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anti-CD74 Antigen (Invariant Polypeptide of Major Histocompatibility Complex, Class II Antigen-Associated) (CD74) Antibodies

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD74 16149 P04441
CD74 25599 P10247
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Top anti-CD74 Antibodies at antibodies-online.com

Showing 3 out of 10 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Rat Rabbit HRP ELISA, WB 100 μg Log in to see 9 to 11 Days
$328.90
Details
Mouse Rabbit Un-conjugated 100 μg Log in to see 9 to 14 Days
$432.73
Details
Rat Rabbit Un-conjugated 100 μg Log in to see 9 to 14 Days
$432.73
Details

CD74 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


, ,
Rat (Rattus)


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More Antibodies against CD74 Interaction Partners

Mouse (Murine) CD74 Antigen (Invariant Polypeptide of Major Histocompatibility Complex, Class II Antigen-Associated) (CD74) interaction partners

  1. Data show that cathepsins S (CatS) regulates CCL2 (show CCL2 Antibodies) chemokine (show CCL1 Antibodies) expression by modulation of CD74 antigen processing.

  2. Suggest that the DQA1*0103/CD74 dimer may result in presentation of unique antigens and susceptibility to develop arthritis.

  3. CD74 plays a critical role in the MIF (show MIF Antibodies) inhibition of osteoclastogenesis.

  4. Genetic deletion of CD74 restored the ability of infected dendritic cells to present a parasite antigen in the context of MHC-II.

  5. SPPL2a (show SPPL2A Antibodies)-mediated processing of CD74 NTF (show TNF Antibodies) is indispensable to maintain appropriate levels of tonic BCR (show BCR Antibodies) signaling to promote B cell maturation (show TNFRSF17 Antibodies).

  6. Results support the hypothesis that neurodegeneration following traumatic brain injury is dependent upon antigen processing and presentation that requires CD74

  7. Methylglyoxal induced gene expression of CD74 in the in the diabetic retina.

  8. In TPA (show PLAT Antibodies)-induced skin inflammation, MIF (show MIF Antibodies) is released from damaged keratinocytes and then triggers the chemotaxis of CD74(+)CXCR2 (show CXCR2 Antibodies)(+) NKT (show CTSL1 Antibodies) cells for IFN-gamma (show IFNG Antibodies) production.

  9. MIF (show MIF Antibodies) promotes the migration of B cells through a ZAP-70 (show ZAP70 Antibodies)-dependent pathway mediated by cooperative engagement of CXCR4 (show CXCR4 Antibodies) and CD74.

  10. These results demonstrate natural antagonist activity of DRalpha1 for macrophage migration inhibitory factor (show MIF Antibodies)

CD74 Antigen Profile

Protein Summary

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

Gene names and symbols associated with CD74

  • CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Cd74) antibody
  • Cd74 molecule, major histocompatibility complex, class II invariant chain (Cd74) antibody
  • CLIP antibody
  • DHLAG antibody
  • HLADG antibody
  • Ia-GAMMA antibody
  • Ii antibody
  • INVG34 antibody

Protein level used designations for CD74

H-2 class II histocompatibility antigen gamma chain , HLA-DR-GAMMA , Ia-associated invariant chain , MHC class II-associated invariant chain , class II-associated invariant chain peptide , dinucleotide microsatellite , histocompatibility: class II antigens, gamma chain of , ia antigen-associated invariant chain , invariant polypeptide of major histocompatibility complex, class II antigen-associated , ii

GENE ID SPECIES
16149 Mus musculus
25599 Rattus norvegicus
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