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May act as a receptor in regulating T-cell proliferation.. Additionally we are shipping CD5 Antibodies (1298) and CD5 Proteins (19) and many more products for this protein.
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In mouse tumor models, CD5(+) but not CD5(-) B cells promoted tumor growth. The results demonstrate a critical role of CD5(+) B cells in promoting cancer.
CD5 and CD72 (show CD72 ELISA Kits) play a critical role in maintaining regulatory T and B cell homeostasis
CD5 promoted Treg cell induction in response to self and tolerizing antigens by blocking mTOR (show FRAP1 ELISA Kits) activation.
Data indicate that CD5-casein kinase 2 (CK2 (show CSNK2A1 ELISA Kits)) signaling is necessary for efficient nuclear localization of orphan nuclear receptor (show NR1D1 ELISA Kits) ROR (show RORB ELISA Kits)-gammaT (RORgammat).
These results support the notion that the distal cytoplasmic domain of CD5, including Y463, plays a relevant role in the downmodulation of TCR signals in thymocytes via c-Cbl (show CBL ELISA Kits).
Although the percentage of CD1d (show CD1D ELISA Kits)(hi)CD5+ subset in splenic B cells does not change significantly, percent IL-10 (show IL10 ELISA Kits)-expressing cells among total splenic B cells or the CD1dhiCD5+ population significantly increases 3-7 days after rCRT/39-272 administration
Different CD5 expression levels influence the proliferation dynamics of activated naive CD4 (show CD4 ELISA Kits)+ T cells while leaving the conversion rate of those cells into memory cells unaffected.
Data show several homologies across human, rat and mouse in the kinetic of loss of several LAgs such as CD5, CD4 (show CD4 ELISA Kits) and CD28 (show CD28 ELISA Kits).
CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn (show FYN ELISA Kits) kinase
Delayed tumor growth in CD5-deficient mice is associated with enhanced activation of tumor-infiltrating lymphocytes due to an upregulated T cell response to T cell receptor (TCR) stimulation.
This study confirms the poor prognosis of de novo CD5+ DLBCL in a large multi-center cohort despite initial rituximab-containing chemotherapy and suggests that stem cell transplantation fails to salvage the majority of these patients.
5.2 % were positive for CD5 and 5.7 % positive for epstein-Barr virus encoded RNA
CD5 polymorphisms are associated with systemic lupus erythematosus.
three tyrosine-based domains within CD5 cytoplasmic tail promote T-cell survival through non-overlapping mechanisms
A case of mantle cell lymphoma with a unique pattern of CD5 negative to positive expression switching in relapse.
Data show that the proportion of CD5+ B cells at 1 mo of age is inversely correlated to total IgG levels at 18 and 36 mo of age.
down-regulation of CD5 on activated CD8 (show CD8A ELISA Kits)(+) T cells may serve as a useful marker of dysregulated T cell activation and proliferation in FHL2 (show FHL2 ELISA Kits).
CD5 expression in nodal marginal zone lymphoma correlates with a higher frequency of dissemination, but patients have an indolent clinical course and excellent overall survival.
Our results indicate that CD5(+) B cell subsets might be associated with pathogenesis of SPMS.
Functional CD5-dependent casein kinase 2 signaling is necessary in a CD5 knock-in mouse for efficient differentiation of naive CD4 (show CD4 ELISA Kits)+ T cells into T helper (Th)2 and Th17 cells, but not Th1 (show TH1L ELISA Kits)-type cells.
Findings suggest that development, selection and function of different B- and T-cell subsets may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like (show CD5L ELISA Kits) molecules expressed on T cells compared to B (show TDO2 ELISA Kits) cells.
May act as a receptor in regulating T-cell proliferation.
, t-cell surface glycoprotein CD5-like
, T-cell surface glycoprotein CD5
, lymphocyte antigen 1
, CD5 antigen (p56-62)
, lymphocyte antigen T1/Leu-1
, CD5 antigen
, Lymphocyte antigen CD5
, CD74 antigen, invariant polypeptide of major
, lymphocyte receptor CD5