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CD62E/CD62P encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells.
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Human Monoclonal CD62E/CD62P Primary Antibody for IHC (fro), FACS - ABIN2472222
Thornhill, Haskard: IL-4 regulates endothelial cell activation by IL-1, tumor necrosis factor, or IFN-gamma. in Journal of immunology (Baltimore, Md. : 1950) 1990
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Human Monoclonal CD62E/CD62P Primary Antibody for FACS - ABIN2472224
Kyan-Aung, Haskard, Poston, Thornhill, Lee et al.: Endothelial leukocyte adhesion molecule-1 and intercellular adhesion molecule-1 mediate the adhesion of eosinophils to endothelial cells in vitro and are expressed by endothelium in allergic ... in Journal of immunology (Baltimore, Md. : 1950) 1991
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The addition of sialic acid enhances the affinity of CD15 (show FUT4 Antibodies) to P-selectin (show SELP Antibodies) and augments the cell adhesion to blood vessel endothelial cells.
This study provides a better understanding of the biology of P-selectin (show SELP Antibodies) and PSGL-1 (show SELPLG Antibodies) and their roles in dissemination and resensitization of Multiple myeloma treatment.
Data (including data from studies in transgenic mice) suggest that sequence variations limited to 1.4-kb proximal promoter region account for most differences in expression of murine Selp (show SEPP1 Antibodies) and human SELP (show SEPP1 Antibodies) genes.
P-selectin (show SELP Antibodies) gene polymorphisms and haplotypes can contribute to proliferative diabetic retinopathy development.
P-selectin (show SELP Antibodies) polymorphism of -825T/C is associated with the risk of pulmonary hypertension in congenital heart defects, and may be one of its risk factors.
Soluble P-selectin (show SELP Antibodies) was upregulated I ankylosing spondylitis patients could predict prognosis.
P-selectin (show SELP Antibodies) has a role in endothelial progenitor cells' inhibition of platelet function
s. Leukocyte filtration does not affect the CD62P (show SELP Antibodies) surface expression of apheresis platelets stored for up to 2 days, which indicates that leukocyte filtration does not damage the activation of apheresis platelets within the retention period
Plasmodium falciparum MSP7 and P-selectin (show SELP Antibodies) were shown to bind each other directly via the N-terminus of PfMSP7 and the P-selectin (show SELP Antibodies) C-type lectin (show MBL2 Antibodies) and EGF (show EGF Antibodies)-like domains.
CD62P (show SELP Antibodies) levels may be useful as a sensitive clinical marker for the early detection of DWMLs [deep white matter lesions]with cognitive decline.
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
CD62 antigen-like family member P
, granule membrane protein 140
, granulocyte membrane protein
, leukocyte-endothelial cell adhesion molecule 3
, platelet activation dependent granule-external membrane protein
, platelet alpha-granule membrane protein