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CRTC3 is a member of the CREB regulated transcription coactivator gene family. Additionally we are shipping CRTC3 Kits (3) and CRTC3 Proteins (3) and many more products for this protein.
Showing 10 out of 29 products:
Human Monoclonal CRTC3 Primary Antibody for ICC, IHC - ABIN969068
Fehr, Röser, Heidorn, Hallas, Löning, Bullerdiek: A new type of MAML2 fusion in mucoepidermoid carcinoma. in Genes, chromosomes & cancer 2008
Show all 2 references for ABIN969068
Human Monoclonal CRTC3 Primary Antibody for EIA, IF - ABIN1106841
Nakayama, Miyabe, Okabe, Sakuma, Ijichi, Hasegawa, Nagatsuka, Shimozato, Inagaki: Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009
Show all 2 references for ABIN1106841
beta-agonists or catecholamines released during intense exercise induce Creb (show CREB1 Antibodies)-mediated transcriptional programs through activation of its obligate coactivators Crtc2 (show CRTC2 Antibodies) and Crtc3.
CRTC3 plays a selective role in mitochondrial biogenesis in response to rotenone
the cAMP response element binding (CREB) coactivator Crtc3 promotes obesity by attenuating beta-adrenergic receptor signalling in adipose tissue
The CRTC3 polymorphism rs3862434 is associated with the plasma level of total cholesterol, and rs11635252 is associated with the risks of overweight and hypertriglyceridemia in a Chinese Han population.
Metaplastic Warthin tumor and metaplastic pleomorphic adenoma of salivary glands did not harbor CRTC1 (show CRTC1 Antibodies)-MAML2 (show MAML2 Antibodies) and CRTC3-MAML2 (show MAML2 Antibodies) fusion transcripts, respectively, or MAML2 (show MAML2 Antibodies) gene rearrangement.
mucoepidermoid carcinoma of the salivary glands positive for CRTC1 (show CRTC1 Antibodies)-MAML2 (show MAML2 Antibodies) or CRTC3-MAML2 (show MAML2 Antibodies) fusion formed a favourable tumour subset that was distinct from fusion-negative cases
As a common human CRTC3 variant with increased transcriptional activity is associated with adiposity in two distinct Mexican-American cohorts, results suggest that adipocyte CRTC3 may play a role in the development of obesity in humans
Mucoepidermoid carcinomas possessing CRTC3-MAML2 (show MAML2 Antibodies) fusion may be associated with favorable clinicopathological features and patients may be younger than those with CRTC1 (show CRTC1 Antibodies)-MAML2 (show MAML2 Antibodies) fusion or those with no detectable gene fusion.
transducer of regulated cyclic AMP-response element-binding protein 3 (show HSPB3 Antibodies) (TORC3), a co-activator of CREB (show CREB1 Antibodies), is involved in Tax (show CNTN2 Antibodies)-induced transcriptional activation from the HTLV-I LTR
These results strongly suggest that TORCs play a key role in linking these external signals to the transcriptional program of adaptive mitochondrial biogenesis by activating PGC-1alpha (show PPARGC1A Antibodies) gene transcription.
BCL3 (show BCL3 Antibodies) functions as a repressor of HTLV-1 LTR-mediated transcription through interactions with TORC3
study reports for the first time a CRTC3-MAML2 (show MAML2 Antibodies) fusion gene in a mucoepidermoid carcinoma, as determined by RT-PCR and sequencing.
This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
transducer of regulated CREB protein 3
, CREB regulated transcription coactivator 3
, CREB-regulated transcription coactivator 3
, transducer of CREB protein 3
, transducer of regulated cAMP response element-binding protein 3
, CREB-regulated transcription coactivator 3-like
, transducer of regulated cAMP response element-binding protein (CREB) 3