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anti-CUGBP, Elav-Like Family Member 1 (CELF1) Antibodies

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Additionally we are shipping CELF1 Kits (12) and CELF1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CELF1 10658 Q92879
CELF1 13046 P28659
CELF1 362160 Q4QQT3
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Top anti-CELF1 Antibodies at

Showing 10 out of 81 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB CUGBP1 Antibody (N-term) (ABIN657957) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the CUGBP1 antibody detected the CUGBP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
Cow Mouse Un-conjugated FACS, GS, ICC, IF, IHC, IHC (fro), IHC (p), IP, SimWes, WB Detection of the subcellular distribution of CUGBP1 (nuclear, non-nucleolar) in normal and DM1 (dystrophia myotonica) myoblasts using ABIN152357. Detection of CUG-BP1 in several cell lysates using ABIN152357. 0.1 mL Log in to see 5 to 7 Days
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-CUGBP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa/HepG2 cells, using CELF-1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry (IHC) analyzes of CUG-BP1/2 antibody in paraffin-embedded human brain tissue. Western blot (WB) analysis of CUG-BP1/2 antibody in extracts from HeLa cells. 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
Human Mouse Un-conjugated IF, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-CUGBP1 mouse monoclonal antibody. (ABIN2452904, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-CUGBP1 mouse monoclonal antibody. (ABIN2452904, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
Chicken Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of CUGBP1 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of CUGBP1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
Human Rabbit Un-conjugated IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days

CELF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) , , ,
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Top referenced anti-CELF1 Antibodies

  1. Cow (Bovine) Monoclonal CELF1 Primary Antibody for FACS, GS - ABIN152357 : Kress, Gautier-Courteille, Osborne, Babinet, Paillard: Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice. in Molecular and cellular biology 2007 (PubMed)
    Show all 11 references for ABIN152357

  2. Human Polyclonal CELF1 Primary Antibody for IHC (p), WB - ABIN657957 : Le Tonquèze, Gschloessl, Namanda-Vanderbeken, Legagneux, Paillard, Audic: Chromosome wide analysis of CUGBP1 binding sites identifies the tetraspanin CD9 mRNA as a target for CUGBP1-mediated down-regulation. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 3 references for ABIN657957

More Antibodies against CELF1 Interaction Partners

Human CUGBP, Elav-Like Family Member 1 (CELF1) interaction partners

  1. High expression of CUGBP1 is associated with recurrence in lung adenocarcinoma.

  2. CUG-BP1 affected the calcium release activity in single myofibers and the extent of atrophy was significantly reduced upon gene silencing of CUG-BP1 in atrophic muscle.

  3. these data provided a comprehensive view of the CELF1 mRNA regulatory network in oral cancer

  4. forced expression of miR (show MLXIP Antibodies)-214-3p enhances the sensitivity of esophageal cancer cells to cisplatin-induced apoptosis. This effect is abrogated with rescue expression of survivin (show BIRC5 Antibodies) or CUG-BP1

  5. Expression of several genes within the CELF1 locus, including MTCH2 (show MTCH2 Antibodies), were highly correlated with one another and were associated with Alzheimer's disease status.

  6. CUGBP1 and HuR (show ELAVL1 Antibodies) negate each other's effects in regulating E-cadherin (show CDH1 Antibodies) translation by altering the recruitment of E-cadherin (show CDH1 Antibodies) mRNA to PBs (show TSPO Antibodies) and play important roles in the regulation of intestinal barrier integrity.

  7. CUGBP1 promotes cell proliferation and suppresses apoptosis via down-regulating C-EBPalpha (show CEBPA Antibodies) in human non-small cell lung cancers.

  8. The results indicate that the cellular level of miR (show MLXIP Antibodies)-122 is determined by the balance between the opposing effects of GLD-2 (show PAPD4 Antibodies) and PARN (show PARN Antibodies)/CUGBP1 on the metabolism of its 3'-terminus.

  9. CELF1 dysfunction in malignant T cells led to the up-regulation of a subset of GRE-containing transcripts that promote cell growth and down-regulation of another subset that suppress cell growth

  10. Celf1 has a role in vegetal RNA localization during Xenopus oogenesis

Mouse (Murine) CUGBP, Elav-Like Family Member 1 (CELF1) interaction partners

  1. CELF1 downregulates Cyp19a1 (Aromatase (show CYP19A1 Antibodies)) posttranscriptionally to achieve high concentrations of testosterone compatible with spermiogenesis completion.

