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CMTM1 belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. Additionally we are shipping CKLF-Like MARVEL Transmembrane Domain Containing 1 Antibodies (28) and and many more products for this protein.
CMTM1 and 3 are priority targets in glioblastomas. First insights into signalling of these two genes that might be conveyed by growth factor receptor (show RYK ELISA Kits), Src (show SRC ELISA Kits) family kinase and WNT (show WNT2 ELISA Kits) activation was presented.
Study shows that CMTM1_v17 is highly expressed in human testis and many human tumor tissues and cell lines and seems to enhance cell proliferation and resistance to tumor necrosis factor-alpha (TNF-alpha (show TNF ELISA Kits))-induced apoptosis in MDA-MB-231 breast cancer cells.
Bioinformatics based on CKLF2 (show CKLF ELISA Kits) cDNA and protein sequences in combination with experimental validation identified CKLFSF1-8 gene clusters, between the SCY (show CELSR1 ELISA Kits) and the TM4SF (show TSPAN1 ELISA Kits) gene families. The 8 family members were cloned and characterized.
novel evidence that the final intron/exon region of the CKLFSF1 gene contains a novel eukaryotic promoter capable of directing expression of the downstream gene, CKLFSF2 (show CMTM2 ELISA Kits)
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).
CKLF-like MARVEL transmembrane domain-containing protein 1
, chemokine-like factor super family 1
, chemokine-like factor superfamily 1
, chemokine-like factor superfamily member 1
, chemokine-like factor-like protein CKLFH1