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CUGBP, Elav-Like Family Member 2 Proteins (CELF2)

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Additionally we are shipping CELF2 Antibodies (53) and CELF2 Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CELF2 10659 O95319
CELF2 14007 Q9Z0H4
CELF2 29428 Q792H5
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Top CELF2 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,367.83
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,443.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CELF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for CUGBP, Elav-Like Family Member 2 (CELF2) Interaction Partners

Human CUGBP, Elav-Like Family Member 2 (CELF2) interaction partners

  1. the genetic variant rs3740194 in CELF2 gene might be a valuable predictor for NPC (show NPC1 Proteins) prognosis

  2. Data show miR95 expression level positively related to glioma grade and its downregulation affects proliferation, invasion and apoptosis by targeting CELF2. MiR95 is identified as a putative therapeutic target and CELF2 as a potential tumor suppressor.

  3. a widespread role for the JNK (show MAPK8 Proteins)-CELF2 axis in controlling splicing during T-cell activation, including a specific role in propagating JNK (show MAPK8 Proteins) signaling.

  4. The A allele of rs2242451 in CUGBP2 might decrease Alzheimer disease risk in the Chinese Han population.

  5. novel mechanisms for CELF2 regulation that may broadly impact CELF2 expression across diverse cell types.

  6. There was evidence of association for recently-reported late-onset Alzheimer's disease risk loci, including BIN1 (show BIN1 Proteins) and CLU (show CLU Proteins) and CUGBP2 with APOE (show APOE Proteins).

  7. Alternative splicing of LEF1 (show LEF1 Proteins) exon 6 is regulated during pre-TCR signaling in thymic development and in response to activation of the JSL1 T-cell line and this is driven by the activity of CELF2.

  8. results indicate the occurrence of a mis (show AMH Proteins)-splicing event in myotonic dystrophy type 1 that is induced neither by a loss of muscleblind-like 1 (MBNL1 (show MBNL1 Proteins)) function nor by a gain of CUGBP1 (show CELF1 Proteins)

  9. BRUNOL3 appears to be an important factor for thymus development and is therefore a candidate gene for the thymus hypoplasia/aplasia seen in partial monosomy 10p patients.

  10. Determination of ETR-3 protein domains required for RNA splicing.

Mouse (Murine) CUGBP, Elav-Like Family Member 2 (CELF2) interaction partners

  1. CELF1 (show CELF1 Proteins) and CELF2 may underlie conserved, developmentally regulated, tissue-specific processes in vertebrate embryos

  2. Napor-3 suppression by ethanol during mid and late stage fetal brain converts natural physiological event apoptosis into a pathological process.

  3. Colonic MSCs expressed high Ptgs2 levels as a consequence of mRNA stabilization downstream of Fgf9. This stabilization was mediated partially through a mechanism involving endogenous CUG-binding protein 2.

  4. A renmarkable decrease in CUG-binding protein-2 (Cugbp2) expression is seen in the pyramidal cells of the hippocampus following neuronal degeneration.

  5. NAPOR may be one of a group of closely related proteins involved in splicing regulation within the brain.

  6. Data demonstrate that cells expressing CUGBP2 variant 1 undergo apoptosis during mitosis, suggesting mitotic catastrophe.

  7. CUGBP2 interacts with functionally significant RNA motifs surrounding the branch sites upstream of exon 6 of the CUGBP2 transcript itself.

Zebrafish CUGBP, Elav-Like Family Member 2 (CELF2) interaction partners

  1. Cloning and expression of Napor/CUG-BP2 in embryo development.

CELF2 Protein Profile

Protein Summary

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with CELF2

  • CUG triplet repeat, RNA binding protein 2 (CUGBP2)
  • CUGBP, Elav-like family member 2 (CELF2)
  • CUGBP, Elav-like family member 2 (Celf2)
  • cugbp, Elav-like family member 2 (celf2)
  • CUGBP, Elav-like family member 2 (celf2-a)
  • B230218O03 protein
  • B230345P09Rik protein
  • Brunol3 protein
  • C88023 protein
  • cb906 protein
  • CELF-2 protein
  • celf2 protein
  • CUG-BP2 protein
  • cugbp2 protein
  • cugbp2-a protein
  • D230046B21Rik protein
  • Etr-3 protein
  • Etr3 protein
  • fj87b07 protein
  • mETR-3 protein
  • napor protein
  • Napor-2 protein
  • wu:fj87b07 protein

Protein level used designations for CELF2

CUG triplet repeat, RNA binding protein 2 , CELF-2 , CUG triplet repeat RNA-binding protein 2 , CUG-BP- and ETR-3-like factor 2 , CUG-BP2 , CUGBP Elav-like family member 2 , ELAV-type RNA-binding protein 3 , RNA-binding protein BRUNOL-3 , bruno-like protein 3 , hNAPOR , neuroblastoma apoptosis-related RNA-binding protein , elav-type RNA-binding protein 3 , mNapor , napor , CUG triplet repeat, RNA binding protein 2-a , ETR-3 , Cugbp- and Etr3-like factor 2 , RNA-binding protein Brunol3 , CUG triplet repeat RNA binding protein 2

GENE ID SPECIES
450298 Pan troglodytes
100056973 Equus caballus
10659 Homo sapiens
14007 Mus musculus
373117 Danio rerio
379280 Xenopus laevis
374111 Gallus gallus
607310 Canis lupus familiaris
29428 Rattus norvegicus
100724393 Cavia porcellus
448999 Sus scrofa
101107886 Ovis aries
777790 Bos taurus
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