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CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. Additionally we are shipping CD68 Antibodies (401) and CD68 Kits (21) and many more products for this protein.
Showing 10 out of 26 products:
Human CD68 Protein expressed in HEK-293 Cells - ABIN2180823
Kunisch, Fuhrmann, Roth, Winter, Lungershausen, Kinne: Macrophage specificity of three anti-CD68 monoclonal antibodies (KP1, EBM11, and PGM1) widely used for immunohistochemistry and flow cytometry. in Annals of the rheumatic diseases 2004
Show all 4 references for ABIN2180823
Human CD68 Protein expressed in Escherichia coli (E. coli) - ABIN1098674
Shun, Yeh, Chang, Wu, Lien, Chen, Wang, Chia: Activation of human valve interstitial cells by a viridians streptococci modulin induces chemotaxis of mononuclear cells. in The Journal of infectious diseases 2009
Show all 2 references for ABIN1098674
Rat (Rattus) CD68 Protein expressed in Human Cells - ABIN2009458
Sadovnikova, Parovichnikova, Savchenko, Zabotina, Stauss: The CD68 protein as a potential target for leukaemia-reactive CTL. in Leukemia 2002
Show all 2 references for ABIN2009458
Human CD68 Protein expressed in Baculovirus infected Insect Cells - ABIN2004072
Strojnik, Kavalar, Zajc, Diamandis, Oikonomopoulou, Lah: Prognostic impact of CD68 and kallikrein 6 in human glioma. in Anticancer research 2009
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CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver.
Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age
Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 (show CCR7 Proteins) / CD68 emigration pathway in macrophages
These findings demonstrate a role for CD68 in the function of osteoclasts.
CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking.
Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques.
Macrosialin does not function as an oxLDL receptor on the cell surface.
Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice.
Using double labeling with Iba-1 (show AIF1 Proteins) and cd68 could determine the physiological state of microglia in brain contusion based on their morphology and immunoreactivity.
we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1 (show FOLR1 Proteins), FOLR2 (show FOLR2 Proteins), CD68 and CD11b (show ITGAM Proteins) markers
Inhibitory Profile of Liver CD68+ Cells during HCV Infection as Observed by an Increased CD80 (show CD80 Proteins) and PD-L1 (show CD274 Proteins) but Not CD86 (show CD86 Proteins) Expression
Microenvironment CD20 (show MS4A1 Proteins) + cells seem to play a favorable prognostic role in classical Hodgkin Lymphoma. Depletion of CD20 (show MS4A1 Proteins) + cells together with an increase of TAMs identifies a group of patients with high-risk disease.
Data indicate the prognostic value of CD68 antigen in Hodgkin lymphoma (HL).
This study does not support a prognostic role of CD68 positivity in predicting survival.
we raised a possibility that the microlocalization of CD68(+) tumor-associated macrophages was an indispensable factor for the advance of oral squamous cell carcinoma.
Data indicate that the high CD68/CD3 (show CD3 Proteins) ratio identifies a bad prognosis group among muscle-invasive urothelial carcinoma (UC).
The human CD68 promoter drives green fluorescent protein expression in all CD115 (show CSF1R Proteins)(+) monocytes of adult blood, spleen, and bone marrow.
CD68 tumor-associated macrophage marker is not prognostic of clinical outcome in classical Hodgkin lymphoma.
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
, CD68 antigen
, macrophage antigen CD68
, scavenger receptor class D, member 1