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CD63 Molecule Proteins (CD63)

The protein encoded by CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping CD63 Antibodies (322) and CD63 Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD63 12512 P41731
CD63 967 P08962
CD63 29186 P28648
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Top CD63 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Cynomolgus His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Human Cells Wild boar Fc Tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$880.00
Details

CD63 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
, ,
Human , , , ,
, ,
Rat (Rattus)
,

Top referenced CD63 Proteins

  1. Rat (Rattus) CD63 Protein expressed in Human Cells - ABIN2009448 : Smith, Bleijs, Radford, Hersey: Immunogenicity of CD63 in a patient with melanoma. in Melanoma research 1998 (PubMed)
    Show all 2 references for ABIN2009448

  2. Cynomolgus CD63 Protein expressed in Human Cells - ABIN2009966 : Källquist, Hansson, Persson, Janssen, Calafat, Tapper, Olsson: The tetraspanin CD63 is involved in granule targeting of neutrophil elastase. in Blood 2008 (PubMed)
    Show all 2 references for ABIN2009966

More Proteins for CD63 Molecule (CD63) Interaction Partners

Mouse (Murine) CD63 Molecule (CD63) interaction partners

  1. Data show that CD63 is a crucial player in the regulation of the tumor cell-intrinsic metastatic potential by affecting cell plasticity.

  2. These findings identify CD63 as an important component of allergic inflammation.

  3. CD63 serves to bridge between beta1 integrin and VEGFR2 (show KDR Proteins) because CD63 silencing disrupted VEGFR2 (show KDR Proteins)-beta1 integrin complex formation identified using proximity ligation assay

  4. Loss of CD63 is associated impairment of amyloidogenesis and downstream melanosome morphogenesis.

  5. Loss of CD63 has a similar phenotype to loss of P-selectin (show SELP Proteins) itself, thus CD63 is an essential cofactor to P-selectin (show SELP Proteins).

  6. CXCR4 (show CXCR4 Proteins) can be downregulated on activated B cells by IL-21 (show IL21 Proteins)-induced endocytosis and CD63-mediated endosomal recruitment.

  7. The findings identify palmitoylation-dependent association with the tetraspanin CD63 as the mechanism by which Syt VII (show SYT7 Proteins) is targeted to lysosomes.

  8. CD63, but not RILP (show RILP Proteins), is recruited to the phagosomes in macrophages expressing the dominant negative form of Rab7 (show RAB7A Proteins).

  9. CD63 is recruited to already-budded Weibel-Palade bodies by an AP-3-dependent route

  10. Upon phagocytosis of Cryptococcus neoformans and polystyrene beads, CD63 was recruited selectively to C. neoformans-containing phagosomes in a MyD88 (show MYD88 Proteins)-independent acidification-dependent manner

Human CD63 Molecule (CD63) interaction partners

  1. CD163 (show CD163 Proteins)(+) TAMs in oral premalignant lesions coexpress CD163 (show CD163 Proteins) and STAT1 (show STAT1 Proteins), suggesting that the TAMs in oral premalignant lesions possess an M1 phenotype in a Th1 (show TH1L Proteins)-dominated micromilieu.

  2. Our findings reveal that elevated levels of TIMP-1 (show TIMP1 Proteins) impact on neutrophil homeostasis via signaling through CD63.

  3. These findings indicate that rhTIMP-1 promotes clonogenic expansion and survival in human progenitors via the activation of the CD63/PI3K (show PIK3CA Proteins)/pAkt (show AKT1 Proteins) signaling pathway

  4. It was shown that treatment of macrophages with anti-CD63 inhibits CCR5-mediated virus infection in a cell type-specific manner, but that no inhibition of CXCR4 (show CXCR4 Proteins)-tropic viruses occurs.

  5. TM4SF5 interacted with CD151 (show CD151 Proteins), and caused the internalization of CD63 from the cell surface.

  6. Diesel exhaust exposure during exercise induces platelet activation as illustrated by a dose-response increase in the release of CD62P (show SELP Proteins) and CD63.

  7. Data show that CD63 is a crucial player in the regulation of the tumor cell-intrinsic metastatic potential by affecting cell plasticity.

  8. CD63 tetraspanin is a negative driver of epithelial-to-mesenchymal transition in human melanoma cells.

  9. these results indicated that high glycosylation of CD63 by RPN2 (show PSMD1 Proteins) is implicated in clinical outcomes in breast cancer patients

  10. CD9 (show CD9 Proteins) and CD63 tetraspanins block HIV-1-induced cell-cell fusion at the transition from hemifusion to pore opening.

CD63 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Gene names and symbols associated with CD63 Molecule Proteins (CD63)

  • CD63 antigen (Cd63)
  • CD63 antigen (LOC100155929)
  • CD63 antigen-like (LOC100051450)
  • CD63 molecule (CD63)
  • Cd63 molecule (Cd63)
  • CD63 molecule (Cd63)
  • C75951 protein
  • LAMP-3 protein
  • ME491 protein
  • MLA1 protein
  • OMA81H protein
  • TSP29FA protein
  • TSPAN30 protein

Protein level used designations for CD63 Molecule Proteins (CD63)

melanoma 1 antigen , CD63 antigen , CD63 antigen (melanoma 1 antigen) , granulophysin , lysosomal-associated membrane protein 3 , lysosome-associated membrane glycoprotein 3 , melanoma-associated antigen ME491 , melanoma-associated antigen MLA1 , ocular melanoma-associated antigen , tetraspanin-30 , tspan-30 , ME491/CD63 antigen , mast cell antigen AD1

GENE ID SPECIES
12512 Mus musculus
100155929 Sus scrofa
100051450 Equus caballus
967 Homo sapiens
404156 Bos taurus
493846 Felis catus
100008988 Oryctolagus cuniculus
29186 Rattus norvegicus
474391 Canis lupus familiaris
101114944 Ovis aries
100716198 Cavia porcellus
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