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CD59a Antigen Proteins (CD59A)

Potent inhibitor of the complement membrane attack complex (MAC) action. Additionally we are shipping CD59a Antigen Antibodies (7) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD59A 12509 O55186
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Top CD59a Antigen Proteins at

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse Fc Tag 50 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days

CD59A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Top referenced CD59a Antigen Proteins

  1. Mouse (Murine) CD59A Protein expressed in Human Cells - ABIN2008238 : Turnberg, Botto, Lewis, Zhou, Sacks, Morgan, Walport, Cook: CD59a deficiency exacerbates ischemia-reperfusion injury in mice. in The American journal of pathology 2004 (PubMed)

More Proteins for CD59a Antigen (CD59A) Interaction Partners

Mouse (Murine) CD59a Antigen (CD59A) interaction partners

  1. Varicella-zoster virus infection upregulates host CD59 (show CD59 Proteins) expression in a tissue-specific manner.

  2. This study support a role of Cd59a (show CD59 Proteins) in controlling the innate immune status of the RPE (show RPE Proteins)-choroidal complex and emphasizes the particular vulnerability of this ocular compartment to the dysregulation of alternative complement pathway during aging

  3. results implicate CD59 (show CD59 Proteins) as an important modulator of the immune response in NMO, and provide a novel animal model of NMO that closely recapitulates human NMO pathology.

  4. Soluble forms of CD59 (show CD59 Proteins) (sCD59) have been investigated in mouse laser-induced choroidal neovascularization, a model for "wet" age related macular degeneration.

  5. both CD59 (show CD59 Proteins) and C-PC could inhibit the progress of atherosclerosis, and the anti-atherosclerotic effects of C-PC might be fulfilled by promoting CD59 (show CD59 Proteins) expression, preventing smooth muscle cell proliferation and the apoptosis of endothelial cells

  6. CD59a (show CD59 Proteins) inhibits systemic autoimmunity in MRL/lpr (show FAS Proteins) mice through a complement-independent mechanism.

  7. While the connection between CFH (show CFH Proteins) deficiency and failure to upregulate CD59a (show CD59 Proteins) remains unknown, these results suggest that expression of CD59 (show CD59 Proteins) is tissue-specific and that neuroretinal regulation depends on CFH (show CFH Proteins).

  8. Actively immunized experimental autoimmune myasthenia gravis mice deficient in either CD55 or CD59 showed significant differences in adaptive immune responses and worsened disease outcome associated with increased levels of serum cytokines, modified production of acetylcholine receptor antibodies, and more complement deposition at the neuromuscular junction.

  9. HBx can up-regulate CD59 (show CD59 Proteins) and Crry (show CR1L Proteins) expression in podocytes through activating the P38 (show CRK Proteins) pathway.

  10. CD59 (show CD59 Proteins) has a role in growth of the choroidal neovascular complex in mice

CD59a Antigen (CD59A) Protein Profile

Protein Summary

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity).

Gene names and symbols associated with CD59a Antigen Proteins (CD59A)

  • CD59a antigen (Cd59a)
  • AA987121 protein
  • Cd59 protein
  • protectin protein

Protein level used designations for CD59a Antigen Proteins (CD59A)

CD59 antigen , CD59A glycoprotein , MAC-IP , MAC-inhibitory protein , MACIF , membrane attack complex inhibition factor

12509 Mus musculus
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