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CD300A encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. Additionally we are shipping CD300a Molecule Proteins (18) and CD300a Molecule Kits (2) and many more products for this protein.
Showing 10 out of 71 products:
Mouse (Murine) Monoclonal CD300A Primary Antibody for FACS, IF - ABIN2665985
Borrego: The CD300 molecules: an emerging family of regulators of the immune system. in Blood 2013
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Human Monoclonal CD300A Primary Antibody for FACS - ABIN238466
Cantoni, Bottino, Augugliaro, Morelli, Marcenaro, Castriconi, Vitale, Pende, Sivori, Millo, Biassoni, Moretta, Moretta: Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells. in European journal of immunology 1999
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Human Monoclonal CD300A Primary Antibody for FACS, WB - ABIN192409
Alvarez, Tang, Coligan, Borrego: The CD300a (IRp60) inhibitory receptor is rapidly up-regulated on human neutrophils in response to inflammatory stimuli and modulates CD32a (FcgammaRIIa) mediated signaling. in Molecular immunology 2007
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Human Monoclonal CD300A Primary Antibody for FACS, WB - ABIN238465
Bachelet, Munitz, Levi-Schaffer: Abrogation of allergic reactions by a bispecific antibody fragment linking IgE to CD300a. in The Journal of allergy and clinical immunology 2006
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Human Monoclonal CD300A Primary Antibody for FACS - ABIN2479883
Vizkelety, Rényi-Vámos, Szöke: Surgical treatment of the hip in cerebral palsy. in Acta chirurgica Hungarica 1993
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Mouse (Murine) Monoclonal CD300A Primary Antibody for FACS - ABIN1449208
Steinman, Cohn: Pillars Article: Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med.1973. 137: 1142-1162. in Journal of immunology (Baltimore, Md. : 1950) 2006
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Human Polyclonal CD300A Primary Antibody for ELISA - ABIN1999719
Bachelet, Munitz, Moretta, Moretta, Levi-Schaffer: The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells. in Journal of immunology (Baltimore, Md. : 1950) 2005
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Epithelial apoptotic cells negatively regulated commensal-mediated signaling in dendritic cells via CD300a for Treg cell proliferation.
Data show that peroxisome proliferator activator receptor delta (PPARdelta/beta (show PPARD Antibodies)) directly regulates CD300a protein in macrophages.
These results suggest that CD300a is involved in aluminium-induced Th2 skewing.
study demonstrates a new tumor immune evasion mechanism that is mediated through the interaction between phosphatidylserine and CD300a and we suggest that CD300c (show CD300C Antibodies), similarly to CD300a, also interacts with phosphatidylserine.
CD300a-deficient mice showed increased neutrophil recruitment and improved bacterial clearance in the peritoneal cavity.
These results indicated that CD300a is a new phosphatidylserine receptor (show JMJD6 Antibodies).
Molecular cloning and characterization of leukocyte mono-immunoglobulin-like receptor1 and 2 derived from mast cells [LMIR1] [LMIR2]
in a murine model of allergic peritonitis, neutralization of the murine homolog of IRp60, LMIR1, led to a significantly augmented release (show RNASE2 Antibodies) of inflammatory mediators and eosinophilic infiltration.
Results provide an insight into the novel set of paired receptors CD300a and CD300c (show CD300C Antibodies) that are distinctively expressed on CD56 (show NCAM1 Antibodies)(bright) natural killers (NK) cells with varied effector functions and show there differential binding to their ligands phosphatidylethanolamine and phosphatidylserine (PS) resulting in their differential ability to affect CD56 (show NCAM1 Antibodies)(bright) NK cell functions.
High CD300A expression is associated with diffuse large B-cell lymphoma.
US3 protein kinase (show CDK7 Antibodies) of pseudorabies virus triggers the binding of the inhibitory natural killer cell receptor CD300a to the surface of the infected cell, and protects of virus infected cells against natural killer cell-mediated lysis.
Overall, these data indicate that CD300a is a novel Dengue virus binding receptor that recognizes phosphatidylethanolamine and phosphatidylserine present on virions and enhance infection.
CD300a induction by the hypoxic environment represents a mechanism of regulation of monocyte/macrophage pro-inflammatory responses at pathologic sites
interaction with phosphatidylserines inhibits IgE/FcepsilonRI (show FCER1G Antibodies)-dependent anaphylactic basophil degranulation
The inhibitory receptor CD300a is regulator of monocytes transendothelial migration.
SHP-1 (show PTPN6 Antibodies), but not SHP-2 (show PTPN11 Antibodies) or the src homology 2 domain containing inositol 5' phosphatase (show INPP5D Antibodies) SHIP, was utilized by CD300a for its inhibitory activity. These studies provide new insights into the function of CD300a in tuning T and B cell responses.
CD300a is expressed on human peripheral blood basophils and rapidly up-regulated upon cross-linking of IgE/Fc-epsilon-RI and suppresses anaphylactic degranulation.
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene.
, CD300 antigen-like family member
, CMRF35-like molecule 8
, CD300 antigen-like family member A
, leukocyte mono-Ig-like receptor 1
, mast cell-derived paired immunoglobulin-like receptor 1
, myeloid-associated immunoglobulin-like receptor 1
, polymeric immunoglobulin receptor 4
, CD300a antigen
, CMRF35H leukocyte immunoglobulin-like receptor
, NK inhibitory receptor
, immunoglobulin superfamily member 12
, inhibitory receptor protein 60
, leukocyte membrane antigen
, immune inhibitory receptor CD300A