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CD6 encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. Additionally we are shipping CD6 Antibodies (352) and CD6 Kits (14) and many more products for this protein.
Showing 10 out of 14 products:
Rat (Rattus) CD6 Protein expressed in Human Cells - ABIN2009464
Singer, Fox, Haqqi, Beretta, Endres, Prohaska, Parnes, Bromberg, Sramkoski: CD6: expression during development, apoptosis and selection of human and mouse thymocytes. in International immunology 2002
Show all 2 references for ABIN2009464
Mouse (Murine) CD6 Protein expressed in Human Cells - ABIN2008209
Gimferrer, Ibáñez, Farnós, Sarrias, Fenutría, Roselló, Zimmermann, David, Vives, Serra-Pagès, Lozano: The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains. in Journal of immunology (Baltimore, Md. : 1950) 2005
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this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 Proteins)-Lat (show LAT Proteins)-SLP-76 (show LCP2 Proteins) network and thus should provide cues for future functional experiments.
Results from recent genetic association studies provide evidence for a role of CD6 in multiple sclerosis and in rheumatoid arthritis pathogenesis. [review]
Study provides evidence on the role of CD6, a lymphocyte-specific surface receptor from to the ancient and highly conserved Scavenger Receptor Cysteine-Rich (SRCR) superfamily, as a pattern recognition receptor, and the functional consequences this may have on T cell activation and differentiation. [review]
Data show the multiple aspects that determine the nature of the signals transmitted via CD6 and the context that may define a dual role for this important T cell surface molecule (show CD8A Proteins). [review]
Data show a role for extracellular and intracellular interactions of CD6 in lateral movement in response to T cell activation. [review]
The binding sites on CD6 and CD166 (show ALCAM Proteins) have been characterized to show that a SNP in CD6 causes glycosylation that hinders the CD6/CD166 (show ALCAM Proteins) interaction.
CD6 regulatory T cells are characterized by CD6 expression and FOXP3 (show FOXP3 Proteins) expression.
interaction of Galectin-1 (show LGALS1 Proteins) and -3 with CD6
upon T cell activation, SRSF1 (show SRSF1 Proteins) becomes limiting, and its function in CD6 exon 5 splicing is countered by an increase in CD6 transcription, dependent on chromatin acetylation.
The CD6 polymorphism conferred reduced odds of optic neuritis as an attack location
In a Korean population, one SNP in CD6 was associated with neuromyelitis optica.
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
T-cell differentiation antigen CD6
, CD6 antigen
, CD6 antigen, Tp120