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CDC28 Protein Kinase Regulatory Subunit 1B (CKS1B) ELISA Kits

CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. Additionally we are shipping CKS1 Antibodies (38) and CKS1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat CKS1B CKS1B 499655  
Anti-Mouse CKS1B CKS1B 54124 P61025
Anti-Human CKS1B CKS1B 1163 P61024
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More ELISA Kits for CKS1 Interaction Partners

Mouse (Murine) CDC28 Protein Kinase Regulatory Subunit 1B (CKS1B) interaction partners

  1. Cks1 is critical for Bcr-Abl (show ABL1 ELISA Kits)-induced cytokine-independent clonogenic activity.

  2. show that CKS2 counteracts CKS1 and stabilizes p27 (show CDKN1B ELISA Kits)

  3. Cks1 is overexpressed in various B cell malignancies, is required for tumor cell proliferation but is not sufficient to induce hematopoietic malignancies.

  4. establish p27(Kip1 (show CDKN1B ELISA Kits))-independent functions of Cks1 in regulating the G(1)-S transition

  5. Collectively, these findings suggest that Cks1 targets, in addition to p27(Kip1 (show CDKN1B ELISA Kits)), are critical for Myc (show MYC ELISA Kits)-driven proliferation and tumorigenesis.

  6. FGFR (show FGFR2 ELISA Kits) kinase regulates the cell cycle through phosphorylation-dependent release of Cks1 from FGFR substrate 2 (show FRS2 ELISA Kits)

  7. Elevated expression of Cks1 may contribute to prostate tumorigenesis by promoting proliferation, anchorage-independent growth and migration of the cells, and elevated expression of Cks2 by protecting cells from undergoing programmed cell death.

  8. Data show that cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells.

Human CDC28 Protein Kinase Regulatory Subunit 1B (CKS1B) interaction partners

  1. Results show that Cks1 and Cks2 promoted proliferation and prevented apoptosis of hepatocellular carcinoma HepG2 cells.

  2. Specifically, CKS1B and MAP2K5 (show MAP2K5 ELISA Kits) significantly inhibited hepatitis C viral RNA replication. PACSIN1 (show PACSIN1 ELISA Kits), by contrast, inhibited hepatitis C virus infection by decreasing the level of viral protein p7.

  3. Regulation of Cks1 protein stability is crucially dependent on specific tyrosine and lysine residues which are potential sites for post-translational modifications.

  4. We conclude that perturbing the Hsp90 pathway could provide a useful therapeutic strategy in tumors driven by Cks1 overexpression

  5. Our results suggest a role for CKS1B in the multiple step process of progression of MGUS to MM and show that CKS1B copy gain has a more significant prognostic value than its overexpression.

  6. EGF (show EGF ELISA Kits) upregulates the mRNA and protein levels of Skp2/Cks1 and p27(kip1 (show CDKN1B ELISA Kits)) via the PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway and direct binding of E2F1 transcription factor (show E2F1 ELISA Kits) with the Skp2 promoter in extrahepatic cholangiocarcinoma cells.

  7. CKS1 mRNA and protein expression were increased in esophageal carcinoma. Overexpression of CKS1 was associated with higher grad, regional lymph node invasion, and neoplastic embolus. CKS1 was negatively associated with the p27(kip1 (show CDKN1B ELISA Kits)) level in the tumor.

  8. We demonstrated that high expression of CKS1B immunostaining can be one potent prognostic factor for disease-specific survival, metastasis-free survival, and local recurrence-free survival in patients with nasopharyngeal carcinoma.

  9. Anaplastic multiple myeloma was associated with significantly higher prevalence of CKS1B amplification than non-anaplastic multiple myeloma.

  10. CKS1B analysis predicts 1q21 amplification and adverse outcome for risk stratification of patients with multiple myeloma.

CKS1 (CKS1B) Antigen Profile

Antigen Summary

CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.

Gene names and symbols associated with CKS1B

  • CDC28 protein kinase regulatory subunit 1B (Cks1b) antibody
  • CDC28 protein kinase regulatory subunit 1B (CKS1B) antibody
  • CDC28 protein kinase regulatory subunit 1B (cks1b-a) antibody
  • CDC28 protein kinase regulatory subunit 1B (cks1b-b) antibody
  • CDC28 protein kinase regulatory subunit 1B (cks1b) antibody
  • CDC28 protein kinase 1b (Cks1b) antibody
  • cyclin-dependent kinases regulatory subunit 1 (CKS1) antibody
  • 2410005G18Rik antibody
  • 2610005D03Rik antibody
  • AA407784 antibody
  • CATALYTIC SUBUNIT OF CYCLIN-DEPENDENT KINASE antibody
  • CKS-1 antibody
  • CKS1 antibody
  • CKS1AT antibody
  • cks1b antibody
  • cks1ba antibody
  • cks1bb antibody
  • ckshs1 antibody
  • cyclin-dependent kinase-subunit 1 antibody
  • MGC131304 antibody
  • P10CKS1AT antibody
  • PNAS-16 antibody
  • PNAS-18 antibody
  • RGD1561797 antibody
  • Sid 1334 antibody
  • sid1334 antibody
  • T1E2.12 antibody
  • T1E2_12 antibody
  • zgc:101026 antibody

Protein level used designations for CKS1B

cyclin-dependent kinases regulatory subunit 1 , CDC28 protein kinase regulatory subunit 1B , CDC28 protein kinase regulatory subunit 1B-A , CDC28 protein kinase regulatory subunit 1B-B , CDC28 protein kinase 1B , CKS-1 , cyclin-dependent kinase regulatory subunit 1 , sid 1334 , CDC2-associated protein CKS1 , CDC28 protein kinase 1 , NB4 apoptosis/differentiation related protein , PNAS-143 , cell division control protein CKS1 , CDC28 protein kinase regulatory subunit 1

GENE ID SPECIES
499655 Rattus norvegicus
612237 Canis lupus familiaris
734841 Xenopus laevis
741634 Pan troglodytes
100049098 Xenopus laevis
100101691 Xenopus (Silurana) tropicalis
100134845 Gallus gallus
100134846 Taeniopygia guttata
445199 Danio rerio
54124 Mus musculus
1163 Homo sapiens
615827 Bos taurus
817340 Arabidopsis thaliana
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