anti-CD33 Molecule (CD33) Antibodies

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Additionally we are shipping CD33 Kits (36) and CD33 Proteins (32) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD33 12489 Q63994
CD33 945 P20138
CD33 690492  
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Top anti-CD33 Antibodies at antibodies-online.com

Showing 10 out of 639 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CD33 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse PE FACS Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD33:RPE 100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Mouse Un-conjugated FACS, IHC (fro), IP, WB Staining of human peripheral blood monocytes with Mouse anti Human CD33 using antibody ABIN118637 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Mouse FITC FACS Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD33:FITC 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Human Mouse APC FACS Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD33:APC (ABIN118633) 100 Tests Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Rabbit Anti CD33/Siglec-3 Polyclonal Antibody, Unconjugated (ABIN676958) at 1:200 followed by conjugation to the secondary antibody and DAB staining Human U937 cells probed with CD33 Polyclonal Antibody, Unconjugated  at 0.2ug for 30 minutes followed by incubation with a PE Conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). 100 μL Log in to see 3 to 7 Days
$307.45
Details
Mouse Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Rabbit Anti CD33/Siglec-3 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse intestine labeled with Rabbit Anti CD33/Siglec-3 Polyclonal Antibody, Unconjugated (ABIN687607) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$430.10
Details
Human Mouse Un-conjugated FACS, IP, WB   25 μg Log in to see 6 to 8 Days
$176.00
Details

CD33 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CD33 Antibodies

  1. Human Monoclonal CD33 Primary Antibody for FACS, Func - ABIN1302476 : Schenk, Bouchon, Birrer, Colonna, Mueller: Macrophages expressing triggering receptor expressed on myeloid cells-1 are underrepresented in the human intestine. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 8 Pubmed References

  2. Human Monoclonal CD33 Primary Antibody for FACS, Func - ABIN1302947 : Garnache-Ottou, Chaperot, Biichle, Ferrand, Remy-Martin, Deconinck, de Tailly, Bulabois, Poulet, Kuhlein, Jacob, Salaun, Arock, Drenou, Schillinger, Seilles, Tiberghien, Bensa, Plumas, Saas: Expression of the myeloid-associated marker CD33 is not an exclusive factor for leukemic plasmacytoid dendritic cells. in Blood 2005 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal CD33 Primary Antibody for FACS, Func - ABIN1302526 : Leone, Rutella, Bonanno, Abbate, Rebuzzi, Giovannini, Lombardi, Galiuto, Liuzzo, Andreotti, Lanza, Contemi, Leone, Crea: Mobilization of bone marrow-derived stem cells after myocardial infarction and left ventricular function. in European heart journal 2005 (PubMed)
    Show all 8 Pubmed References

  4. Human Monoclonal CD33 Primary Antibody for FACS, Func - ABIN1303156 : Vitale, Romagnani, Puccetti, Olive, Costello, Chiossone, Pitto, Bacigalupo, Moretta, Mingari: Surface expression and function of p75/AIRM-1 or CD33 in acute myeloid leukemias: engagement of CD33 induces apoptosis of leukemic cells. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 8 Pubmed References

  5. Human Monoclonal CD33 Primary Antibody for FACS, Func - ABIN780369 : Shin, Choi, Kim, Chung, Chung, Park, Jung, Kim, Park, Kim, Park, Min, Kim, Park: Expression of leukemia-associated antigen, JL1, in bone marrow and thymus. in The American journal of pathology 2001 (PubMed)
    Show all 8 Pubmed References

  6. Human Monoclonal CD33 Primary Antibody for FACS, Func - ABIN775711 : Bradstock, Kirk, Grimsley, Kabral, Hughes: Unusual immunophenotypes in acute leukaemias: incidence and clinical correlations. in British journal of haematology 1989 (PubMed)
    Show all 8 Pubmed References

  7. Human Monoclonal CD33 Primary Antibody for FACS - ABIN2689194 : Nakamura, Noma, Kidokoro, Kobayashi, Takei, Kurashima, Mukaiyama, Kato: Expression of CD33 antigen on normal human activated T lymphocytes. in Blood 1994 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal CD33 Primary Antibody for FACS - ABIN2689195 : Favaloro, Moraitis, Koutts, Exner, Bradstock: Endothelial cells and normal circulating haemopoietic cells share a number of surface antigens. in Thrombosis and haemostasis 1989 (PubMed)
    Show all 3 Pubmed References

