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glycosylphosphatidylinositol (GPI)-anchored cell surface antigen [RGD, Feb 2006].. Additionally we are shipping CD52 Antibodies (114) and CD52 Kits (9) and many more products for this protein.
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Rat (Rattus) CD52 Protein expressed in Human Cells - ABIN2009443
Buggins, Mufti, Salisbury, Codd, Westwood, Arno, Fishlock, Pagliuca, Devereux: Peripheral blood but not tissue dendritic cells express CD52 and are depleted by treatment with alemtuzumab. in Blood 2002
Soluble CD52 is used by certain CD4 (show CD4 Proteins)-positive cells to suppress target celss via the inhibitory receptor Siglec-10 (show SIGLEC10 Proteins).
Genetic background determines the requirement for B7 costimulation in autoimmunity induction. Backcrossed B7.1/B7.2 (show CD86 Proteins) deficient (-/-)mice on C57BL/6 (B6) or SJL backgrounds had different susceptibility to induced experimental autoimmune encephalomyelitis.
study examined the tissue distribution, molecular composition and immunogenicity of mouse male reproductive tract-CD52
The results indicate CD52 is not required for fertilization in the mouse either in vivo or in vitro.
Study helps to precisely define CD52 expression in the tumor cell population of PTCL and might therefore be valuable when evaluating the response to alemtuzumab therapy in prospective clinical trials.
CD52 is a novel prognostic NSC marker and a potential NSC target in a subset of patients with MDS (show PAFAH1B1 Proteins) and AML (show RUNX1 Proteins), which may have clinical implications and may explain clinical effects produced by alemtuzumab in these patients.
A molecular and computational diagnostic approach identifies FOXP3 (show FOXP3 Proteins), ICOS (show CTLA4 Proteins), CD52 and CASP1 (show CASP1 Proteins) as the most informative biomarkers in acute graft-versus-host disease.
CT60 single-nucleotide polymorphism of CTLA4 (show CTLA4 Proteins) is a surrogate marker for donor lymphocyte infusion outcome after allogeneic cell transplantation for acute leukemia
Clonal large granular lymphocytes exhibited decreased CD52 expression post-therapy in patients refractory to treatment.
Our bioinformatics findings suggest that CD52 polymorphism may affect the efficiency of GPI (show GNPDA1 Proteins) anchor formation and thus may indirectly alter the response to anti-CD52 agents like alemtuzumabin renal transplantation.
Review article on CD52 structure and function.
HE5(CD52) mRNA and protein, expressed in epithelial cells of the distal epididymis, were not affected by the obstruction of the vas (show AVP Proteins) deferens.
The relationship between this differential insertion and differences in glycosylation of rat and human CD52 is discussed.
CD52 is widely expressed on human mast cells (MCs (show SMCP Proteins)) and Waldenstrom's Macroglobulinemia bone marrow lymphoplasmacytic cells and provide the preclinical rationale for the use of alemtuzumab in the treatment of WM and possibly other MC-related disorders.
In this study, we identified the antigen of 4C8 mAb as CD52. CD52 is a costimulatory molecule (show CD276 Proteins) for induction of CD4 (show CD4 Proteins)-positive T cells.
glycosylphosphatidylinositol (GPI)-anchored cell surface antigen
, CD52 antigen
, CAMPATH-1 antigen
, lymphocyte differentiation antigen B7
, CD52 antigen (CAMPATH-1 antigen)
, CDW52 antigen (CAMPATH-1 antigen)
, cambridge pathology 1 antigen
, epididymal secretory protein E5
, human epididymis-specific protein 5