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CD6 Proteins (CD6)

CD6 encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. Additionally we are shipping CD6 Antibodies (344) and CD6 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD6 12511 Q61003
CD6 923 P30203
CD6 25752  
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Top CD6 Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Rat His tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Mouse Fc Tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$735.90
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$806.30
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CD6 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
, , ,
Human , ,
, , ,
Rat (Rattus) ,
,

Top referenced CD6 Proteins

  1. Rat (Rattus) CD6 Protein expressed in Human Cells - ABIN2009464 : Singer, Fox, Haqqi, Beretta, Endres, Prohaska, Parnes, Bromberg, Sramkoski: CD6: expression during development, apoptosis and selection of human and mouse thymocytes. in International immunology 2002 (PubMed)
    Show all 2 references for ABIN2009464

  2. Mouse (Murine) CD6 Protein expressed in Human Cells - ABIN2008209 : Gimferrer, Ibáñez, Farnós, Sarrias, Fenutría, Roselló, Zimmermann, David, Vives, Serra-Pagès, Lozano: The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 2 references for ABIN2008209

More Proteins for CD6 Interaction Partners

Mouse (Murine) CD6 interaction partners

  1. this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 Proteins)-Lat (show LAT Proteins)-SLP-76 (show LCP2 Proteins) network and thus should provide cues for future functional experiments.

Human CD6 interaction partners

  1. The binding sites on CD6 and CD166 (show ALCAM Proteins) have been characterized to show that a SNP in CD6 causes glycosylation that hinders the CD6/CD166 (show ALCAM Proteins) interaction.

  2. CD6 regulatory T cells are characterized by CD6 expression and FOXP3 (show FOXP3 Proteins) expression.

  3. interaction of Galectin-1 (show LGALS1 Proteins) and -3 with CD6

  4. upon T cell activation, SRSF1 (show SRSF1 Proteins) becomes limiting, and its function in CD6 exon 5 splicing is countered by an increase in CD6 transcription, dependent on chromatin acetylation.

  5. The CD6 polymorphism conferred reduced odds of optic neuritis as an attack location

  6. In a Korean population, one SNP in CD6 was associated with neuromyelitis optica.

  7. Our findings reveal that this new MS-associated CD6 risk haplotype significantly modifies expression of CD6 on CD4 (show CD4 Proteins)(+) and CD8 (show CD8A Proteins)(+) T cells.

  8. A novel level of regulation of CD6 function by intracytoplasmic serine phosphorylation.

  9. Data suggest that genetic variations within CD6 and syntaxin binding protein 6 (STXBP6 (show STXBP6 Proteins)) may influence response to TNFalpha (show TNF Proteins) inhibitors in patients with rheumatoid arthritis (RA).

  10. Cd6 is a signaling attenuator whose expression alone, i.e. in the absence of ligand engagement, is sufficient to restrain signaling in T cells.

CD6 Protein Profile

Protein Summary

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD6 Proteins (CD6)

  • CD6 antigen (Cd6)
  • CD6 molecule (CD6)
  • Cd6 molecule (Cd6)
  • OX52 protein
  • TP120 protein

Protein level used designations for CD6 Proteins (CD6)

T-cell differentiation antigen CD6 , CD6 antigen , T12 , CD6 antigen, Tp120

GENE ID SPECIES
12511 Mus musculus
923 Homo sapiens
25752 Rattus norvegicus
100513519 Sus scrofa
282881 Bos taurus
Selected quality suppliers for CD6 Proteins (CD6)
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