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The protein encoded by CD53 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping CD53 Proteins (8) and CD53 Kits (3) and many more products for this protein.
Showing 10 out of 136 products:
Human Monoclonal CD53 Primary Antibody for FACS - ABIN192137
Olweus, Lund-Johansen, Horejsi: CD53, a protein with four membrane-spanning domains, mediates signal transduction in human monocytes and B cells. in Journal of immunology (Baltimore, Md. : 1950) 1993
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Human Monoclonal CD53 Primary Antibody for Func, FACS - ABIN118730
Mollinedo, Martín-Martín, Gajate, Lazo: Physiological activation of human neutrophils down-regulates CD53 cell surface antigen. in Journal of leukocyte biology 1998
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Human Monoclonal CD53 Primary Antibody for FACS - ABIN303518
Puls, Hogquist, Reilly, Wright: CD53, a thymocyte selection marker whose induction requires a lower affinity TCR-MHC interaction than CD69, but is up-regulated with slower kinetics. in International immunology 2002
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Mouse (Murine) Monoclonal CD53 Primary Antibody for FACS - ABIN2664763
Angelisová, Hilgert, Horejsí: Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteins. in Immunogenetics 1994
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Mouse (Murine) Monoclonal CD53 Primary Antibody for FACS - ABIN2661774
Rasmussen, Blomhoff, Stokke, Horejsi, Smeland: Cross-linking of CD53 promotes activation of resting human B lymphocytes. in Journal of immunology (Baltimore, Md. : 1950) 1994
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Rat (Rattus) Monoclonal CD53 Primary Antibody for FACS, IHC (fro) - ABIN120494
Paterson, Green, Jefferies, Puklavec, Williams: The MRC OX-44 antigen marks a functionally relevant subset among rat thymocytes. in The Journal of experimental medicine 1987
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Human Monoclonal CD53 Primary Antibody for FACS, IHC (fro) - ABIN118729
Bazil, Stefanová, Hilgert, Kristofová, Van?k, Bukovský, Horejsí: Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. in Folia biologica 1990
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Human Monoclonal CD53 Primary Antibody for FACS - ABIN118728
Angelisová, Vlcek, Stefanová, Lipoldová, Horejsí: The human leucocyte surface antigen CD53 is a protein structurally similar to the CD37 and MRC OX-44 antigens. in Immunogenetics 1990
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Rat (Rattus) Monoclonal CD53 Primary Antibody for FACS - ABIN2661111
Lazo, Cuevas, Gutierrez del Arroyo, Orúe: Ligation of CD53/OX44, a tetraspan antigen, induces homotypic adhesion mediated by specific cell-cell interactions. in Cellular immunology 1997
CD53 has a role in macrophage protection against LPS (show TLR4 Antibodies)-induced oxidative stress and UVB irradiation
CD53 is associated with population asthma risk via the functional promoter polymorphism -1560 C>T.
SNP rs6679497 in gene CD53 showed significant association with TNFalpha (show TNF Antibodies) levels (P=0.001); no association of this SNP was observed with osteoarthritis
Ligation of CD53 triggers a survival response and reduces the number of cells that enter apoptosis. The CD53 antigen interactions might contribute to cell survival in poorly vascularized regions of the tumor mass.
Analysis of lymphocyte subsets showed that the total number of CD3 (show CD3 Antibodies)+, CD4 (show CD4 Antibodies)+, CD8 (show CD8A Antibodies)+ and CD56 (show NCAM1 Antibodies)+ lymphocytes increased after the intensive protocol before falling below pre-exercise values at 1 h post-exercise.
The paradox is that lymphocytes from RA patients are believed to resist apoptosis, and we suggest that the elevated expression of CD53, which results from the increased oxidative stress, may protect against apoptosis.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein.
cell surface glycoprotein CD53
, leukocyte surface antigen CD53
, CD53 antigen
, CD53 glycoprotein
, CD53 tetraspan antigen
, antigen MOX44 identified by monoclonal antibody MRC-OX44
, cell surface antigen
, transmembrane glycoprotein
, leukocyte antigen MRC OX-44