  9. Human Monoclonal CD33 Primary Antibody for FACS, IHC - ABIN1724813 : Schubert, Kellner, Stein, Kügler, Schwenkert, Saul, Mentz, Singer, Stockmeyer, Hillen, Mackensen, Fey: A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting. in mAbs 2011 (PubMed)
    Show all 2 Pubmed References

  10. Human Monoclonal CD33 Primary Antibody for FACS, IHC - ABIN1724812 : Deng, Liu, Wang, Tang, Ren, Xu, Ma, Wang, Zhuang, Wang, Chen: The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease. in Human genetics 2012 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CD33 Interaction Partners

Mouse (Murine) CD33 Molecule (CD33) interaction partners

  1. Lectin galactoside-binding soluble 3 binding protein (LGALS3BP (show LGALS3BP Antibodies)) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs.

  2. CD33-related Siglec-E recognizes the intact neuron and has neuroprotective function by preventing phagocytosis.

  3. SOCS3 (show SOCS3 Antibodies) inhibited the CD33-induced block on cytokine-induced proliferation. SOCS3 (show SOCS3 Antibodies) and its target protein CD33 are degraded concomitantly concomitantly.

Human CD33 Molecule (CD33) interaction partners

  1. Data suggest that two SNPs in CD33 (rs3865444A, rs12459419T) that are protective of Alzheimer disease result in splice variants (CD33M, CD33m); CD33M localizes predominantly at cell surface in macrophage cell line; CD33m is primary intracellular form in neutrophils and a microglia cell line; intracellular CD33m accumulates in peroxisomes; activation of macrophages/neutrophils does not mobilize CD33m to cell surface.

  2. In cutaneous diffuse large b-cell lymphoma, a considerable proportion of CD33(+) myeloid-derived suppressor cells (MDSCs) with PD-L1 (show CD274 Antibodies) coexpression was admixed. Tumor cells expressed CD33 to variable degrees (2% to 60%). We propose that PD-L1 (show CD274 Antibodies)(+) tumor cells and PD-L1 (show CD274 Antibodies)(+) MDSCs shield the tumor against PD-1 (show PDCD1 Antibodies)(+) tumor-infiltrating lymphocytes, consequently leading to inhibition and diminution of tumor-infiltrating lymphocytes.

  3. CD33-expressing microglia play a central role in the development of leukoencephalopathy in Nasu-Hakola disease brains

  4. There is substantial evidence that rs3865444 (CD33) function is related to AD pathways and pathology, but our data does not support an interaction with rs670139 (MS4A4E) that impacts AD risk.

  5. this study investigated the contribution of the immunoregulatory receptor CD33 to a uniquely human postreproductive disease, Alzheimer's dementia.

  6. the CD33 rs3865444 polymorphism is associated with Alzheimer's disease susceptibility in Chinese, European, and North American populations.

  7. CD33 and MS4A cluster variants are associated with LOAD susceptibility in East Asian populations.

  8. Among those with one or more APOE (show APOE Antibodies) epsilon4 alleles, having one or more copies of the CD33 C (risk) allele may further increase the risk of cognitive decline

  9. decreased TREM2 (show TREM2 Antibodies) expression with CD33 suppression and elevated cortical TREM2 (show TREM2 Antibodies) mRNA expression with amyloid pathology

  10. we propose a model wherein a modest effect on RNA splicing is sufficient to mediate the CD33 association with AD risk and suggest the potential for an anti-CD33 antibody as an AD-relevant pharmacologic agent.

CD33 Antigen Profile

Protein Summary

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Gene names and symbols associated with anti-CD33 Molecule (CD33) Antibodies

  • CD33 molecule (CD33) antibody
  • CD33 antigen (Cd33) antibody
  • CD33 molecule (Cd33) antibody
  • gp67 antibody
  • p67 antibody
  • SIGLEC-3 antibody
  • SIGLEC3 antibody

Protein level used designations for anti-CD33 Molecule (CD33) Antibodies

CD33 antigen (gp67) , myeloid cell surface antigen CD33 , sialic acid-binding Ig-like lectin 3 , gp67 , sialic acid binding Ig-like lectin 3

GENE ID SPECIES
456242 Pan troglodytes
12489 Mus musculus
945 Homo sapiens
690492 Rattus norvegicus
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