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CD33 Molecule Proteins (CD33)

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Additionally we are shipping CD33 Antibodies (618) and CD33 Kits (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD33 12489 Q63994
CD33 945 P20138
Rat CD33 CD33 690492  
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Top CD33 Proteins at antibodies-online.com

Showing 10 out of 29 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$319.00
Details
HOST_HEK-293 Human Fc Tag   25 μg Log in to see 10 to 12 Days
$201.11
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_HEK-293 Human His tag 50 μg Log in to see 2 to 3 Days
$651.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Cynomolgus His tag 100 μg Log in to see 16 Days
$382.80
Details

CD33 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , ,
, , ,
Human , , , , , , ,
, , , , ,

Top referenced CD33 Proteins

  1. Human CD33 Protein expressed in HEK-293 - ABIN2666955 : Angata: Associations of genetic polymorphisms of Siglecs with human diseases. in Glycobiology 2014 (PubMed)
    Show all 6 references for ABIN2666955

  2. Human CD33 Protein expressed in HEK-293 Cells - ABIN2180756 : Robillard, Cavé, Méchinaud, Guidal, Garnache-Ottou, Rohrlich, Avet-Loiseau, Garand: Four-color flow cytometry bypasses limitations of IG/TCR polymerase chain reaction for minimal residual disease detection in certain subsets of children with acute lymphoblastic leukemia. in Haematologica 2005 (PubMed)
    Show all 2 references for ABIN2180756

More Proteins for CD33 Molecule (CD33) Interaction Partners

Mouse (Murine) CD33 Molecule (CD33) interaction partners

  1. Lectin galactoside-binding soluble 3 binding protein (LGALS3BP (show LGALS3BP Proteins)) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs.

  2. CD33-related Siglec-E recognizes the intact neuron and has neuroprotective function by preventing phagocytosis.

  3. SOCS3 (show SOCS3 Proteins) inhibited the CD33-induced block on cytokine-induced proliferation. SOCS3 (show SOCS3 Proteins) and its target protein CD33 are degraded concomitantly concomitantly.

Human CD33 Molecule (CD33) interaction partners

  1. There is substantial evidence that rs3865444 (CD33) function is related to AD pathways and pathology, but our data does not support an interaction with rs670139 (MS4A4E) that impacts AD risk.

  2. this study investigated the contribution of the immunoregulatory receptor CD33 to a uniquely human postreproductive disease, Alzheimer's dementia.

  3. the CD33 rs3865444 polymorphism is associated with Alzheimer's disease susceptibility in Chinese, European, and North American populations.

  4. CD33 and MS4A cluster variants are associated with LOAD susceptibility in East Asian populations.

  5. Among those with one or more APOE (show APOE Proteins) epsilon4 alleles, having one or more copies of the CD33 C (risk) allele may further increase the risk of cognitive decline

  6. decreased TREM2 (show TREM2 Proteins) expression with CD33 suppression and elevated cortical TREM2 (show TREM2 Proteins) mRNA expression with amyloid pathology

  7. we propose a model wherein a modest effect on RNA splicing is sufficient to mediate the CD33 association with AD risk and suggest the potential for an anti-CD33 antibody as an AD-relevant pharmacologic agent.

  8. Studies indicate that anti-CD19 (show CD19 Proteins) and anti-CD33 bispecific antibodies showed anticancer activity.

  9. Its single-nucleotide polymorphism rs3865444 in the CD33 gene as being associated with the reduced risk of developing Alzheimer's disease.

  10. 87.8% of AMLs express CD33. Additionally, 9.4% of AMLs express CD123 (show IL3RA Proteins) without concomitant CD33 expression.

CD33 Protein Profile

Protein Summary

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Gene names and symbols associated with CD33 Molecule Proteins (CD33)

  • CD33 molecule (CD33)
  • CD33 antigen (Cd33)
  • CD33 molecule (Cd33)
  • gp67 protein
  • p67 protein
  • SIGLEC-3 protein
  • SIGLEC3 protein

Protein level used designations for CD33 Molecule Proteins (CD33)

CD33 antigen (gp67) , myeloid cell surface antigen CD33 , sialic acid-binding Ig-like lectin 3 , gp67 , sialic acid binding Ig-like lectin 3

GENE ID SPECIES
456242 Pan troglodytes
12489 Mus musculus
945 Homo sapiens
690492 Rattus norvegicus
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