CD6 Proteins (CD6)

CD6 encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. Additionally we are shipping CD6 Antibodies (355) and CD6 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD6 12511 Q61003
CD6 923 P30203
CD6 25752  
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Top CD6 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_Human Cells Rat His tag 100 μg Log in to see 20 to 21 Days
$250.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$669.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$717.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$733.00
Details
HOST_Human Human Fc Tag SDS-PAGE 100 μg Log in to see 20 to 21 Days
$277.20
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 11 to 12 Days
$491.43
Details

CD6 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
, , ,
Human , , ,
, , , ,
Rat (Rattus) ,
,

Top referenced CD6 Proteins

  1. Mouse (Murine) CD6 Protein expressed in Human Cells - ABIN2008211 : Singer, Fox, Haqqi, Beretta, Endres, Prohaska, Parnes, Bromberg, Sramkoski: CD6: expression during development, apoptosis and selection of human and mouse thymocytes. in International immunology 2002 (PubMed)
    Show all 2 references for 2008211

  2. Rat (Rattus) CD6 Protein expressed in Human Cells - ABIN2009464 : Gimferrer, Ibáñez, Farnós, Sarrias, Fenutría, Roselló, Zimmermann, David, Vives, Serra-Pagès, Lozano: The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 2 references for 2009464

More Proteins for CD6 Interaction Partners

Mouse (Murine) CD6 interaction partners

  1. these data indicate that CD6 modulates the threshold for thymocyte selection and the generation and/or function of several peripheral T cell subpopulations, including T reg (show KCNH2 Proteins) cells

  2. results reveal an unexpected role of CD6 in the pathogenesis of intestinal IR-induced injury by regulating the self-renewal of B1a cells.

  3. this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 Proteins)-Lat (show LAT Proteins)-SLP-76 (show LCP2 Proteins) network and thus should provide cues for future functional experiments.

Human CD6 interaction partners

  1. Data indicate that the T cell-specific adaptor protein (TSAd (show SH2D2A Proteins)) SH2 domain interacts with CD6 antigen and linker for activation of T cells (show LAT Proteins) protein (LAT (show ORC3 Proteins)) phosphotyrosine (pTyr) peptides.

  2. Results from recent genetic association studies provide evidence for a role of CD6 in multiple sclerosis and in rheumatoid arthritis pathogenesis. [review]

  3. Study provides evidence on the role of CD6, a lymphocyte-specific surface receptor from to the ancient and highly conserved Scavenger Receptor Cysteine-Rich (SRCR) superfamily, as a pattern recognition receptor, and the functional consequences this may have on T cell activation and differentiation. [review]

  4. Data show the multiple aspects that determine the nature of the signals transmitted via CD6 and the context that may define a dual role for this important T cell surface molecule (show CD8A Proteins). [review]

  5. Data show a role for extracellular and intracellular interactions of CD6 in lateral movement in response to T cell activation. [review]

  6. The binding sites on CD6 and CD166 (show ALCAM Proteins) have been characterized to show that a SNP in CD6 causes glycosylation that hinders the CD6/CD166 (show ALCAM Proteins) interaction.

  7. CD6 regulatory T cells are characterized by CD6 expression and FOXP3 (show FOXP3 Proteins) expression.

  8. interaction of Galectin-1 (show LGALS1 Proteins) and -3 with CD6

  9. upon T cell activation, SRSF1 (show SRSF1 Proteins) becomes limiting, and its function in CD6 exon 5 splicing is countered by an increase in CD6 transcription, dependent on chromatin acetylation.

  10. The CD6 polymorphism conferred reduced odds of optic neuritis as an attack location

CD6 Protein Profile

Protein Summary

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD6 Proteins (CD6)

  • CD6 antigen (Cd6)
  • CD6 molecule (CD6)
  • Cd6 molecule (Cd6)
  • OX52 protein
  • TP120 protein

Protein level used designations for CD6 Proteins (CD6)

T-cell differentiation antigen CD6 , CD6 antigen , T12 , CD6 antigen, Tp120

GENE ID SPECIES
12511 Mus musculus
923 Homo sapiens
25752 Rattus norvegicus
100513519 Sus scrofa
282881 Bos taurus
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