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The protein encoded by CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. Additionally we are shipping CD44 Kits (35) and CD44 Proteins (32) and many more products for this protein.
Showing 10 out of 1454 products:
Mouse (Murine) Monoclonal CD44 Primary Antibody for FACS - ABIN114211
Miyake, Medina, Hayashi, Ono, Hamaoka, Kincade: Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures. in The Journal of experimental medicine 1990
Show all 5 references for ABIN114211
Rat (Rattus) Monoclonal CD44 Primary Antibody for FACS, IHC (fro) - ABIN114366
Arch, Wirth, Hofmann, Ponta, Matzku, Herrlich, Zöller: Participation in normal immune responses of a metastasis-inducing splice variant of CD44. in Science (New York, N.Y.) 1992
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Human Monoclonal CD44 Primary Antibody for FACS, IHC (fro) - ABIN118684
Neumayer, Rosen, Reiner, Sebesta, Schmid, Tüchler, Schiessel: CD44 expression in benign and malignant colorectal polyps. in Diseases of the colon and rectum 1999
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Rat (Rattus) Monoclonal CD44 Primary Antibody for FACS, IHC (fro) - ABIN114362
Paterson, Jefferies, Green, Brandon, Corthesy, Puklavec, Williams: Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. in Molecular immunology 1988
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Mouse (Murine) Monoclonal CD44 Primary Antibody for FACS - ABIN114208
Miyake, Underhill, Lesley, Kincade: Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition. in The Journal of experimental medicine 1990
Show all 4 references for ABIN114208
Mouse (Murine) Monoclonal CD44 Primary Antibody for FACS, IHC (fro) - ABIN114206
Picker, De los Toyos, Telen, Haynes, Butcher: Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors. in Journal of immunology (Baltimore, Md. : 1950) 1989
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Human Monoclonal CD44 Primary Antibody for FACS, IHC (fro) - ABIN118667
Yu, Toole, Stamenkovic: Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function. in The Journal of experimental medicine 1998
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Human Monoclonal CD44 Primary Antibody for EIA, IHC (p) - ABIN263995
Sneath, Mangham: The normal structure and function of CD44 and its role in neoplasia. in Molecular pathology : MP 1999
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These studies demonstrate that both endometrial cell and peritoneal mesothelial cell CD44 play a role in the development of early endometriotic lesion.
Targeting CD44 expressing colon cancer cells with anti-CD44 monoclonal antibody improves cellular uptake and antitumor efficacy of liposomal doxorubicin.
MGK as hydrophobic moieties and oHA as the target of CD44 receptor.
CD44, NOD2 (show NOD2 Antibodies), and Fas (show FAS Antibodies) have distinct functions in regulating changes in trabecular and cortical bone indices during unloading.
The absence of CD44 in neonatal bone marrow has no impact on the size of the long-term reconstituting hematopoietic stem cell pool, but results in an enhanced long-term engraftment potential of hematopoietic stem cells.
CD44 deficiency can reduce osteoclast activity and counteract cortical bone loss in the hindlimb of unloaded mice.
Genetic deficiency of CD44 augments activation, apoptosis and pro-thrombotic potential of platelets.
The high targeting ability of HA-MFNPs was observed at MKN-45 cells (gastric cancer cell line) which high-expressing CD44 in contrast with MKN-28 cells which low-expressing CD44.
the aggravation of pulmonary inflammation upon combined exposure to allergen and an environmental pollutant is CD44-dependent.
CD44 promotes chemoresistance in T-ALL by increased drug efflux.
Increased CD44s protein and posttranslational modification of CD44 with polylactosamine on macrophages from stage III could be involved in the cleaning up apoptotic granulosa cells
CD44 has a key role in oocyte maturation but not in cumulus expansion.
This study demonstrates that the CD14 (show CD14 Antibodies)-negative isolation yields an enhanced cell population SFB (show CEBPB Antibodies) that is more potent than MSCP (show SLC25A37 Antibodies) as a cell source for cartilage tissue engineering.
