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CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) Proteins (CDC14A)

The protein encoded by CDC14A is a member of the dual specificity protein tyrosine phosphatase family. Additionally we are shipping CDC14A Antibodies (83) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CDC14A 229776 Q6GQT0
CDC14A 8556 Q9UNH5
Rat CDC14A CDC14A 310806  
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Top CDC14A Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

CDC14A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) (CDC14A) Interaction Partners

Xenopus laevis CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) (CDC14A) interaction partners

  1. We demonstrate that XCdc14A upregulation prevents targeting of exocyst and SNARE (show NAPA Proteins) complexes to the midbody, both essential for abscission to occur.

Mouse (Murine) CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) (CDC14A) interaction partners

  1. Cdc14B (show CDC14B Proteins) knockout (Cdc14B (show CDC14B Proteins)(-/-)) mouse embryonic fibroblasts showed defects in repairing ionizing radiation-induced DNA double-strand breaks, which occurred only at late passages when Cdc14A levels were low.

  2. CDC14A regulates oocyte maturation and functions to promote the meiosis I-to-meiosis II transition as its homolog does in budding yeast.

Human CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) (CDC14A) interaction partners

  1. These findings indicated that ZIPK (show DAPK3 Proteins) may also be involved in the regulation of the cell cycle in human cells, by interacting with HsCdc14A.

  2. These data support the hypothesis that Cdc14A counteracts Cdk1 (show CDK1 Proteins)-cyclin B1 (show CCNB1 Proteins) activity through Wee1 (show WEE1 Proteins) dephosphorylation.

  3. CDC (show CDK1 Proteins) (cell division cycle) 14A/B phosphatases associate with KIBRA (show WWC1 Proteins), and CDK1 (show CDK1 Proteins)-non-phosphorylatable KIBRA (show WWC1 Proteins) has greatly reduced interaction with CDC14B (show CDC14B Proteins).

  4. Cdc14 phosphatase plays a role in cell cycle control in higher eukaryotes.

  5. Cdc14A phosphatase prevents premature activation of Cdk1 (show CDK1 Proteins) regulating Cdc25A (show CDC25A Proteins) and Cdc25B (show CDC25B Proteins) at the entry into mitosis.

  6. human HCT116, and human telomerase reverse transcription-immortalized retinal pigment epithelial cells deleted for Cdc14A are DNA damage checkpoint proficient and arrest efficiently in G2 in response to irradiation.

  7. human Cdc14A phosphatase disrupts centrosome separation

  8. hCdc14A and hCdc14B have functional homology to S. pombe Cdc25 and flp1

  9. analysis of iron-responsive elements in the 3'UTR of CDC14a protein

  10. hCdc14A is differentially expressed in human cancer cells and can interact with both p53 (show TP53 Proteins) and the Cdk1 (show CDK1 Proteins)/cyclin B complex; it may play a role in carcinogenesis

CDC14A Protein Profile

Protein Summary

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.

Gene names and symbols associated with CDC14A

  • Dual specificity protein phosphatase CDC14A (TVAG_168700)
  • Dual specificity protein phosphatase CDC14A (TVAG_479730)
  • Dual specificity protein phosphatase CDC14A (TVAG_362610)
  • Dual specificity protein phosphatase CDC14A (TVAG_490830)
  • Dual specificity protein phosphatase CDC14A (GL50803_9270)
  • dual specificity protein phosphatase CDC14A (CMU_014610)
  • cell division cycle 14A (cdc14a)
  • CDC14 cell division cycle 14 homolog A (S. cerevisiae) (CDC14A)
  • CDC14 cell division cycle 14A (Cdc14a)
  • cell division cycle 14A (CDC14A)
  • cell division cycle 14A (Cdc14a)
  • A830059A17Rik protein
  • cdc14 protein
  • CDC14a1 protein
  • CDC14A2 protein
  • hCDC14 protein
  • xcdc14a protein

Protein level used designations for CDC14A

Dual specificity protein phosphatase CDC14A , dual specificity protein phosphatase CDC14A , CDC14 cell division cycle 14 homolog A , cell division cycle 14 homolog A , CDC14 homolog A , CDC14 cell division cycle 14 homolog A (S. cerevisiae) , dual specificity protein phosphatase CDC14A-like , CDC10 (cell division cycle 10, S. cerevisiae, homolog)

GENE ID SPECIES
4753421 Trichomonas vaginalis G3
4756602 Trichomonas vaginalis G3
4769839 Trichomonas vaginalis G3
4771944 Trichomonas vaginalis G3
5701321 Giardia lamblia ATCC 50803
6996284 Cryptosporidium muris RN66
403393 Xenopus laevis
424466 Gallus gallus
457058 Pan troglodytes
100346294 Oryctolagus cuniculus
100477147 Ailuropoda melanoleuca
100490252 Xenopus (Silurana) tropicalis
479926 Canis lupus familiaris
229776 Mus musculus
8556 Homo sapiens
614777 Bos taurus
310806 Rattus norvegicus
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