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CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. Additionally we are shipping CD68 Proteins (32) and CD68 Kits (22) and many more products for this protein.
Showing 10 out of 587 products:
Human Monoclonal CD68 Primary Antibody for ICC, FACS - ABIN152106
Horny, Schaumburg-Lever, Bolz, Geerts, Kaiserling: Use of monoclonal antibody KP1 for identifying normal and neoplastic human mast cells. in Journal of clinical pathology 1990
Show all 31 references for ABIN152106
Mouse (Murine) Monoclonal CD68 Primary Antibody for FACS - ABIN181838
Kirby, Beattie, Maroof, van Rooijen, Kaye: SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages. in The American journal of pathology 2009
Show all 13 references for ABIN181838
Mouse (Murine) Monoclonal CD68 Primary Antibody for FACS, IHC (fro) - ABIN181837
Frossard, Lenglet, Montecucco, Steffens, Galan, Pelli, Spahr, Mach, Hadengue: Role of CCL-2, CCR-2 and CCR-4 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury. in Journal of clinical pathology 2011
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Cow (Bovine) Monoclonal CD68 Primary Antibody for FACS - ABIN111832
Bauer, Sminia, Wouterlood, Dijkstra: Phagocytic activity of macrophages and microglial cells during the course of acute and chronic relapsing experimental autoimmune encephalomyelitis. in Journal of neuroscience research 1994
Show all 11 references for ABIN111832
Mouse (Murine) Monoclonal CD68 Primary Antibody for FACS - ABIN181834
West, Pearson, Barker, Luhmann, Maclaren, Barber, Duran, Smith, Sowden, Ali: Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation. in Stem cells (Dayton, Ohio) 2010
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Rat (Rattus) Monoclonal CD68 Primary Antibody for FACS, IHC (fro) - ABIN319454
Schneider, Meusel, Renker, Bauer, Holzinger, Roeder, Wanner, Gekle, Sauvant: Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome. in American journal of physiology. Renal physiology 2009
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Rat (Rattus) Monoclonal CD68 Primary Antibody for FACS - ABIN111833
Dijkstra, Döpp, Joling, Kraal: The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. in Immunology 1985
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Human Monoclonal CD68 Primary Antibody for FACS - ABIN112006
Diop, Gueye, Dias-Tavares, Kornfeld, Faye, Ave, Huerre, Corbet, Barre-Sinoussi, Müller-Trutwin: High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys. in Journal of virology 2000
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Mouse (Murine) Monoclonal CD68 Primary Antibody for FACS - ABIN181833
Ramprasad, Terpstra, Kondratenko, Quehenberger, Steinberg: Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. in Proceedings of the National Academy of Sciences of the United States of America 1997
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Human Monoclonal CD68 Primary Antibody for IHC (p) - ABIN114506
Falini, Flenghi, Pileri, Gambacorta, Bigerna, Durkop, Eitelbach, Thiele, Pacini, Cavaliere: PG-M1: a new monoclonal antibody directed against a fixative-resistant epitope on the macrophage-restricted form of the CD68 molecule. in The American journal of pathology 1993
CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver.
Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age
Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 (show CCR7 Antibodies) / CD68 emigration pathway in macrophages
These findings demonstrate a role for CD68 in the function of osteoclasts.
CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking.
Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques.
Macrosialin does not function as an oxLDL receptor on the cell surface.
Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice.
The strong CD68 and S100 co-expression in our case did not allow a clear-cut discrimination between the immunophenotype of histiocytic neoplasms and amelanotic melanoma, because of CD68 immunoreactivity occurring in 75% of metastatic malignant melanomas
Using double labeling with Iba-1 (show AIF1 Antibodies) and cd68 could determine the physiological state of microglia in brain contusion based on their morphology and immunoreactivity.
we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1 (show FOLR1 Antibodies), FOLR2 (show FOLR2 Antibodies), CD68 and CD11b (show ITGAM Antibodies) markers
Inhibitory Profile of Liver CD68+ Cells during HCV Infection as Observed by an Increased CD80 (show CD80 Antibodies) and PD-L1 (show CD274 Antibodies) but Not CD86 (show CD86 Antibodies) Expression
Microenvironment CD20 (show MS4A1 Antibodies) + cells seem to play a favorable prognostic role in classical Hodgkin Lymphoma. Depletion of CD20 (show MS4A1 Antibodies) + cells together with an increase of TAMs identifies a group of patients with high-risk disease.
Data indicate the prognostic value of CD68 antigen in Hodgkin lymphoma (HL).
This study does not support a prognostic role of CD68 positivity in predicting survival.
we raised a possibility that the microlocalization of CD68(+) tumor-associated macrophages was an indispensable factor for the advance of oral squamous cell carcinoma.
Data indicate that the high CD68/CD3 (show CD3 Antibodies) ratio identifies a bad prognosis group among muscle-invasive urothelial carcinoma (UC).
The human CD68 promoter drives green fluorescent protein expression in all CD115 (show CSF1R Antibodies)(+) monocytes of adult blood, spleen, and bone marrow.
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
, CD68 antigen
, macrophage antigen CD68
, scavenger receptor class D, member 1