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CD6 encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. Additionally we are shipping CD6 Antibodies (360) and CD6 Kits (15) and many more products for this protein.
Showing 9 out of 14 products:
Mouse (Murine) CD6 Protein expressed in Human Cells - ABIN2008209
Singer, Fox, Haqqi, Beretta, Endres, Prohaska, Parnes, Bromberg, Sramkoski: CD6: expression during development, apoptosis and selection of human and mouse thymocytes. in International immunology 2002
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Rat (Rattus) CD6 Protein expressed in Human Cells - ABIN2009464
Gimferrer, Ibáñez, Farnós, Sarrias, Fenutría, Roselló, Zimmermann, David, Vives, Serra-Pagès, Lozano: The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains. in Journal of immunology (Baltimore, Md. : 1950) 2005
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this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 Proteins)-Lat (show LAT Proteins)-SLP-76 (show LCP2 Proteins) network and thus should provide cues for future functional experiments.
Data indicate that the T cell-specific adaptor protein (TSAd (show SH2D2A Proteins)) SH2 domain interacts with CD6 antigen and linker for activation of T cells (show LAT Proteins) protein (LAT (show ORC3 Proteins)) phosphotyrosine (pTyr) peptides.
Results from recent genetic association studies provide evidence for a role of CD6 in multiple sclerosis and in rheumatoid arthritis pathogenesis. [review]
Study provides evidence on the role of CD6, a lymphocyte-specific surface receptor from to the ancient and highly conserved Scavenger Receptor Cysteine-Rich (SRCR) superfamily, as a pattern recognition receptor, and the functional consequences this may have on T cell activation and differentiation. [review]
Data show the multiple aspects that determine the nature of the signals transmitted via CD6 and the context that may define a dual role for this important T cell surface molecule (show CD8A Proteins). [review]
Data show a role for extracellular and intracellular interactions of CD6 in lateral movement in response to T cell activation. [review]
The binding sites on CD6 and CD166 (show ALCAM Proteins) have been characterized to show that a SNP in CD6 causes glycosylation that hinders the CD6/CD166 (show ALCAM Proteins) interaction.
CD6 regulatory T cells are characterized by CD6 expression and FOXP3 (show FOXP3 Proteins) expression.
interaction of Galectin-1 (show LGALS1 Proteins) and -3 with CD6
upon T cell activation, SRSF1 (show SRSF1 Proteins) becomes limiting, and its function in CD6 exon 5 splicing is countered by an increase in CD6 transcription, dependent on chromatin acetylation.
The CD6 polymorphism conferred reduced odds of optic neuritis as an attack location
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
T-cell differentiation antigen CD6
, CD6 antigen
, CD6 antigen, Tp120