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anti-CD8b Molecule (CD8B) Antibodies

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. Additionally we are shipping CD8B Proteins (19) and CD8B Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD8B 12526 P10300
CD8B 926 P10966
CD8B 24931 P05541
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Top anti-CD8B Antibodies at antibodies-online.com

Showing 10 out of 309 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-CD8B Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-CD8B  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of anti-CD8B1 Pab (ABIN388214) in K562 cell line lysates (35 µg/lane). CD8B1(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Flow cytometric analysis of jurkat cells using CD8B Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Mouse Un-conjugated CyTox Cytotoxic index 0.5 mL Log in to see 6 to 8 Days
$632.50
Details
Mouse Rat Biotin FACS Flow Cytometry - Cell Source: Spleen - Percentage of cells stained above control: 9.2% 0.3 mg Log in to see 6 to 8 Days
$687.50
Details
Rat Mouse Biotin FACS   0.1 mg Log in to see 6 to 8 Days
$308.00
Details
Rat Mouse PE FACS   0.2 mg Log in to see 6 to 8 Days
$731.50
Details
Rat Mouse FITC FACS   0.5 mg Log in to see 6 to 8 Days
$753.50
Details
Rat Mouse Un-conjugated FACS, IP, WB   0.1 mg Log in to see 6 to 8 Days
$198.00
Details
Human Mouse Un-conjugated FACS, IP, WB   0.2 mg Log in to see 6 to 8 Days
$489.50
Details

CD8B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CD8B Antibodies

  1. Mouse (Murine) Monoclonal CD8B Primary Antibody for CyTox - ABIN114180 : Raulet, Gottlieb, Bevan: Fractionation of lymphocyte populations with monoclonal antibodies specific for LYT-2.2 and LYT-3.1. in Journal of immunology (Baltimore, Md. : 1950) 1980 (PubMed)
    Show all 4 references for ABIN114180

  2. Human Polyclonal CD8B Primary Antibody for EIA, WB - ABIN356930 : Nakayama, Kawachi, Tokito, Minami, Yamamoto, Imai, Gachelin, Nakauchi: Recent duplication of the two human CD8 beta-chain genes. in Journal of immunology (Baltimore, Md. : 1950) 1992 (PubMed)
    Show all 3 references for ABIN356930

  3. Rat (Rattus) Monoclonal CD8B Primary Antibody for FACS - ABIN951410 : Torres-Nagel, Kraus, Brown, Tiefenthaler, Mitnacht, Williams, Hünig: Differential thymus dependence of rat CD8 isoform expression. in European journal of immunology 1992 (PubMed)
    Show all 2 references for ABIN951410

  4. Rat (Rattus) Monoclonal CD8B Primary Antibody for FACS - ABIN951407 : Elflein, Rodriguez-Palmero, Kerkau, Hünig: Rapid recovery from T lymphopenia by CD28 superagonist therapy. in Blood 2003 (PubMed)
    Show all 2 references for ABIN951407

  5. Chicken Monoclonal CD8B Primary Antibody for FACS - ABIN371368 : Tregaskes, Kong, Paramithiotis, Chen, Ratcliffe, Davison, Young et al.: Identification and analysis of the expression of CD8 alpha beta and CD8 alpha alpha isoforms in chickens reveals a major TCR-gamma delta CD8 alpha beta subset of intestinal intraepithelial ... in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
    Show all 2 references for ABIN371368

  6. Mouse (Murine) Monoclonal CD8B Primary Antibody for FACS - ABIN114182 : Ledbetter, Herzenberg: Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. in Immunological reviews 1980 (PubMed)

  7. Dog (Canine) Polyclonal CD8B Primary Antibody for WB - ABIN2775290 : Moody, North, Reinhold, Van Dyken, Rogers, Panico, Dell, Morris, Marth, Reinherz: Sialic acid capping of CD8beta core 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction. in The Journal of biological chemistry 2003 (PubMed)

More Antibodies against CD8B Interaction Partners

Mouse (Murine) CD8b Molecule (CD8B) interaction partners

  1. Lck (show LCK Antibodies)-CD8 (show CD8A Antibodies) interaction is required for initial CD8 (show CD8A Antibodies) recruitment.

  2. Comparing the sequences of mouse, human, rat and dog Cd8a and Cd8b1 gene loci identified 10 evolutionarily conserved regions (ECR). 6 ECRs overlapped with previously identified Cd8 enhancers. ECR-4 recruits transcription factors to the Cd8ab gene complex.

  3. CREMalpha orchestrates epigenetic remodeling of the CD8A (show CD8A Antibodies),B through the recruitment of DNA methyltransferase (show DNMT1 Antibodies) (DNMT (show DNMT1 Antibodies)) 3a and histone methyltransferase G9a (show EHMT2 Antibodies).

