anti-CD68 Molecule (CD68) Antibodies

CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. Additionally we are shipping CD68 Kits (33) and CD68 Proteins (26) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD68 12514 P31996
CD68 287435  
CD68 968 P34810
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Top anti-CD68 Antibodies at antibodies-online.com

Showing 10 out of 642 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Guinea Pig Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit <br /> Target Name: CD68 <br /> Sample Tissue: Human 293T <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rat Un-conjugated FACS, IHC (fro), IF, IHC (p), IP, WB Staining of permeabilised mouse peritoneal macrophages with RAT ANTI MOUSE CD68 (ABIN181837). 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Cow Mouse FITC FACS Staining of rat peritoneal macrophages cells with MOUSE PERMEABILISED ANTI RAT CD68:FITC 0.1 mg Log in to see 6 to 8 Days
$753.50
Details
Rat Mouse PE FACS Staining of permeabilised rat peritoneal macrophages cells with MOUSE ANTI RAT CD68:RPE (ABIN111833). 100 Tests Log in to see 6 to 8 Days
$764.50
Details
Human Mouse FITC FACS Staining of human peripheral blood monocytes with mouse anti human CD68: FITC (ABIN112006) following permeabilisation 100 Tests Log in to see 6 to 8 Days
$434.50
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat myocardium tissue labeled Anti-CD68 Polyclonal Antibody, unconjugated  (ABIN671406)  at 1: 200, followed by incubation with conjugated secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat myocardium labeled with Anti-MuRF1/Trim63 Polyclonal Antibody, Unconjugated (ABIN671406) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB This image was generously provided by Amanda Brown, Ph.D. from Johns Hopkins University School of Medicine. Paraffin embedded human brain tissue labeled with Rabbit Anti-CD68 Polyclonal Antibody, Unconjugated  at 1:50 followed by conjugation to the secondary antibody and Permanent Fast Red Quanto staining Human U937 cells probed with CD68 Polyclonal Antibody, Unconjugated  at 1:100 for 30 minutes followed by incubation with a PE Conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse Un-conjugated IHC (p)   0.5 mL Log in to see 6 to 8 Days
$357.50
Details
Mouse Rat FITC FACS Staining of permeabilised mouse peritoneal macrophages 0.1 mg Log in to see 6 to 8 Days
$423.50
Details

CD68 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CD68 Antibodies

  1. Mouse (Murine) Monoclonal CD68 Primary Antibody for FACS, ICC - ABIN4295377 : Robertson, OConnell, Hudson, Seamark: Granulocyte-macrophage colony-stimulating factor (GM-CSF) targets myeloid leukocytes in the uterus during the post-mating inflammatory response in mice. in Journal of reproductive immunology 2000 (PubMed)
    Show all 24 Pubmed References

  2. Human Monoclonal CD68 Primary Antibody for ICC, FACS - ABIN152106 : Horny, Schaumburg-Lever, Bolz, Geerts, Kaiserling: Use of monoclonal antibody KP1 for identifying normal and neoplastic human mast cells. in Journal of clinical pathology 1990 (PubMed)
    Show all 33 Pubmed References

  3. Human Monoclonal CD68 Primary Antibody for ICC, IHC (fro) - ABIN256057 : da Costa, Annels, Faaij, Forsyth, Hogendoorn, Egeler: Presence of osteoclast-like multinucleated giant cells in the bone and nonostotic lesions of Langerhans cell histiocytosis. in The Journal of experimental medicine 2005 (PubMed)
    Show all 15 Pubmed References

  4. Human Monoclonal CD68 Primary Antibody for FACS - ABIN1741593 : Feuillard, Jacob, Valensi, Maynadié, Gressin, Chaperot, Arnoulet, Brignole-Baudouin, Drénou, Duchayne, Falkenrodt, Garand, Homolle, Husson, Kuhlein, Le Calvez, Sainty, Sotto, Trimoreau, Béné: Clinical and biologic features of CD4(+)CD56(+) malignancies. in Blood 2002 (PubMed)
    Show all 12 Pubmed References

  5. Human Polyclonal CD68 Primary Antibody for IF (cc), IF (p) - ABIN671406 : Zeng, Zhang, Li, Yang, Chen, Liu: A new method to isolate and culture rat kupffer cells. in PLoS ONE 2013 (PubMed)
    Show all 12 Pubmed References

  6. Mouse (Murine) Polyclonal CD68 Primary Antibody for IHC (fro), IHC (p) - ABIN3044428 : Guo, Liao, Huang, Wang, Huang, Liu: Reversal of adipose tissue loss by probucol in mice with deficiency of both scavenger receptor class B type 1 and LDL receptor on high fat diet. in Biochemical and biophysical research communications 2017 (PubMed)
    Show all 11 Pubmed References

