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CD62E/CD62P encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells.
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P-Selectin (show SELP Antibodies) and ICAM-1 (show ICAM1 Antibodies) have roles in mediating THP-1 (show GLI2 Antibodies) monocyte adhesion
Transgenic expression of SELP (show SEPP1 Antibodies) is atherogenic in Apoe (show APOE Antibodies)(-/-) mice, suggesting that P-selectin (show SELP Antibodies) contributes to atherogenesis.
These results provide a novel insight into the mechano-chemical regulation mechanism for P-selectin (show SELP Antibodies)-induced calcium signaling of neutrophils in flow.
Data indicate no association of maternal or fetal ITGA2 (show ITGA2 Antibodies) C807T SNP, ITGB3 (show ITGB3 Antibodies) T1565C SNP, PECAM1 (show PECAM1 Antibodies) CTG - GTG (show GGT1 Antibodies) and SELP (show SEPP1 Antibodies) A/C polymorphisms with fetal growth restriction (FGR (show FGR Antibodies)).
Study concluded that the genotype and allele frequencies of SELP (show SEPP1 Antibodies) S290N were not significant different between the acute ischemic stroke case group and the control group as well as between each subtype group and the control group
High SELP (show SEPP1 Antibodies) expression is associated with Inflamed Atherosclerotic Plaque.
Circulating P-selectin (show SELP Antibodies) levels were closely associated with endocan (show ESM1 Antibodies) levels in obese children and adolescents with non-alcoholic fatty liver disease.
Primary Aldosteronism is related to platelet activation, expressed as higher plasma values of soluble CD40L (show CD40LG Antibodies) and soluble P-selectin (show SELP Antibodies) values.
Immobilized P-selectin (show SELP Antibodies)-induced calcium signaling of HL-60 cells is P-selectin (show SELP Antibodies) concentration- and mechanical force-dependent
results found that LMWF protected the renal function in diabetic nephropathy rats and alleviated inflammation through the modulation of P-selectin (show SELP Antibodies) and inflammatory cytokines. LMWF may have therapeutic potential against diabetic nephropathy.
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
CD62 antigen-like family member P
, granule membrane protein 140
, granulocyte membrane protein
, leukocyte-endothelial cell adhesion molecule 3
, platelet activation dependent granule-external membrane protein
, platelet alpha-granule membrane protein