CD44 is expressed in the cumulus-oocyte complexes during cumulus expansion. The interaction between hyaluronan and CD44 is closely related to gap junctional communication of the cumulus-oocyte complexes during meiotic resumption.
CD44 isoforms expression in invasive micropapillary carcinoma of the breast
Real-time PCR analysis showed that the treated A549 cells highly over expressed TNF-alpha (show TNF Antibodies), which was associated with a significant reduction of CD44 gene expression levels
There was no significant difference in E-cadherin (show CDH1 Antibodies) and CD44v6 expression among the partial, complete, and invasive hydatidiform moles patient groups.
The ALDH1 (show ALDH1A1 Antibodies) activity and sphere forming ability of CD44(high) /ALDH1 (show ALDH1A1 Antibodies)(high) cells was significantly inhibited by GSK3beta (show GSK3b Antibodies) knockdown. On the other hand, CD44(high) /ALDH1 (show ALDH1A1 Antibodies)(low) cells exhibited high epidermal growth factor receptor (EGFR (show EGFR Antibodies)) expression and increased cell growth.
Analysis of KRAS mutation combined with immunohistochemical expression of CD44 and CD166 (show ALCAM Antibodies) identified subgroups of patients with colon adenocarcinoma at higher risk of lymph node involvement by the tumor and development of liver and lung metastasis.
Study shows that CD44 is an important regulator of glucose metabolism in small cell neuroendocrine carcinoma.
the authors investigated the ability of two hyaluronan-based nanoparticles targeting CD44 receptors to home in on lung cancer cells in an in-vivo orthotropic model. The preferential uptake of smaller sized nanoparticles via intravenous route has further enhanced the existing knowledge of future drug designs.
Although LCN2 (show LCN2 Antibodies) increased intracellular iron concentrations, LCN2 (show LCN2 Antibodies)-induced GSH may catalyze and override oxidative stress via CD44 and xCT (show SLC7A11 Antibodies), and subsequently enhance the survival of clear cell carcinoma tumor cells in oxidative stress-rich environment.
loss of the CD44 expression plays role in lymphovascular permeation and metastasis and it can be hypothesized that its reexpression at metastatic site may play a role in homing of tumor cells
CD44 and CD133 might participate in early-stage endometrial cancer carcinogenesis
CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (show HYAL2 Antibodies).
release of the CD44 intracellular domain into the cytoplasm of cells such as chondrocytes exerts a competitive or dominant-negative effect on the function of full-length CD44.
CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro
determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (show IL2RA Antibodies), CD44, and CD62L (show SELL Antibodies) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.
detection of CD44 in the bovine oviductal epithelium
Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM (show HMMR Antibodies)-mediated signalling pathways involving Cdc2 (show CDK1 Antibodies) and gamma-adducin (show ADD3 Antibodies).
The novel finding that TSP-1 (show THBS1 Antibodies)-induced migration is dependent on the CD44 receptor links 2 pathways thought to be disparate (ie, TSP-1 (show THBS1 Antibodies) and HyA (show KDM5D Antibodies)).
An important role for the Hyaluronan-CD44 signaling pathway in reproductive function and inflammation.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
, GP90 lymphocyte homing/adhesion receptor
, extracellular matrix receptor III
, hermes antigen
, hyaluronate receptor
, lymphocyte antigen 24
, phagocytic glycoprotein 1
, phagocytic glycoprotein I
, CD44 antigen
, Cell surface glycoprotein CD44 (hyaluronate binding protein)
, Hermes antigen
, cell surface glycoprotein CD44
, chondroitin sulfate proteoglycan 8
, hematopoietic cell E- and L-selectin ligand
, heparan sulfate proteoglycan
, homing function and Indian blood group system
, extracellular matrix receptor-III
, CD44-like protein
, lymphocyte surface antigen precursor CD44
, syndecan 4 (amphiglycan, ryudocan)