CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) ELISA Kits

The protein encoded by CDKAL1 is a member of the methylthiotransferase family. Additionally we are shipping CDKAL1 Antibodies (42) and CDKAL1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CDKAL1 54901 Q5VV42
CDKAL1 68916 Q91WE6
Anti-Rat CDKAL1 CDKAL1 361243  
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More ELISA Kits for CDKAL1 Interaction Partners

Human CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) interaction partners

  1. family-based GWAS of imputed SNPs revealed novel genomic variants in (or near) PTPRG (show PTPRG ELISA Kits), OSBPL6 (show OSBPL6 ELISA Kits), and PDCL3 (show PDCL3 ELISA Kits) that influence risk for Alzheimer's Disease. rs7609954 in the gene PTPRG (show PTPRG ELISA Kits), rs1347297 in the gene OSBPL6 (show OSBPL6 ELISA Kits), and rs1513625 near PDCL3 (show PDCL3 ELISA Kits). In addition, rs72953347 in OSBPL6 (show OSBPL6 ELISA Kits) and two SNPs in the gene CDKAL1 showed marginally significant association with LOAD (rs10456232, P-value=4.76 x 10-7; rs62400067, P-value=3.54 x 10-7).

  2. The multivariate logistic regression analysis with reference to both alleles and genotypes of CDKAL1 SNPs showed significant association, suggesting an important role for this gene in the T2DM pathophysiology. INTERPRETATION & CONCLUSIONS: A significant association was seen of all the three SNPs of CDKAL1 and CDKN2A/B genes with T2DM but none of the two SNPs of HHEX (show HHEX ELISA Kits).

  3. Study provides evidence that SNPs of JMJD1C and KCNQ1 (show KCNQ1 ELISA Kits) are prospectively associated with the risk of type 2 diabetes (T2D) in Korean population. Additionally, CDKAL1 may not be associated with T2D onset over the age of 40.

  4. Our results suggest that rs6908425 in CDKAL1 is associated with the risk of developing SAPHO in Han Chinese populations. People who carry the risk allele T of rs6908425 might be more prone to developing SAPHO syndrome.

  5. We investigated the association between 8 single-nucleotide polymorphisms (SNPs) at 3 genetic loci (CDKAL1, CDKN2A/2B and FTO (show FTO ELISA Kits)) with type 2 diabetes (T2D) in a Uyghur population

  6. our data suggested that CDKAL1 gene variants have a significant effect on the response to anti-TNF (show TNF ELISA Kits) therapies among Psoriasis patients

  7. Risk alleles for 6 loci increased glucose levels from birth to 5 years of age (ADCY5 (show ADCY5 ELISA Kits), ADRA2A (show ADRA2A ELISA Kits), CDKAL1, CDKN2A/B, GRB10 (show GRB10 ELISA Kits), and TCF7L2 (show TCF7L2 ELISA Kits)

  8. rs10946398 associated with markers of impaired insulin (show INS ELISA Kits) secretion

  9. We observed novel selection signals in CDKAL1 and NEGR1 (show NEGR1 ELISA Kits), well-known diabetes and obesity susceptibility genes

  10. study found SNP rs7754840 in CDKAL1, rs864745 in JAZF1 (show JAZF1 ELISA Kits), and rs35767 in IGF1 (show IGF1 ELISA Kits) might serve as potential susceptibility loci for type 2 diabetes in the Uyghur population

Mouse (Murine) CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1) interaction partners

  1. CDKAL1 may affect such compensatory mechanisms regulating glucose homeostasis through interaction with diet

  2. Knockout mice with pancreatic beta-cell-specific lack of cdkal1 show pancreatic islet hypertrophy and impaired blood glucose control.

  3. Data show that Cdkal1 is a mammalian methylthiotransferase that biosynthesizes 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A) in tRNA(Lys (show LYZ ELISA Kits))(UUU) and that it is required for the accurate translation of AAA (show AAAS ELISA Kits) and AAG codons.

  4. CDKAL1 controls first-phase insulin (show INS ELISA Kits) exocytosis in beta cells by facilitating ATP generation, K(ATP) channel responsiveness and the subsequent activity of Ca(2 (show CA2 ELISA Kits)+) channels through pathways other than CDK5 (show CDK5 ELISA Kits)-mediated regulation

CDKAL1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes.

Gene names and symbols associated with CDKAL1

  • CDK5 regulatory subunit associated protein 1 like 1 (CDKAL1) antibody
  • CDK5 regulatory subunit associated protein 1-like 1 (cdkal1) antibody
  • CDK5 regulatory subunit associated protein 1-like 1 S homeolog (cdkal1.S) antibody
  • threonylcarbamoyladenosine tRNA methylthiotransferase (LOC587594) antibody
  • CDK5 regulatory subunit associated protein 1-like 1 (Cdkal1) antibody
  • 1190005B03Rik antibody
  • 6620401C13Rik antibody
  • MGC76088 antibody
  • MGC78779 antibody
  • zgc:65864 antibody

Protein level used designations for CDKAL1

CDK5 regulatory subunit-associated protein 1-like 1 , tRNA-t(6)A37 methylthiotransferase , threonylcarbamoyladenosine tRNA methylthiotransferase , CDK5 regulatory subunit associated protein 1-like 1

100052309 Equus caballus
393600 Danio rerio
394802 Xenopus (Silurana) tropicalis
420823 Gallus gallus
432014 Xenopus laevis
530159 Bos taurus
587594 Strongylocentrotus purpuratus
747778 Pan troglodytes
100024680 Monodelphis domestica
54901 Homo sapiens
488240 Canis lupus familiaris
68916 Mus musculus
361243 Rattus norvegicus
100512355 Sus scrofa
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