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CSE1 Chromosome Segregation 1-Like (Yeast) Proteins (CSE1L)

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Additionally we are shipping CSE1L Antibodies (79) and CSE1L Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse CSE1L CSE1L 110750 Q9ERK4
CSE1L 1434 P55060
Rat CSE1L CSE1L 362273  
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Top CSE1L Proteins at

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days

CSE1L Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

More Proteins for CSE1 Chromosome Segregation 1-Like (Yeast) (CSE1L) Interaction Partners

Fruit Fly (Drosophila melanogaster) CSE1 Chromosome Segregation 1-Like (Yeast) (CSE1L) interaction partners

  1. an important role for Cas proteins in cell-cell adhesion signaling in development

Mouse (Murine) CSE1 Chromosome Segregation 1-Like (Yeast) (CSE1L) interaction partners

  1. serum phospho-CSE1L is useful for early detecting the efficacy of targeted therapy in initial treatment.

  2. CSE1L knockdown reduced Ras-induced metastasis of B16F10 melanoma cells in C57BL/ (show HRAS Proteins)6 mice. v-H-Ras expression altered the cellular trafficking of CSE1L and increased CSE1L secretion.

  3. Serum cellular apoptosis susceptibility protein may have a role in progression of metastatic colorectal cancer

  4. CSE1L/CAS has a role in proliferation and apoptosis [review]

Zebrafish CSE1 Chromosome Segregation 1-Like (Yeast) (CSE1L) interaction partners

  1. Cse1l is a negative regulator of cystic fibrosis transmembrane conductance regulator (show CFTR Proteins)-dependent fluid secretion.

Human CSE1 Chromosome Segregation 1-Like (Yeast) (CSE1L) interaction partners

  1. There is a relationship between nuclear CSE1L overexpression and distant metastasis in breast cancer.

  2. CAS plays contrasting roles in proliferation and apoptosis

  3. hCAS/CSE1L is responsible for controlling the homologous recombinational repair activity by directly interacting with RAD51 (show RAD51 Proteins).

  4. nuclear CSE1L is mainly non-phosphorylated CSE1L and is involved in gene regulation and cytoplasmic CSE1L is mainly phosphorylated CSE1L and is involved in cytoplasmic signaling regulation in melanocytic tumorigenesis.

  5. These results indicate that CSE1L is associated with viability and apoptosis, cellular adhesion and invasion, thus implicating CSE1L in the progression of colorectal cancer.

  6. The cellular apoptosis susceptibility/importin (show KPNA4 Proteins)-alpha1 transport cycle is linked to X-linked inhibitor (XIAP (show XIAP Proteins)) and is required to maintain tumor cell survival in hepatocellular carcinoma.

  7. CSE1L expression was significantly inhibited in RKO cells, causing cell cycle arrest in the G2/M and S phases and a delay in cell proliferation, as well as induction of apoptosis and an inhibition of colony growth capacity.

  8. Most colorectal tumors were positive for CSE1L staining (98.4%). CRT's with K-Ras (show HRAS Proteins) mutation or high cytoplasmic CSE1L expression were correlated with T status (depth of tumor penetration; P = .004), stage (P = .004), and lymph node metastasis (P = .019).

  9. Our results suggest that urinary CSE1L deserves further evaluation for the screening of bladder cancer.

  10. CSE1L- and inhibitor of DNA binding-3 (ID3 (show ID3 Proteins))-overexpression was associated with the diagnosis of BL and signal transduction and transcription-3 (STAT3 (show STAT3 Proteins)) with DLBCL (P<0.001 for all markers). All three markers were associated with patient outcome in DLBCL

CSE1L Protein Profile

Protein Summary

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with CSE1L

  • CAS/CSE1 segregation protein (Cas)
  • CSE1 chromosome segregation 1-like (yeast) (CSE1L)
  • CSE1 chromosome segregation 1-like (yeast) (cse1l)
  • chromosome segregation 1-like (S. cerevisiae) (Cse1l)
  • chromosome segregation 1-like (S. cerevisiae) (cse1l)
  • CSE1 chromosome segregation 1-like (cse1l)
  • CSE1 chromosome segregation 1-like (yeast) (Cse1l)
  • 2610100P18Rik protein
  • AA407533 protein
  • BcDNA:LD14270 protein
  • Capts protein
  • Cas protein
  • CG13281 protein
  • CSE1 protein
  • CSE1L protein
  • dcas protein
  • DKFZp459E1929 protein
  • Dmel\\CG13281 protein
  • Exportin-2 protein
  • l(2)k03902 protein
  • xpo2 protein

Protein level used designations for CSE1L

CG13281-PA , Cas-PA , Importin-alpha re-exporter , CSE1 chromosome segregation 1-like (yeast) , CSE1 chromosome segregation 1-like protein , CSE1 chromosome segregation 1-like , exportin-2-like , chromosome segregation 1-like protein , exp2 , exportin-2 , importin-alpha re-exporter , bao , baobab , cellular apoptosis susceptibilit , cellular apoptosis susceptibility , exportin 2 , cellular apoptosis susceptibility protein

35016 Drosophila melanogaster
458318 Pan troglodytes
704301 Macaca mulatta
100023432 Monodelphis domestica
100056886 Equus caballus
100075465 Ornithorhynchus anatinus
100172855 Pongo abelii
100393152 Callithrix jacchus
100483977 Ailuropoda melanoleuca
100542094 Meleagris gallopavo
100559262 Anolis carolinensis
110750 Mus musculus
30707 Danio rerio
444464 Xenopus laevis
1434 Homo sapiens
419212 Gallus gallus
518622 Bos taurus
362273 Rattus norvegicus
477257 Canis lupus familiaris
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