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CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. Additionally we are shipping CD68 Antibodies (396) and CD68 Proteins (26) and many more products for this protein.
Showing 10 out of 18 products:
Rat (Rattus) CD68 ELISA Kit for Sandwich ELISA - ABIN457212
Schlegel, Graf, Clavien, Dutkowski: Hypothermic oxygenated perfusion (HOPE) protects from biliary injury in a rodent model of DCD liver transplantation. in Journal of hepatology 2013
CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver.
Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age
Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 (show CCR7 ELISA Kits) / CD68 emigration pathway in macrophages
These findings demonstrate a role for CD68 in the function of osteoclasts.
CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking.
Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques.
Macrosialin does not function as an oxLDL receptor on the cell surface.
Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice.
The strong CD68 and S100 co-expression in our case did not allow a clear-cut discrimination between the immunophenotype of histiocytic neoplasms and amelanotic melanoma, because of CD68 immunoreactivity occurring in 75% of metastatic malignant melanomas
Using double labeling with Iba-1 (show AIF1 ELISA Kits) and cd68 could determine the physiological state of microglia in brain contusion based on their morphology and immunoreactivity.
we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1 (show FOLR1 ELISA Kits), FOLR2 (show FOLR2 ELISA Kits), CD68 and CD11b (show ITGAM ELISA Kits) markers
Inhibitory Profile of Liver CD68+ Cells during HCV Infection as Observed by an Increased CD80 (show CD80 ELISA Kits) and PD-L1 (show CD274 ELISA Kits) but Not CD86 (show CD86 ELISA Kits) Expression
Microenvironment CD20 (show MS4A1 ELISA Kits) + cells seem to play a favorable prognostic role in classical Hodgkin Lymphoma. Depletion of CD20 (show MS4A1 ELISA Kits) + cells together with an increase of TAMs identifies a group of patients with high-risk disease.
Data indicate the prognostic value of CD68 antigen in Hodgkin lymphoma (HL).
This study does not support a prognostic role of CD68 positivity in predicting survival.
we raised a possibility that the microlocalization of CD68(+) tumor-associated macrophages was an indispensable factor for the advance of oral squamous cell carcinoma.
Data indicate that the high CD68/CD3 (show CD3 ELISA Kits) ratio identifies a bad prognosis group among muscle-invasive urothelial carcinoma (UC).
The human CD68 promoter drives green fluorescent protein expression in all CD115 (show CSF1R ELISA Kits)(+) monocytes of adult blood, spleen, and bone marrow.
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
, CD68 antigen
, macrophage antigen CD68
, scavenger receptor class D, member 1