AP could contribute to its effects on Alzheimer's disease risk.

  5. CD2-Associated Protein affects Abeta (show APP ELISA Kits) levels and Abeta42/Abeta40 ratio in vitro

  6. only the SH3 domains of CD2AP are necessary to enhance the E3 ligase activity of Cbl-3 (show CBLC ELISA Kits)/c toward Ret51 (show RET ELISA Kits)

  7. CD2AP is not involved in the regulation of type I IFNs in plasmacytoid dendritic cells. Its major function is on the actin cytoskeleton, affecting migration to local lymph nodes under conditions of inflammation.

  8. CD2AP deficiency results in the excretion of intact albumin (show ALB ELISA Kits) in knockout mice.

  9. the formation of lamellipodia is mediated by a complex of cortactin (show CTTN ELISA Kits), CD2AP, and actin capping protein (show TMOD4 ELISA Kits)

  10. These data descrived the importance of concomitant decreases in podocin, CD2AP and tensin2 during septic acute renal failure-associated proteinuria.

CD2-Associated Protein (Cd2ap) Antigen Profile

Antigen Summary

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Gene names and symbols associated with Cd2ap

  • CD2-associated protein (cd2ap) antibody
  • CD2-associated protein (CD2AP) antibody
  • CD2-associated protein (Cd2ap) antibody
  • AL024079 antibody
  • C78928 antibody
  • cd2apl antibody
  • CMS antibody
  • DKFZp469E061 antibody
  • fj51c01 antibody
  • im:7153970 antibody
  • METS-1 antibody
  • Mets1 antibody
  • si:ch211-207n9.1 antibody
  • wu:fj51c01 antibody
  • zgc:103705 antibody

Protein level used designations for Cd2ap

CD2-associated protein , Cas ligand with multiple Src homology 3 (SH3) domains , adapter protein CMS , cas ligand with multiple SH3 domains , hypothetical protein , SH3 domain-containing adapter protein , SH3 domain-containing adaptor protein METS-1 , mesenchyme to epithelium transition protein, SH3 domains , mesenchyme-to-epithelium transition protein with SH3 domains 1

445851 Xenopus laevis
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494040 Danio rerio
705221 Macaca mulatta
100014892 Monodelphis domestica
100158527 Xenopus (Silurana) tropicalis
100172673 Pongo abelii
100341696 Oryctolagus cuniculus
100386627 Callithrix jacchus
100466982 Ailuropoda melanoleuca
100554210 Anolis carolinensis
100600076 Nomascus leucogenys
23607 Homo sapiens
771715 Gallus gallus
474928 Canis lupus familiaris
533188 Bos taurus
12488 Mus musculus
316258 Rattus norvegicus
100731393 Cavia porcellus
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