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Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Additionally we are shipping CDC42 Small Effector 1 Kits (4) and CDC42 Small Effector 1 Antibodies (3) and many more products for this protein.
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Overexpression studies of the related SPEC1 showed that it also was recruited to the activated TCR. Mutational analysis revealed that localization of SPEC1 to the TCR required two N-terminal cysteine residues
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages (By similarity).
, CDC42 small effector protein 1
, CDC42-binding protein SCIP1
, signaling molecule SPEC1 beta
, small effector of CDC42 protein 1
, small protein effector 1 of Cdc42
, hypothetical protein