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CD47 encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. Additionally we are shipping CD47 Proteins (28) and CD47 Kits (7) and many more products for this protein.
Showing 10 out of 270 products:
Mouse (Murine) Monoclonal CD47 Primary Antibody for FACS - ABIN2661096
Gao, Lindberg, Finn, Blystone, Brown, Frazier: Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin. in The Journal of biological chemistry 1996
Show all 6 references for ABIN2661096
Human Monoclonal CD47 Primary Antibody for FACS, IP - ABIN2661095
Lindberg, Lublin, Telen, Veile, Miller, Donis-Keller, Brown: Rh-related antigen CD47 is the signal-transducer integrin-associated protein. in The Journal of biological chemistry 1994
Show all 4 references for ABIN2661095
Human Polyclonal CD47 Primary Antibody for FACS, IHC - ABIN4899369
Baccelli, Schneeweiss, Riethdorf, Stenzinger, Schillert, Vogel, Klein, Saini, Bäuerle, Wallwiener, Holland-Letz, Höfner, Sprick, Scharpff, Marmé, Sinn, Pantel, Weichert, Trumpp: Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay. in Nature biotechnology 2013
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Human Monoclonal CD47 Primary Antibody for FACS - ABIN2144616
Christensson: Fathers can effectively achieve heat conservation in healthy newborn infants. in Acta paediatrica (Oslo, Norway : 1992) 1997
Human Polyclonal CD47 Primary Antibody for ELISA, WB - ABIN4294355
Azcutia, Stefanidakis, Tsuboi, Mayadas, Croce, Fukuda, Aikawa, Newton, Luscinskas: Endothelial CD47 promotes vascular endothelial-cadherin tyrosine phosphorylation and participates in T cell recruitment at sites of inflammation in vivo. in Journal of immunology (Baltimore, Md. : 1950) 2012
Human Polyclonal CD47 Primary Antibody for FACS, IF (p) - ABIN739530
Miedel, Dishowitz, Myers, Dopkin, Yu, Miclau, Marcucio, Ahn, Hankenson: Disruption of thrombospondin-2 accelerates ischemic fracture healing. in Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2013
Human Monoclonal CD47 Primary Antibody for FACS - ABIN4896002
Albert, Veréb, Csomós, Moe, Johnsen, Olstad, Nicolaissen, Rajnavölgyi, Fésüs, Berta, Petrovski: Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium. in PLoS ONE 2012
Rat (Rattus) Monoclonal CD47 Primary Antibody for FACS, IP - ABIN119763
Vernon-Wilson, Kee, Willis, Barclay, Simmons, Brown: CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPalpha 1. in European journal of immunology 2000
atherogenesis is associated with upregulation of CD47, a key anti-phagocytic molecule that is known to render malignant cells resistant to programmed cell removal, or 'efferocytosis'
Erythrocyte CD47 has a key role in hematoma clearance after intracerebral hemorrhage.
These data indicate that CD47 plays protective roles against disseminated candidiasis and alters pro-inflammatory and immunosuppressive pathways known to regulate innate and T cell immunity.
CD47 deficiency ameliorates lupus nephritis in Fas(lpr (show FAS Antibodies)) mice via suppression of IgG autoantibody production.
the cell adhesion molecule (show MCAM Antibodies) CD47 participates in multiple phases of granule cell development, including proliferation, migration, and neurite differentiation
CD47 mediates signaling from the extracellular matrix that coordinately regulates basal metabolism and cytoprotective responses to radiation injury
Taken together, these data revealed a novel role for CD47 in the development of obesity and its related metabolic complications.
NF KB mediated CD47 up regulation promotes sorafenib resistance treating hepatocellular carcinoma.
Loss of cell surface CD47 clustering formation and binding avidity to SIRPalpha facilitate apoptotic cell clearance by macrophages.
findings prove that the TSP-1 (show GZMA Antibodies)/CD47/SIRP (show SIRPA Antibodies)-alpha signal axis is important to the evolution of tumor cells in the microenvironment of immunotherapy and identify thrombospondin-1 (show THBS1 Antibodies) as a key signal
Data show that anti-human CD47 antibody B6H12 decreased expression of epidermal growth factor receptor (EGFR (show EGFR Antibodies)) and the stem cell transcription factors.
suggest that microglial activation may be partially caused by CD47/signal regulatory protein-alpha (show SIRPA Antibodies)- and CD200 (show CD200 Antibodies)/CD200R (show CD200R1 Antibodies)-mediated reductions in the immune inhibitory pathways
Our results highlight an underappreciated contribution of the adaptive immune system to anti-CD47 adjuvant therapy and suggest that targeting both innate and adaptive immune checkpoints can potentiate the vaccinal effect of antitumor antibody therapy.
Data suggest a reduction in the CD47 antigen/signal-regulatory protein alpha (show SIRPA Antibodies) (SIRPalpha) pathway by programmed cell death protein 1 (PD-1 (show PDCD1 Antibodies)) blockade, which regulates Myeloid-derived suppressor cells (MDSCs) and tumor associated macrophages (TAMs).
CD47 is a critical regulator in the metastasis of osteosarcoma and results suggest that targeted inhibition of this antigen by anti-CD47 may be a novel immunotherapeutic approach in the management of this tumor.
agents that block the CD47:SIRP (show SIRPA Antibodies)-alpha engagement are attractive therapeutic targets as a monotherapy or in combination with additional immune-modulating agents for activating antitumor T cells in vivo
CD47 is an adverse prognostic factor and promising therapeutic target in gastric cancer.
study demonstrates that antigen-presenting cells(CD47+) in coculture with human macrophages show a CD47 concentration-dependent inhibition of phagocytosis
CD47 expression contributes to the lethal breast cancer phenotype that is mediated by HIF-1 (show HIF1A Antibodies).
Amyloid-beta inhibits No-cGMP signaling in a CD36 (show CD36 Antibodies)- and CD47-dependent manner
Genetic induction of human CD47 on porcine cells could provide inhibitory signaling to SIRPalpha on human macrophages, providing a novel approach to preventing macrophage-mediated xenograft rejection.
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene.
, integrin-associated protein
, leukocyte surface antigen CD47
, CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
, CD47 glycoprotein
, antigen identified by monoclonal antibody 1D8
, antigenic surface determinant protein OA3
, integrin associated protein
, integrin-associated signal transducer
, CD47 antigen