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CD46 Proteins

(CD46)
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010].
CD46 Protein (CD46) (AA 35-343) (His tag) CD46 Protein (CD46) (AA 35-343) (His tag) CD46 Protein (CD46) (AA 35-343) (His tag) (ABIN7274180)

CD46 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

CD46 Protein (CD46) (AA 35-329) (His tag) CD46 Protein (CD46) (AA 35-329) (His tag) CD46 Protein (CD46) (AA 35-329) (His tag) (ABIN7274175)

CD46 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

CD46 Protein (CD46) (AA 45-344) (His tag) CD46 Protein (CD46) (AA 45-344) (His tag) CD46 Protein (CD46) (AA 45-344) (His tag) (ABIN7274176)

CD46 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

CD46 Proteins by Grade

Find CD46 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CD46 Proteins by Origin

Find CD46 Proteins for a variety of species such as anti-Human CD46, anti-Mouse CD46, anti-Rat CD46. The species listed below are among those available. Click on a link to go to the corresponding products.

CD46 Proteins by Source

Here you will find CD46 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CD46 Proteins by Protein Type

Here you can find CD46 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CD46 Proteins by Application

Find CD46 Proteins validated for a specific application such as ELISA, SDS, WB, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CD46 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274180
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274175
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274176
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122209
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348658
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348656
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093688
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132063
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3112950
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132064
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7519788
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN1096326
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana benthamiana)
Validations
Cat. No. ABIN7508392
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393649
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7404554
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD46 Proteins

Baker, Greenshields-Watson, Coughlan, Davies, Uusi-Kerttula, Cole, Rizkallah, Parker: "Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions." in: Nature communications, Vol. 10, Issue 1, pp. 741, (2019) (PubMed).

Stein, Gardner, Hernandez, Kraus, Duty, Ubarretxena-Belandia, Moran, Tortorella: "CD46 facilitates entry and dissemination of human cytomegalovirus." in: Nature communications, Vol. 10, Issue 1, pp. 2699, (2019) (PubMed).

Douradinha, McBurney, Soares de Melo, Smith, Krishna, Barratt-Boyes, Evans, Nascimento, Marques: "C1q binding to dengue virus decreases levels of infection and inflammatory molecules transcription in THP-1 cells." in: Virus research, Vol. 179, pp. 231-4, (2014) (PubMed).

Miyaji, Paul, Shahrizaila, Umapathi, Yuki: "Complement regulatory proteins (CD46, 55 and 59) expressed on Schwann cells: immune targets in demyelinating neuropathies?" in: Journal of neuroimmunology, Vol. 276, Issue 1-2, pp. 172-4, (2014) (PubMed).

Aliases for CD46 Proteins

CD46 molecule (CD46) Proteins
CD46 antigen, complement regulatory protein (Cd46) Proteins
CD46 molecule (Cd46) Proteins
CD46 molecule, complement regulatory protein (CD46) Proteins
membrane cofactor protein-like (LOC100341359) Proteins
membrane cofactor protein-like (LOC103789310) Proteins
AHUS2 Proteins
CD46 Proteins
MCP Proteins
Mcp Proteins
MIC10 Proteins
TLX Proteins
TRA2.10 Proteins
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