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CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. Additionally we are shipping CD68 Proteins (33) and CD68 Kits (31) and many more products for this protein.
Showing 10 out of 630 products:
Mouse (Murine) Monoclonal CD68 Primary Antibody for FACS - ABIN181838
Kirby, Beattie, Maroof, van Rooijen, Kaye: SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages. in The American journal of pathology 2009
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Mouse (Murine) Monoclonal CD68 Primary Antibody for FACS, IHC (fro) - ABIN181837
Frossard, Lenglet, Montecucco, Steffens, Galan, Pelli, Spahr, Mach, Hadengue: Role of CCL-2, CCR-2 and CCR-4 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury. in Journal of clinical pathology 2011
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Human Polyclonal CD68 Primary Antibody for IF (cc), IF (p) - ABIN671406
Zeng, Zhang, Li, Yang, Chen, Liu: A new method to isolate and culture rat kupffer cells. in PLoS ONE 2013
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Cow (Bovine) Monoclonal CD68 Primary Antibody for FACS - ABIN111832
Bauer, Sminia, Wouterlood, Dijkstra: Phagocytic activity of macrophages and microglial cells during the course of acute and chronic relapsing experimental autoimmune encephalomyelitis. in Journal of neuroscience research 1994
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Mouse (Murine) Monoclonal CD68 Primary Antibody for FACS - ABIN181834
West, Pearson, Barker, Luhmann, Maclaren, Barber, Duran, Smith, Sowden, Ali: Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation. in Stem cells (Dayton, Ohio) 2010
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Rat (Rattus) Monoclonal CD68 Primary Antibody for FACS - ABIN111833
Dijkstra, Döpp, Joling, Kraal: The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. in Immunology 1985
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Human Monoclonal CD68 Primary Antibody for FACS - ABIN112006
Diop, Gueye, Dias-Tavares, Kornfeld, Faye, Ave, Huerre, Corbet, Barre-Sinoussi, Müller-Trutwin: High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys. in Journal of virology 2000
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Human Polyclonal CD68 Primary Antibody for FACS, IF (p) - ABIN686467
Hu, Shi, Jiang, Han, Huang, Jiang: Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: preparation, characterization and efficacy in Parkinson's disease. in International journal of pharmaceutics 2011
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Mouse (Murine) Monoclonal CD68 Primary Antibody for FACS - ABIN181833
Ramprasad, Terpstra, Kondratenko, Quehenberger, Steinberg: Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. in Proceedings of the National Academy of Sciences of the United States of America 1997
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Human Monoclonal CD68 Primary Antibody for IHC (p) - ABIN114506
Falini, Flenghi, Pileri, Gambacorta, Bigerna, Durkop, Eitelbach, Thiele, Pacini, Cavaliere: PG-M1: a new monoclonal antibody directed against a fixative-resistant epitope on the macrophage-restricted form of the CD68 molecule. in The American journal of pathology 1993
Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities.
Myeloid osteoclast precursors do not express CD68.
CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver.
Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age
Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 (show CCR7 Antibodies) / CD68 emigration pathway in macrophages
These findings demonstrate a role for CD68 in the function of osteoclasts.
CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking.
Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques.
Macrosialin does not function as an oxLDL receptor on the cell surface.
Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice.
Most cases of histiocytic sarcoma expressed histiocytic markers CD68 (6 of 7 cases), CD163 (show CD163 Antibodies) (5 of 5 cases), and PU.1 (3 of 4 cases).
Renal expression of CD68 and the chronicity index are associated with progression to chronic kidney disease in patients with proliferative lupus nephritis.
Results indicate that the expression of FoxP3 (show FOXP3 Antibodies) was not significantly associated with survival, and suggest prognostic significance of high CD68 expression in primary central nervous system lymphoma (PCNSL).
Her-2 (show ERBB2 Antibodies) overexpression results in ICA were similar to previous reports, the finding of 28% in HGD (show HGD Antibodies) was unexpected and may have clinical implications. Positive Her-2 (show ERBB2 Antibodies) DISH in 6% of LGD is novel, suggesting a role of Her-2 (show ERBB2 Antibodies) during BE progression
CD68 may play key roles in the pathogenesis of Alzheimer's disease (AD) and its complications may be via induction of inflammation; CD68 may be considered as a risk factor for development of AD and also psychotic symptoms in the patients
hCD68GFP/ApoE (show APOE Antibodies)(-/-) mice provide a new approach to study macrophage accumulation in atherosclerotic plaque progression and to identify cells recruited from adoptively transferred monocytes.
The strong CD68 and S100 co-expression in our case did not allow a clear-cut discrimination between the immunophenotype of histiocytic neoplasms and amelanotic melanoma, because of CD68 immunoreactivity occurring in 75% of metastatic malignant melanomas
Using double labeling with Iba-1 (show AIF1 Antibodies) and cd68 could determine the physiological state of microglia in brain contusion based on their morphology and immunoreactivity.
we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1 (show FOLR1 Antibodies), FOLR2 (show FOLR2 Antibodies), CD68 and CD11b (show ITGAM Antibodies) markers
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
, CD68 antigen
, macrophage antigen CD68
, scavenger receptor class D, member 1