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CD6 encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. Additionally we are shipping CD6 Antibodies (227) and CD6 Kits (19) and many more products for this protein.
Showing 10 out of 14 products:
Mouse (Murine) CD6 Protein expressed in Human Cells - ABIN2008211
Singer, Fox, Haqqi, Beretta, Endres, Prohaska, Parnes, Bromberg, Sramkoski: CD6: expression during development, apoptosis and selection of human and mouse thymocytes. in International immunology 2002
Show all 2 references for ABIN2008211
Rat (Rattus) CD6 Protein expressed in Human Cells - ABIN2009464
Gimferrer, Ibáñez, Farnós, Sarrias, Fenutría, Roselló, Zimmermann, David, Vives, Serra-Pagès, Lozano: The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains. in Journal of immunology (Baltimore, Md. : 1950) 2005
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this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 Proteins)-Lat (show LAT Proteins)-SLP-76 (show LCP2 Proteins) network and thus should provide cues for future functional experiments.
The binding sites on CD6 and CD166 (show ALCAM Proteins) have been characterized to show that a SNP in CD6 causes glycosylation that hinders the CD6/CD166 (show ALCAM Proteins) interaction.
CD6 regulatory T cells are characterized by CD6 expression and FOXP3 (show FOXP3 Proteins) expression.
interaction of Galectin-1 (show LGALS1 Proteins) and -3 with CD6
upon T cell activation, SRSF1 (show SRSF1 Proteins) becomes limiting, and its function in CD6 exon 5 splicing is countered by an increase in CD6 transcription, dependent on chromatin acetylation.
The CD6 polymorphism conferred reduced odds of optic neuritis as an attack location
In a Korean population, one SNP in CD6 was associated with neuromyelitis optica.
Our findings reveal that this new MS-associated CD6 risk haplotype significantly modifies expression of CD6 on CD4 (show CD4 Proteins)(+) and CD8 (show CD8A Proteins)(+) T cells.
A novel level of regulation of CD6 function by intracytoplasmic serine phosphorylation.
Data suggest that genetic variations within CD6 and syntaxin binding protein 6 (STXBP6 (show STXBP6 Proteins)) may influence response to TNFalpha (show TNF Proteins) inhibitors in patients with rheumatoid arthritis (RA).
Cd6 is a signaling attenuator whose expression alone, i.e. in the absence of ligand engagement, is sufficient to restrain signaling in T cells.
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
T-cell differentiation antigen CD6
, CD6 antigen
, CD6 antigen, Tp120