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anti-CD59a Antigen (CD59A) Antibodies

Potent inhibitor of the complement membrane attack complex (MAC) action. Additionally we are shipping CD59a Antigen Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD59A 12509 O55186
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Top anti-CD59a Antigen Antibodies at

Showing 5 out of 7 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Mouse PE FACS 100 μg Log in to see 10 to 12 Days
Mouse Mouse Un-conjugated FACS 100 μg Log in to see 10 to 12 Days
Mouse Mouse FITC Func, IA, FACS, IF, WB   100 μg Log in to see 5 to 6 Days
Mouse Rabbit Un-conjugated IHC (p), ELISA   100 μg Log in to see 16 Days
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days

CD59A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,

Top referenced anti-CD59a Antigen Antibodies

  1. Mouse (Murine) Monoclonal CD59A Primary Antibody for FACS - ABIN2664781 : Kohli, Levy: Resolvins and protectins: mediating solutions to inflammation. in British journal of pharmacology 2009 (PubMed)
    Show all 4 references for ABIN2664781

  2. Mouse (Murine) Monoclonal CD59A Primary Antibody for FACS - ABIN2662665 : Pu, Brodsky: Paroxysmal nocturnal hemoglobinuria from bench to bedside. in Clinical and translational science 2011 (PubMed)
    Show all 4 references for ABIN2662665

  3. Mouse (Murine) Monoclonal CD59A Primary Antibody for Func, IA - ABIN2191856 : Harris, Hanna, Mizuno, Holt, Marchbank, Morgan: Characterization of the mouse analogues of CD59 using novel monoclonal antibodies: tissue distribution and functional comparison. in Immunology 2003 (PubMed)
    Show all 3 references for ABIN2191856

More Antibodies against CD59a Antigen Interaction Partners

Mouse (Murine) CD59a Antigen (CD59A) interaction partners

  1. Varicella-zoster virus infection upregulates host CD59 (show CD59 Antibodies) expression in a tissue-specific manner.

  2. This study support a role of Cd59a (show CD59 Antibodies) in controlling the innate immune status of the RPE (show RPE Antibodies)-choroidal complex and emphasizes the particular vulnerability of this ocular compartment to the dysregulation of alternative complement pathway during aging

  3. results implicate CD59 (show CD59 Antibodies) as an important modulator of the immune response in NMO, and provide a novel animal model of NMO that closely recapitulates human NMO pathology.

  4. Soluble forms of CD59 (show CD59 Antibodies) (sCD59) have been investigated in mouse laser-induced choroidal neovascularization, a model for "wet" age related macular degeneration.

  5. both CD59 (show CD59 Antibodies) and C-PC could inhibit the progress of atherosclerosis, and the anti-atherosclerotic effects of C-PC might be fulfilled by promoting CD59 (show CD59 Antibodies) expression, preventing smooth muscle cell proliferation and the apoptosis of endothelial cells

  6. CD59a (show CD59 Antibodies) inhibits systemic autoimmunity in MRL/lpr (show FAS Antibodies) mice through a complement-independent mechanism.

  7. While the connection between CFH (show CFH Antibodies) deficiency and failure to upregulate CD59a (show CD59 Antibodies) remains unknown, these results suggest that expression of CD59 (show CD59 Antibodies) is tissue-specific and that neuroretinal regulation depends on CFH (show CFH Antibodies).

  8. Actively immunized experimental autoimmune myasthenia gravis mice deficient in either CD55 or CD59 showed significant differences in adaptive immune responses and worsened disease outcome associated with increased levels of serum cytokines, modified production of acetylcholine receptor antibodies, and more complement deposition at the neuromuscular junction.

  9. HBx can up-regulate CD59 (show CD59 Antibodies) and Crry (show CR1L Antibodies) expression in podocytes through activating the P38 (show CRK Antibodies) pathway.

  10. CD59 (show CD59 Antibodies) has a role in growth of the choroidal neovascular complex in mice

CD59a Antigen (CD59A) Antigen Profile

Protein Summary

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity).

Gene names and symbols associated with anti-CD59a Antigen (CD59A) Antibodies

  • CD59a antigen (Cd59a) antibody
  • AA987121 antibody
  • Cd59 antibody
  • protectin antibody

Protein level used designations for anti-CD59a Antigen (CD59A) Antibodies

CD59 antigen , CD59A glycoprotein , MAC-IP , MAC-inhibitory protein , MACIF , membrane attack complex inhibition factor

12509 Mus musculus
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