  2. developmental stage-specific compatibility of CELF (show CEBPD Antibodies)-dependent splice variants dictates their effects on cardiac health and function

  3. Differential expression of CELF1 in development plays a role in alternative splicing of vesicular trafficking genes in postnatal heart development.

  4. Celf1 plays a distinctive and negative role in terminal myocyte differentiation, which partially contribute to DM1 RNA toxicity.

  5. These results indicate that JNK2 (show MAPK9 Antibodies) is essential for maintenance of normal intestinal epithelial homeostasis and maturation under biological conditions by differentially modulating HuR (show ELAVL1 Antibodies) and CUGBP1.

  6. CELF1 and CELF2 (show CELF2 Antibodies) may underlie conserved, developmentally regulated, tissue-specific processes in vertebrate embryos

  7. Mitochondrial biogenesis occurs in the presence of increased CUG-BP1 and AUF1 (show HNRNPD Antibodies), suggesting that reductions in known mRNA destabilizing proteins likely does not contribute to exercise-induced mitochondrial biogenesis.

  8. these results strongly support a role for -mediated alternative splicing in the regulation of contractile gene expression, achieved in part through modulating the activity of SRF, a key cardiac transcription factor.

  9. This review is focused on the role of a conserved, multifunctional RNA-binding protein, CUGBP1, in the development of aging phenotype in the liver.

  10. disruption of Celf1 gene is also responsible for a fully penetrant delayed first wave of spermatogenesis, and a delay of steroidogenesis may be the cause for the delay of germ cells differentiation

Zebrafish CUGBP, Elav-Like Family Member 1 (CELF1) interaction partners

  1. Results therefore suggest that Celf1 regulates proper organogenesis of endoderm-derived tissues by regulating the expression of such targets.

  2. Celf1-dependent fine-tuning of dmrt2a (show DMRT2 Antibodies) expression is essential for generating bilateral symmetry of somites and left-right asymmetric patterning during zebrafish development.

  3. not only mRNA but also protein of brul is localized to the zebrafish germ plasm at the ends of the cleavage furrows

Xenopus laevis CUGBP, Elav-Like Family Member 1 (CELF1) interaction partners

  1. This "target protector and rescue assay" demonstrates that the phenotypic defects associated with CUGBP1 inactivation in Xenopus are essentially due to the deregulation of Su(H (show RBPJ Antibodies)) mRNA.

CELF1 Antigen Profile

Protein Summary

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with CELF1

  • CUGBP, Elav-like family member 1 (CELF1) antibody
  • CUGBP, Elav-like family member 1 (Celf1) antibody
  • cugbp, Elav-like family member 1 (celf1) antibody
  • CUGBP, Elav-like family member 1 (celf1-a) antibody
  • 1600010O03Rik antibody
  • AA407467 antibody
  • brul antibody
  • Bruno-like antibody
  • brunol2 antibody
  • cb920 antibody
  • cug-bp antibody
  • cug-bp1 antibody
  • cugbp antibody
  • cugbp1 antibody
  • cugbp1-a antibody
  • D2Wsu101e antibody
  • eden-bp antibody
  • edenbp antibody
  • HNAB50 antibody
  • nab50 antibody
  • NAPOR antibody

Protein level used designations for CELF1

CUG triplet repeat, RNA binding protein 1 , CUGBP Elav-like family member 1 , 50 kDa nuclear polyadenylated RNA-binding protein , CELF-1 , CUG RNA-binding protein , CUG triplet repeat RNA-binding protein 1 , CUG triplet repeat, RNA-binding protein 1 , CUG-BP- and ETR-3-like factor 1 , CUG-BP1 , EDEN-BP homolog , RNA-binding protein BRUNOL-2 , bruno-like 2 , bruno-like protein 2 , deadenylation factor CUG-BP , embryo deadenylation element binding protein , embryo deadenylation element-binding protein homolog , nuclear polyadenylated RNA-binding protein, 50-kD , brain protein F41 , deadenylation factor EDEN-BP , EDEN-BP/Bruno-like protein , CELF-1A , CUG triplet repeat RNA-binding protein 1-A , CUG-BP- and ETR-3-like factor 1-A , CUG-BP1-A , CUGBP Elav-like family member 1-A , EDEN-BP-A , RNA-binding protein BRUNOL-2-A , bruno-like protein 2-A , embryo deadenylation element-binding protein A , p53/p55

540475 Bos taurus
10658 Homo sapiens
13046 Mus musculus
362160 Rattus norvegicus
58137 Danio rerio
373923 Gallus gallus
399360 Xenopus laevis
100514512 Sus scrofa
100354668 Oryctolagus cuniculus
100730258 Cavia porcellus
101118301 Ovis aries
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