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CMTM7 belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. Additionally we are shipping CMTM7 Antibodies (38) and CMTM7 Kits (20) and many more products for this protein.
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Findings indicate the role of CMTM7 protein in the regulation of epidermal growth factor receptor (EGFR (show EGFR Proteins))-AKT (show AKT1 Proteins) proto-oncogene (show RAB1A Proteins) protein signaling in tumor cells, and as a molecule related to Rab5 (show RAB5A Proteins) GTP-binding protein activation.
Loss of CMTM7 by promoter CpG methylation is associated with neoplasms.
The CMTM7 expression may be related to survival of patients with non-smallcell lung cancer and a unique prognostic factor. CMTM7 may play an important role in NSCLC development.
CMTM7 functions to link sIgM and BLNK (show BLNK Proteins) in the plasma membrane.
Bioinformatics based on CKLF2 cDNA and protein sequences in combination with experimental validation identified CKLFSF1 (show CMTM1 Proteins)-8 gene clusters, between the SCY and the TM4SF (show TSPAN1 Proteins) gene families. The 8 family members were cloned and characterized.
The reduction of B-1a cells in Cmtm7(flox/) mice was associated with reduced BCR (show BCR Proteins) expression.
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified.
CKLF-like MARVEL transmembrane domain-containing protein 7
, chemokine-like factor super family 7
, chemokine-like factor super family member 7 variant 2
, chemokine-like factor superfamily 7
, chemokine-like factor superfamily member 7
, CKLF-like MARVEL transmembrane domain containing 7 L homeolog