  7. Human Polyclonal CD68 Primary Antibody for IHC (p), WB - ABIN3044053 : Gu, Wu, Yao, Zeng, Shi, Lv, Luo, Song: Intratracheal administration of mitochondrial DNA directly provokes lung inflammation through the TLR9-p38 MAPK pathway. in Free radical biology & medicine 2015 (PubMed)
    Show all 10 Pubmed References

  8. Mouse (Murine) Polyclonal CD68 Primary Antibody for IHC (p), WB - ABIN5518672 : Peng, Liu, Wei, Lv, Wang, Xiong, Wang, Altaf, Wang, He, Wang, Qu: P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation. in International journal of molecular medicine 2015 (PubMed)
    Show all 10 Pubmed References

  9. Mouse (Murine) Polyclonal CD68 Primary Antibody for IHC, ELISA - ABIN1586039 : Wu, Chuang, Yang, Lin: A standardized aqueous extract of Anoectochilus formosanus ameliorated thioacetamide-induced liver fibrosis in mice: the role of Kupffer cells. in Bioscience, biotechnology, and biochemistry 2010 (PubMed)
    Show all 6 Pubmed References

  10. Human Monoclonal CD68 Primary Antibody for IHC (f), FACS - ABIN2749210 : Doussis, Gatter, Mason: CD68 reactivity of non-macrophage derived tumours in cytological specimens. in Journal of clinical pathology 1993 (PubMed)
    Show all 5 Pubmed References

More Antibodies against CD68 Interaction Partners

Mouse (Murine) CD68 Molecule (CD68) interaction partners

  1. Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities.

  2. Myeloid osteoclast precursors do not express CD68.

  3. CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver.

  4. Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age

  5. Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 (show CCR7 Antibodies) / CD68 emigration pathway in macrophages

  6. These findings demonstrate a role for CD68 in the function of osteoclasts.

  7. CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking.

  8. Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques.

  9. Macrosialin does not function as an oxLDL receptor on the cell surface.

  10. Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice.

Human CD68 Molecule (CD68) interaction partners

  1. Most cases of histiocytic sarcoma expressed histiocytic markers CD68 (6 of 7 cases), CD163 (show CD163 Antibodies) (5 of 5 cases), and PU.1 (3 of 4 cases).

  2. Renal expression of CD68 and the chronicity index are associated with progression to chronic kidney disease in patients with proliferative lupus nephritis.

  3. Results indicate that the expression of FoxP3 (show FOXP3 Antibodies) was not significantly associated with survival, and suggest prognostic significance of high CD68 expression in primary central nervous system lymphoma (PCNSL).

  4. Her-2 (show ERBB2 Antibodies) overexpression results in ICA were similar to previous reports, the finding of 28% in HGD (show HGD Antibodies) was unexpected and may have clinical implications. Positive Her-2 (show ERBB2 Antibodies) DISH in 6% of LGD is novel, suggesting a role of Her-2 (show ERBB2 Antibodies) during BE progression

  5. CD68 may play key roles in the pathogenesis of Alzheimer's disease (AD) and its complications may be via induction of inflammation; CD68 may be considered as a risk factor for development of AD and also psychotic symptoms in the patients

  6. hCD68GFP/ApoE (show APOE Antibodies)(-/-) mice provide a new approach to study macrophage accumulation in atherosclerotic plaque progression and to identify cells recruited from adoptively transferred monocytes.

  7. Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities.

  8. The strong CD68 and S100 co-expression in our case did not allow a clear-cut discrimination between the immunophenotype of histiocytic neoplasms and amelanotic melanoma, because of CD68 immunoreactivity occurring in 75% of metastatic malignant melanomas

  9. Using double labeling with Iba-1 (show AIF1 Antibodies) and cd68 could determine the physiological state of microglia in brain contusion based on their morphology and immunoreactivity.

  10. we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1 (show FOLR1 Antibodies), FOLR2 (show FOLR2 Antibodies), CD68 and CD11b (show ITGAM Antibodies) markers

CD68 Antigen Profile

Protein Summary

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Gene names and symbols associated with anti-CD68 Molecule (CD68) Antibodies

  • CD68 molecule (CD68) antibody
  • CD68 antigen (Cd68) antibody
  • Cd68 molecule (Cd68) antibody
  • GP110 antibody
  • LAMP4 antibody
  • SCARD1 antibody

Protein level used designations for anti-CD68 Molecule (CD68) Antibodies

macrosialin , CD68 antigen , macrophage antigen CD68 , scavenger receptor class D, member 1

GENE ID SPECIES
100344094 Oryctolagus cuniculus
12514 Mus musculus
287435 Rattus norvegicus
968 Homo sapiens
504960 Bos taurus
101099002 Felis catus
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