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anti-CD70 Molecule (CD70) Antibodies

The protein encoded by CD70 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. Additionally we are shipping CD70 Proteins (28) and CD70 Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD70 21948 O55237
CD70 970 P32970
CD70 301132  
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Top anti-CD70 Antibodies at

Showing 10 out of 178 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rat Un-conjugated Func, FACS Staining of 4 -day LPS activated BALB/c splenocytes with 0.25 µg of FG... 100 μg Log in to see 5 to 6 Days
Human Mouse PE Func, ICC, IHC (fro), FACS, ELISA   120 Tests Log in to see 8 to 10 Days
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
Mouse Rat Biotin FACS 50 μg Log in to see 10 to 12 Days
Mouse Rat Un-conjugated Func, FACS, IP Surface staining of LPS + anti-mouse CD40 (ABIN282198) stimulated mous... 100 μg Log in to see 5 to 6 Days
Mouse Rat PE ELISA (Capture), WB 200 μg Log in to see 10 to 12 Days
Human Rabbit Un-conjugated WB WB Suggested Anti-CD70 AntibodyTitration: 1.0 µg/mL  Positive Control:... 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: JurKat 12% SDS PAGE CD... 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated Func, ICC, IHC (fro), FACS, ELISA   100 μg Log in to see 8 to 10 Days
Mouse Rat FITC FACS 0.5 mg Log in to see 6 to 8 Days

CD70 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , , ,
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Human , , , ,
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Rat (Rattus) ,

Top referenced anti-CD70 Antibodies

  1. Mouse (Murine) Monoclonal CD70 Primary Antibody for FACS - ABIN2661128 : Akiba, Oshima, Takeda, Atsuta, Nakano, Nakajima, Nohara, Yagita, Okumura: CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 6 references for ABIN2661128

  2. Mouse (Murine) Monoclonal CD70 Primary Antibody for ELISA (Capture), WB - ABIN2663569 : Tesselaar, Gravestein, van Schijndel, Borst, van Lier: Characterization of murine CD70, the ligand of the TNF receptor family member CD27. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
    Show all 6 references for ABIN2663569

  3. Human Monoclonal CD70 Primary Antibody for Func, ICC - ABIN610194 : Baki, Marambaud, Efthimiopoulos, Georgakopoulos, Wen, Cui, Shioi, Koo, Ozawa, Friedrich, Robakis: Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 3 references for ABIN610194

  4. Human Monoclonal CD70 Primary Antibody for Func, ICC - ABIN610197 : Arnold, Seifert, Asadullah, Volk: Crosstalk between keratinocytes and T lymphocytes via Fas/Fas ligand interaction: modulation by cytokines. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 2 references for ABIN610197

  5. Human Polyclonal CD70 Primary Antibody for ELISA, WB - ABIN1451922 : Goodwin, Alderson, Smith, Armitage, VandenBos, Jerzy, Tough, Schoenborn, Davis-Smith, Hennen: Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor. in Cell 1993 (PubMed)

More Antibodies against CD70 Interaction Partners

Mouse (Murine) CD70 Molecule (CD70) interaction partners

  1. Mice lacking CD70 did not accumulate memory T cells and did not develop hypertension.

  2. find that while stimulation of CD27 (show CD27 Antibodies) in isolation drives weak Eomesodermin (show EOMES Antibodies)(hi) T-bet(lo) CD8 (show CD8A Antibodies)(+) T-cell responses to OVA immunization

  3. Data show that although CD70 is required for the activation of the antiviral adaptive response, it has a regulatory role in early cytokine responses to viruses such as MCMV, possibly through maintenance of Treg survival and function.

  4. the ability of CD70 to trigger costimulation is self-regulated when it binds its complementary receptor.

  5. under conditions of constitutive CD70 expression reflecting chronic immune activation, the CD27 (show CD27 Antibodies)/CD70 system inhibits OC differentiation and favors DC differentiation

  6. mTECs and DCs form dedicated niches in the thymic medulla, in which CD27 (show CD27 Antibodies)-CD70 co-stimulation rescues developing Treg cells from apoptosis, subsequent to Foxp3 (show FOXP3 Antibodies) induction by TCR and CD28 (show CD28 Antibodies) signals.

  7. Expression of CD70 by B cells aggravates experimental autoimmune encephalomyelitis by reducing the number of regulatory T cells.

  8. CD70-deficient mice infected with lymphocytic choriomeningitis virus produced only half as many T8 cells. Viral clearance was substantially delayed. CD70-mediated costimulation is not required for secondary or T4 responses.

  9. The CD27 (show CD27 Antibodies) and CD70 costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity.

  10. population of CD27 (show CD27 Antibodies)(-) Th2 cells was significantly reduced by the anti-CD70 mAb treatment

Human CD70 Molecule (CD70) interaction partners

  1. CD70: An emerging target in cancer immunotherapy

  2. Both monomeric and trimeric forms of CD70 were detected in tumour cell membrane fractions, whereas cytoplasmic fractions contained almost exclusively monomeric CD70

  3. CD70 is overexpressed in systemic lupus erythematosus CD4 (show CD4 Antibodies)+ T cells, but expression is not linked to the typical clinical and serological parameters associated with the disease.

  4. CD70-blocking of alphaDC1s from both controls and patients with chronic lymphocytic leukaemia had a negative influence on the production of both IL-12p70 and the Th1 (show TH1L Antibodies) cytokine IFN-gamma (show IFNG Antibodies).

  5. These results highlight the importance of the CD27 (show CD27 Antibodies)-CD70 costimulation pathway for the development of CMV-specific T cell immunity during acute and persistent infection.

  6. CD70 acts as a functional receptor binding to soluble CD27 (show CD27 Antibodies), resulting in lymphoma progression and that immunotherapy using anti-CD70 antibody may be a potential candidate for treatment for NNKTL.

  7. These results indicate that CD27 (show CD27 Antibodies) and CD70 gene polymorphisms may affect the risk of breast cancer and show that some SNPs are associated with breast cancer characteristics in a northern Chinese population.

  8. The mean expression of CD70 was almost twice as high in renal cell carcinoma (show MOK Antibodies) relative to normal kidney tissue

  9. Regulation of Langerhans cell CD70 expression is important in enhancing immunity against cutaneous epithelial pathogens and cancer.

  10. Findings suggest that demethylation of CD70 promoter region contributes to the overexpression of CD70 in CD4 (show CD4 Antibodies)+ T cells and may contribute to autoimmune response in systemic sclerosis (SSc (show CYP11A1 Antibodies)).

CD70 Antigen Profile

Protein Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Gene names and symbols associated with anti-CD70 Molecule (CD70) Antibodies

  • CD70 antigen (Cd70) antibody
  • CD70 molecule (CD70) antibody
  • Cd70 molecule (Cd70) antibody
  • CD27L antibody
  • CD27LG antibody
  • TNFSF7 antibody

Protein level used designations for anti-CD70 Molecule (CD70) Antibodies

CD27 ligand , CD27-L , Ki-24 antigen , tumor necrosis factor (ligand) superfamily, member 7 , tumor necrosis factor ligand superfamily member 7 , CD70 antigen , surface antigen CD70

21948 Mus musculus
970 Homo sapiens
733577 Sus scrofa
301132 Rattus norvegicus
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