  4. We propose that ADP-ribosylation of CD8 (show CD8A Antibodies)-beta can regulate the coreceptor function of CD8 (show CD8A Antibodies) in the presence of elevated levels of extracellular NAD(+) .

  5. sialylation in a discrete segment of the CD8beta stalk by ST3Gal-1 sialyltransferase creates a molecular developmental switch that affects ligand binding

  6. Data demonstrate that major histocompatibility complex-I-signaled thymocytes appear as CD4 (show CD4 Antibodies)+8lo cells because of transient down-regulation of CD8 (show CD8A Antibodies) gene expression, not because of changes in CD8 (show CD8A Antibodies) surface protein expression or distribution.

  7. The stalk region of CD8 (show CD8A Antibodies) beta is capable of fine-tuning the coreceptor function of CD8 (show CD8A Antibodies) proteins as a coreceptor, possibly due to its distinct protein structure, smaller physical size and the unique glycan adducts associated with this region.

  8. results demonstrate epigenetic control of the Cd8 (show CD8A Antibodies) loci and identify MAZR (show ZNF278 Antibodies) as an important regulator of Cd8 (show CD8A Antibodies) expression

  9. The crystal structure of the CD8alphabeta immunoglobulin-like ectodomains were determined in complex with mAb YTS156.7 Fab (show FANCB Antibodies) at 2.7 A resolution, was elucidated.

  10. The stalk region of CD8beta influences the ability of CD8 (show CD8A Antibodies) to bind class I major histocompatibility complexes and is therefore critical for the correct functioning of CD8alphabeta heterodimers.

Human CD8b Molecule (CD8B) interaction partners

  1. CREMalpha orchestrates epigenetic remodeling of the CD8A (show CD8A Antibodies),B through the recruitment of DNA methyltransferase (show DNMT1 Antibodies) (DNMT (show DNMT1 Antibodies)) 3a and histone methyltransferase G9a (show EHMT2 Antibodies).

  2. transcription factor cAMP-responsive element modulator (show CREM Antibodies) alpha (CREMalpha), which is expressed at increased levels in T cells from systemic lupus erythematosus patients, contributes to transcriptional silencing of CD8A (show CD8A Antibodies) and CD8B.

  3. A clustering of DNase (show DNASE2 Antibodies) hypersensitivity sites and matrix attachment regions capable of binding SATB1 (show SATB1 Antibodies) and GATA-3 (show GATA3 Antibodies), colocalized at the 3' end of the CD8B gene, suggests that this region is an epigenetic regulator of CD8 (show CD8A Antibodies) expression.

  4. RT-PCR, and related methodologies are not useful substitutes for assessment of CD4 (show CD4 Antibodies) and CD8 (show CD8A Antibodies) cell numbers in HIV-infected persons.

  5. study demonstrated differential mRNA expression patterns of CD8beta splice variants in thymocytes and in resting, memory, and activated primary CD8 (show CD8A Antibodies)(+) T cells

  6. Data show that CD8 (show CD8A Antibodies)+LAP+ cells produce IFN-gamma (show IFNG Antibodies), and these cells suppress EAE that is dependent on both TGF-beta (show TGFB1 Antibodies) and IFN-gamma (show IFNG Antibodies).

CD8B Antigen Profile

Protein Summary

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Gene names and symbols associated with anti-CD8b Molecule (CD8B) Antibodies

  • CD8b molecule (Cd8b) antibody
  • CD8b molecule (CD8B) antibody
  • CD8 antigen, beta chain 1 (Cd8b1) antibody
  • Cd8b antibody
  • Cd8b1 antibody
  • LEU2 antibody
  • Ly-3 antibody
  • Ly-C antibody
  • LY3 antibody
  • Lyt-3 antibody
  • LYT3 antibody
  • P37 antibody

Protein level used designations for anti-CD8b Molecule (CD8B) Antibodies

CD8 beta , CD8 beta-2 , T-cell surface glycoprotein CD8 beta chain , CD8 antigen beta polypeptide , T-cell membrane glycoprotein Ly-3 , T-cell surface glycoprotein Lyt-3 , lymphocyte antigen 3 , CD8 antigen, beta polypeptide 1 (p37) , T lymphocyte surface glycoprotein beta chain , CD8 antigen 37 kDa chain , CD8 antigen beta-chain , CD8 antigen, beta chain , CD8 antigen, beta-chain , OX-8 membrane antigen , CD8 beta chain , CD8 antigen, beta polypeptide , CD8b antigen

GENE ID SPECIES
100379572 Cavia porcellus
396636 Sus scrofa
12526 Mus musculus
926 Homo sapiens
24931 Rattus norvegicus
396175 Gallus gallus
493948 Felis catus
508633 Bos taurus
483076 Canis lupus familiaris
101103712 Ovis aries
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