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The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Additionally we are shipping CD79a Molecule, Immunoglobulin-Associated alpha Antibodies (536) and CD79a Molecule, Immunoglobulin-Associated alpha Proteins (12) and many more products for this protein.
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BCR (show BCR ELISA Kits) activation is accompanied by asymmetric conformational changes, possibly promoting the binding of Igalpha and Igbeta to differently localized signaling complexes
CD79a myeloid cells showed enhanced ability to promote primary tumor growth and metastasis.
Data indicate that in the absence of DGKzeta (show DGKZ ELISA Kits), the threshold for B cell antigen receptor (BCR (show BCR ELISA Kits)) signaling, measured as activation of the Ras-extracellular signal-regulated kinase (ERK (show EPHB2 ELISA Kits)) pathway, was markedly reduced in mature follicular B cells.
Data show that the B cell antigen receptor (BCR (show BCR ELISA Kits)) and Igalpha may be required for B cell survival because they function as adaptor proteins in a BAFFR (show TNFRSF13C ELISA Kits) signaling pathway leading to activation of Syk (show SYK ELISA Kits), indicating crosstalk between the two receptors.
The mouse B cell-specific mb-1 (show PSMB5 ELISA Kits) gene encodes an immunoreceptor tyrosine-based activation motif (ITAM) protein that may be evolutionarily conserved in diverse species by purifying selection.
endocytosed BCR (show BCR ELISA Kits) sequentially regulates MAPK (show MAPK1 ELISA Kits) and Akt (show AKT1 ELISA Kits) signaling pathways from intracellular compartments
Arginine 198 in the tail of the Igalpha subunit of the BCR (show BCR ELISA Kits) is methylated by the protein arginine methyltransferase 1 (show PRMT1 ELISA Kits). Methylation negatively regulates the calcium and PI-3 (show PI3 ELISA Kits) kinase pathways of the BCR (show BCR ELISA Kits), promoting signals leading to B (show TDO2 ELISA Kits) cell differentiation.
The direct recruitment of BLNK (show BLNK ELISA Kits) to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways
IgA deficiency in lymphotoxin-deficient (LT(-/-)) mice could be fully reversed by reconstitution with LT-expressing bone marrow, despite the absence of both LNs and PPs.
The VHDJH recombination process at the IgH locus and the survival of pro-B cells that carry these rearrangements do not depend on the expression of Ig-alpha molecules.
The incidence of MYD88 (show MYD88 ELISA Kits) and CD79B (show CD79B ELISA Kits) mutations in patients with CD5 (show CD5 ELISA Kits)(+) DLBCL is lower than that in patients with DLBCL-SS, suggesting that CD5 (show CD5 ELISA Kits)(+) DLBCL is not the same disease as DLBCL-SS in terms of gene mutation status.
Data show that Bruton tyrosine kinase (BTK (show BTK ELISA Kits))inhibitor Ibrutinib augments MALT lymphoma associated translocation (show MALT1 ELISA Kits) protein (MALT1 (show MALT1 ELISA Kits)) inhibition by S-Mepazine in CD79 antigen mutant activated B cell-subtype (ABC (show ABCB6 ELISA Kits)) of diffuse large B cell lymphoma (DLBCL).
Phosphorylation of CD79a causes a decrease in helical propensity in the C-terminal region, for CD79b (show CD79B ELISA Kits), the opposite was observed and phosphorylation resulted in an increase of helical propensity in the C-terminal part.
High intensity of caries is associated with increased levels of some salivary components - sIgA, histatin-5 (show HTN3 ELISA Kits) and lactoperoxidase (show LPO ELISA Kits).
CD79a plays a functional role in the tumor promoting effects of myeloid cells, and may represent a novel target for cancer therapy.
STN (show EEF1A2 ELISA Kits) produced significant antitumor effects in a mouse xenograft model of CD79A/B-mutated DLBCL.
CD79a may be helpful marker in the differential diagnosis of classical Hodgkin's lymphoma and primary mediastinal B-cell lymphoma
Unlike the B29 (show CD79B ELISA Kits) octamer motif, the mb-1 (show PSMB5 ELISA Kits) octamer motif does not have the essential sequence required for OBF-1/Bob1 (show POU2AF1 ELISA Kits) interaction, therefore its promoter is not transactivated by OBF-1/Bob1 (show POU2AF1 ELISA Kits).
B cell-restricted mb-1 (show PSMB5 ELISA Kits) gene: expression, function, and lineage infidelity. Review.
Results indicate that PAX5 (show PAX5 ELISA Kits) is a more specific marker than CD79a for B-cell ALL diagnosis.
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
CD79a molecule, immunoglobulin-associated alpha
, B-cell antigen receptor complex-associated protein alpha chain
, Ig alpha
, MB-1 membrane glycoprotein
, immunoglobulin-associated alpha
, membrane-bound immunoglobulin-associated protein
, surface IgM-associated protein
, CD79a antigen (immunoglobulin-associated alpha)
, CD79-alpha protein
, CD79A antigen (immunoglobulin-associated alpha)
, B-cell antigen receptor complex-associated protein alpha-chain